Proposed Maximum Residue Limit PMRL2020-02, Pyriofenone
Pest Management Regulatory Agency
4 February 2020
ISSN: 1925-0843 (PDF version)
Catalogue number: H113-24/2020-2E-PDF (PDF version)
Under the authority of the Pest Control Products Act, Health Canada's Pest Management Regulatory Agency (PMRA) has concluded that the addition of tomatoes to the product label of Pyriofenone 300SC Fungicide, containing technical grade pyriofenone, is acceptable. The specific uses approved in Canada are detailed on the label of Pyriofenone 300SC Fungicide, Pest Control Products Act Registration Number 32376.
The evaluation of this pyriofenone application indicated that the end-use product has value and the human health and environmental risks associated with the new uses are acceptable.
Before registering a pesticide for food use in Canada, the PMRA must determine the quantity of residues that are likely to remain in or on the food when the pesticide is used according to label directions and that such residues will not be a concern to human health. This quantity is then legally established as a maximum residue limit (MRL). An MRL applies to the identified raw agricultural food commodity as well as to any processed food product that contains it, except where separate MRLs are specified for the raw agricultural commodity and a processed product made from it.
To comply with Canada's international trade obligations, consultation on the proposed MRLs is also being conducted internationally by notifying the World Trade Organization, as coordinated by Canada's Notification Authority and Enquiry Point.
The proposed MRLs for tetraniliprole are as follows.
|Common Name||Residue Definition||MRL (ppm)Footnote 1||Food Commodity|
|Pyriofenone||(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)methanone||0.3||Fruiting vegetables(crop group 8-09)|
MRLs are proposed for each commodity included in the listed crop groupings in accordance with the Residue Chemistry Crop Groups webpage in the Pesticides section of the Canada.ca website.
MRLs established in Canada may be found using the Maximum Residue Limit Database on the Maximum Residue Limits for Pesticides webpage. The database allows users to search for established MRLs, regulated under the Pest Control Products Act, both for pesticides or for food commodities.
International Situation and Trade Implications
The MRL proposed for pyriofenone in Canada is the same as the corresponding American tolerance as listed in the Electronic Code of Federal Regulations, 40 CFR Part 180, by pesticide.
|Food Commodity||Canadian MRL (ppm)||American Tolerance (ppm)||Codex MRL (ppm)|
|Fruiting vegetables (crop group 8-09)||0.3||0.3 (Vegetable, fruiting, crop group 8-10)||Not established|
The PMRA invites the public to submit written comments on the proposed MRL for pyriofenone up to 75 days from the date of publication of this document. Please forward your comments to Publications. The PMRA will consider all comments received before making a final decision on the proposed MRL. Comments received will be addressed in a separate document linked to this PMRL. The established MRL will be legally in effect as of the date that they are entered into the Maximum Residue Limit Database.
Summary of Field Trial Data Used to Support the Proposed Maximum Residue Limit
Residue data for pyriofenone in tomatoes, and bell and non-bell peppers were submitted to support the domestic use of Pyriofenone 300SC Fungicide on crop group 8-09 (fruiting vegetables). In addition, a processing study in treated tomatoes was reviewed to determine the potential for concentration of residues of pyriofenone into processed commodities.
Maximum Residue Limit
The recommendation for maximum residue limit (MRL) for pyriofenone was based upon the submitted field trial data, and the guidance provided in the OECD MRL Calculator. Table A1 summarizes the residue data used to calculate the proposed MRL for crop group 8-09 (fruiting vegetables).
Total Application Rate
Field Trial Residues
Field Trial Residues
|Experimental Processing Factor|
|Bell Peppers||Foliar Broadcast/
|Non-bell Peppers||Foliar Broadcast/
Following the review of all available data, the MRL as proposed in Table 1 is recommended to cover residues of pyriofenone. Residues of pyriofenone in these crop commodities at the proposed MRL will not pose an unacceptable risk to any segment of the population, including infants, children, adults and seniors.
- Footnote 1
The Codex Alimentarius Commission is an international organization under the auspices of the United Nations that develops international food standards, including MRLs.
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