Proposed Maximum Residue Limit PMRL2019-36, Fludioxonil
Pest Management Regulatory Agency
27 November 2019
ISSN: 1925-0843 (PDF version)
Catalogue number: H113-24/2019-38E-PDF (PDF version)
Under the authority of the Pest Control Products Act, Health Canada’s Pest Management Regulatory Agency (PMRA) has concluded that the addition of a new use on potatoes to the product label of Pyroxasulfone 85 WG, containing technical grade pyroxasulfone, is acceptable. The specific uses approved in Canada are detailed on the label of Pyroxasulfone 85 WG, Pest Control Products Act Registration Number 30572.
The evaluation of this pyroxasulfone application indicated that the end-use product has value and the human health and environmental risks associated with the new uses are acceptable.
Before registering a pesticide for food use in Canada, the PMRA must determine the quantity of residues that are likely to remain in or on the food when the pesticide is used according to label directions and that such residues will not be a concern to human health. This quantity is then legally established as a maximum residue limit (MRL). An MRL applies to the identified raw agricultural food commodity as well as to any processed food product that contains it, except where separate MRLs are specified for the raw agricultural commodity and a processed product made from it.
Consultation on the proposed MRLs for pyroxasulfone is being conducted via this document (see Next Steps). A summary of the field trial data used to support the proposed MRLs can be found in Appendix I.
To comply with Canada’s international trade obligations, consultation on the proposed MRLs is also being conducted internationally by notifying the World Trade Organization, as coordinated by the Canada’s Notification Authority and Enquiry Point.
The proposed MRLs, to be added to the MRLs already established for pyroxasulfone, are as follows.
|Common Name||Residue Definition||MRL (ppm)Table 1 Footnote 1||Food Commodity|
|Pyroxasulfone||3-[-5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-yl-methylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-oxazole including the metabolites (5-difluoromethoxy-1-methyl-3-trifluoromethyl-1H-pyrazol-4-yl)-methanesulfonic acid, 5-difluoromethoxyl-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid, (5-difluoromethoxy-3-trifluoromethyl-1H-pyrazol-4-yl)-methanesulfonic acid, and 3-[1-carboxy-2-(5,5-dimethyl-4,5-dihydroisoxazol-3-ylthio)ethylamino]-3-oxopropanoic acid (expressed as parent equivalents)||0.2||Potato flakes, potato granules|
MRLs established in Canada may be found using the Maximum Residue Limit Database on the Maximum Residue Limits for Pesticides webpage. The database allows users to search for established MRLs, regulated under the Pest Control Products Act, both for pesticides or for food commodities.
International Situation and Trade Implications
The MRLs proposed for pyroxasulfone in Canada are the same as corresponding American tolerances as listed in the Electronic Code of Federal Regulations, 40 CFR Part 180, by pesticide. Currently, there are no Codex MRLsFootnote 1 listed for pyroxasulfone in or on any commodity on the Codex Alimentarius Pesticide Index webpage.
The PMRA invites the public to submit written comments on the proposed MRLs for pyroxasulfone up to 75 days from the date of publication of this document. Please forward your comments to Publications. The PMRA will consider all comments received before making a final decision on the proposed MRLs. Comments received will be addressed in a separate document linked to this PMRL. The established MRLs will be legally in effect as of the date that they are entered into the Maximum Residue Limit Database.
Summary of Field Trial Data Used to Support the Proposed Maximum Residue Limits
Residue data for pyroxasulfone in potatoes were submitted to support the domestic use of Pyroxasulfone 85 WG on potatoes. In addition, a processing study in treated potatoes was reviewed to determine the potential for concentration of residues of pyroxasulfone into processed commodities.
Maximum Residue Limits
The recommendation for maximum residue limits (MRLs) for pyroxasulfone was based upon the submitted field trial data, and the guidance provided in the OECD MRL Calculator. Table A1 summarizes the residue data used to calculate the proposed MRLs.
(g a.e./ha)Footnote 1
|Experimental Processing Factor|
|Potatoes||Pre-emergence / 250||63-117||0.05||0.05||Chips: 1.0×
Following the review of all available data, MRLs as proposed in Table 1 are recommended to cover residues of pyroxasulfone. Residues of pyroxasulfone in these crop commodities at the proposed MRLs will not pose an unacceptable risk to any segment of the population, including infants, children, adults and seniors.
- Footnote 1
The Codex Alimentarius Commission is an international organization under the auspices of the United Nations that develops international food standards, including MRLs.
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