Consultation on Piperonyl Butoxide and Its Associated End-use Products, Proposed Re‑evaluation Decision PRVD2020-09

Notice to the reader:

The online consultation is now closed.

As of 18 December 2020, the consultation period has been extended. Interested parties are encouraged to provide comments and suggestions by 1 March 2021.

Health Canada is consulting Canadians on the proposal to continue registration of piperonyl butoxide in Canada provided that the proposed risk mitigation measures in PRVD2020-09 are in place to protect human health and the environment. The proposed decision includes the cancellation of several uses, where the value or risks associated with consumers, bystanders or workers have not been shown to be acceptable.

Piperonyl butoxide is a synergist that is always co-formulated with an insecticide to enhance the effectiveness of the co-formulated active ingredients. Products containing piperonyl butoxide are used to control a broad spectrum of insect pests on a wide variety of sites, including commercial and domestic agricultural and structural uses. Piperonyl butoxide is a component of the integrated pest management of common household pests, such as bed bugs, cockroaches, fleas, and indoor ants.

The use patterns identified in the summary tables outlined in Appendix I of PRVD 2020-09 were used as the basis of the risk assessment.
A complete list of currently registered products containing piperonyl butoxide can be found in the Pesticide Label Search results.

For more information on the proposed decision, including details on label statements and all mitigation measures proposed as a result of the re-evaluation, visit the “Proposed Re-evaluation Decision”.

How to Get Involved

This consultation is open for comment from 17 September 2020 to 16 December 2020 (90 calendar days).

To comment on PRVD2020-09:

Step 1
Request the full consultation document to read the Science Evaluation that is the basis of this proposed regulatory decision.
Step 2
Submit comments to the PMRA Publications Section.

All comments received will be considered. A final re-evaluation decision will consider additional scientific information provided during the public comment period.

Please refer to the document title (for example: PRVD2020-09, Piperonyl Butoxide and Its Associated End-use Products) when providing comments.

Reporting to Canadians

Health Canada will make the results of this consultation available on this website. Once the decision is finalized, the PMRA will post a Re-evaluation Decision on the Pesticides and Pest Management Reports and Publications portion of

If you have any questions, contact the Pest Management Information Service.

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