Proposed Maximum Residue Limit PMRL2019-23, Cyclaniliprole
Notice to the reader:
This consultation is now closed.
Pest Management Regulatory Agency
29 August 2019
ISSN: 1925-0843 (PDF version)
Catalogue number: H113-24/2019-23E-PDF (PDF Format)
Under the authority of the Pest Control Products Act, Health Canada's Pest Management Regulatory Agency (PMRA) has concluded that the addition of new uses on various commodities and amendments to the currently registered uses on the product labels of Cyclaniliprole 50 SL Insecticide and Harvanta 50 SL Insecticide, containing technical grade cyclaniliprole, are acceptable. The specific uses approved in Canada are detailed on the labels of Cyclaniliprole 50 SL Insecticide and Harvanta 50 SL Insecticide, Pest Control Products Act Registration Numbers 32862 and 32889, respectively.
The evaluation of these cyclaniliprole applications indicated that the end-use products have value and the human health and environmental risks associated with the new uses are acceptable.
Before registering a pesticide for food use in Canada, the PMRA must determine the quantity of residues that are likely to remain in or on the food when the pesticide is used according to label directions and that such residues will not be a concern to human health. This quantity is then legally established as a maximum residue limit (MRL). An MRL applies to the identified raw agricultural food commodity as well as to any processed food product that contains it, except where separate MRLs are specified for the raw agricultural commodity and a processed product made from it.
Consultation on the proposed MRLs for cyclaniliprole is being conducted via this document (see Next Steps). A summary of the field trial data used to support the proposed MRLs can be found in Appendix I.
To comply with Canada's international trade obligations, consultation on the proposed MRLs is also being conducted internationally by notifying the World Trade Organization, as coordinated by the Canada's Notification Authority and Enquiry Point.
The proposed MRLs, to replace or be added to the MRLs already established for cyclaniliprole, are as follows.
|Common Name||Residue Definition||MRL (ppm)Table 1 footnote 1||Food Commodity|
|Cyclaniliprole||3-bromo-N-[2-bromo-4- chloro-6- [[(1- cyclopropylethyl)amino]carbo nyl] phenyl]-1-(3-chloro-2- pyridinyl)-1H pyrazole-5-carboxamide||10||Leafy vegetables (crop group 4-13)Table 1 footnote 2|
|1.5||Bushberries (crop subgroup 13-07B)|
|1.0||Small fruits vine climbing, except grapes (crop subgroup 13-07E)Table 1 footnote 3|
|0.8||Caneberries (crop subgroup 13-07A), Brassica head and stem vegetable group (crop group 5-13)Table 1 footnote 4|
|0.7||Stone fruits (crop group 12-09)Table 1 footnote 5|
|0.6||GrapesTable 1 footnote 6|
|0.4||Low growing berries, except lowbush blueberries, (crop subgroup 13-07G)|
|0.1||Cucurbit vegetables (crop group 9)Table 1 footnote 7|
|0.02||Tree nuts (crop group 14-11)Table 1 footnote 8|
|0.01||Tuberous and corm vegetables (crop subgroup 1C)|
MRLs are proposed for each commodity included in the listed crop groupings in accordance with the Residue Chemistry Crop Groups webpage in the Pesticides section of the Canada.ca website.
MRLs established in Canada may be found using the Maximum Residue Limit Database on the Maximum Residue Limits for Pesticides webpage. The database allows users to search for established MRLs, regulated under the Pest Control Products Act, both for pesticides or for food commodities.
International Situation and Trade Implications
Cyclaniliprole is an active ingredient that is concurrently being registered in Canada and the United States for use on tuberous and corm vegetables (crop subgroup 1C), caneberries (crop subgroup 13-07A), bushberries, (crop subgroup 13-07B), small fruits vine climbing, except grapes (crop subgroup 13-07E) and low growing berries (crop subgroup 13-07G). The amendments to the use instructions on leafy vegetables (CG 4-13), Brassica head and stem vegetables (CG 5-13), fruiting vegetables (CG 8-09), cucurbit vegetables (CG 9), pome fruit (CG 11-09), stone fruit (CG 12-09), grapes and tree nuts (CG 14-11) are also concurrently being approved in Canada and the United States. The MRLs proposed for cyclaniliprole in Canada are the same as corresponding tolerances to be promulgated in the United States.
Once established, the American tolerances for cyclaniliprole will be listed inthe Electronic Code of Federal Regulations, 40 CFR Part 180, by pesticide.
The PMRA invites the public to submit written comments on the proposed MRLs for cyclaniliprole up to 75 days from the date of publication of this document. Please forward your comments to Publications. The PMRA will consider all comments received before making a final decision on the proposed MRLs. Comments received will be addressed in a separate document linked to this PMRL. The established MRLs will be legally in effect as of the date that they are entered into the Maximum Residue Limit Database.
Summary of Field Trial Data Used to Support the Proposed Maximum Residue Limits
Residue data for cyclaniliprole in potatoes, raspberries, blueberries, fuzzy kiwifruits and strawberries were submitted to support the domestic use of Cyclaniliprole 50 SL Insecticide and Harvanta 50 SL Insecticide on tuberous and corm vegetables (crop subgroup 1C), caneberries (crop subgroup 13-07A), bushberries, (crop subgroup 13-07B), small fruits vine climbing, except grapes (crop subgroup 13-07E) and low growing berries (crop subgroup 13-07G). A processing study in treated potatoes was also reviewed to determine the potential for concentration of residues of cyclaniliprole into processed commodities. In addition, previously reviewed residue data from field trials conducted in/on leafy vegetables (CG 4-13), Brassica head and stem vegetables (CG 5-13), fruiting vegetables (CG 8-09), cucurbit vegetables (CG 9), pome fruit (CG 11-09), stone fruit (CG 12-09), grapes and tree nuts (CG 14-11) were reassessed based on the amendments to the use instructions.
Maximum Residue Limits
The recommendation for maximum residue limits (MRLs) for cyclaniliprole was based upon the submitted field trial data, and the guidance provided in the OECD MRL Calculator. Table A1 summarizes the residue data used to calculate the proposed MRLs for tuberous and corm vegetables (crop subgroup 1C), caneberries (crop subgroup 13-07A), bushberries, (crop subgroup 13-07B), small fruits vine climbing, except grapes (crop subgroup 13-07E) and low growing berries, except lowbush blueberries, (crop subgroup 13-07G); and to revise the existing MRLs for leafy vegetables (crop group 4-13), Brassica head and stem vegetable group (crop group 5-13), cucurbit vegetables (crop group 9), stone fruits (crop group 12-09), grapes and tree nuts (crop group 14-11).
|Commodity||Application Method/ Total Application Rate
(g ai/ha)Table A1 footnote 1
|Preharvest Interval (days)||Lowest Average Field Trial Residues
|Highest Average Field Trial Residues
|Experimental Processing Factor|
|Potato tubers||Foliar broadcast spray / 180||6-7||<0.01||<0.01||No concentration in processed fractions|
|Head lettuce with
|Foliar broadcast spray / 180||1||0.051||2.102||Not required|
|Leaf lettuce leaves||0.181||2.254|
|Mustard green leaves||1.387||4.425|
|Cabbage head||Foliar broadcast spray / 180||1||0.010||0.386||Not required|
|Broccoli head and stem||0.081||0.475|
|Cantaloupe fruit||Foliar broadcast spray / 180||1||0.010||0.064||Not required|
|Summer squash fruit||0.010||0.034|
|Peach fruit||Foliar broadcast spray / 240||7||0.017||0.153||Not applicableTable A1 footnote 2|
|Sweet cherry fruit||0.076||0.256|
|Tart cherry fruit||0.066||0.448|
|Cherries (sweet and tart combined)||0.066||0.448|
|Raspberries||Foliar broadcast spray / 240||1||0.113||0.424||Not required|
|Highbush blueberries||Foliar broadcast spray / 240||1||0.079||0.810||Not required|
|Fuzzy kiwifruits||Foliar broadcast spray / 240||1||0.010||0.394||Not required|
|Strawberries||Foliar broadcast spray / 240||1||0.043||0.275||Not required|
|Grapes||Foliar broadcast spray / 240||7||0.019||0.408||Not applicableTable A1 footnote 2|
|Almond nuts||Foliar broadcast spray / 240||30||0.010||0.011||Not required|
Following the review of all available data, MRLs as proposed in Table 1 are recommended to cover residues of cyclaniliprole. Residues of cyclaniliprole in these crop commodities at the proposed MRLs will not pose an unacceptable risk to any segment of the population, including infants, children, adults and seniors.
- Footnote 1
The Codex Alimentarius Commission is an international organization under the auspices of the United Nations that develops international food standards, including MRLs.
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