Exceptional importation and sale of drugs in relation to COVID-19: Tier 3 drug shortages

Tier 3 shortages are those that have the greatest potential impact on Canada's drug supply and health care system. Impact is based on low availability of alternative supplies, ingredients or therapies.

The Tier Assignment Committee (TAC), which includes federal and provincial/territorial governments, healthcare professionals, and industry stakeholders, makes recommendations on the tier assignment of drug shortages. The TAC assessment includes:

Drug (Active Ingredient) Date of Tier 3 Determination TAC Committee Membership Used in the treatment of COVID-19 and/or related conditions (Yes/No)
Acenocoumarol - Sintrom December 18, 2020

Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, University Health Network

No
Asfotase Alfa - Strensiq Proactively assigned October 27, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Paediatric Society No
Asparaginase - Erwinase July 16, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Provincial Cancer Agencies No
Medroxyprogesterone Acetate - Injectable suspension Proactively assigned March 18, 2021 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Society of Obstetricians and Gynaecologists of Canada No
Phenelzine June 2, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Psychiatric Association No
Propofol Proactively assigned March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Propylthiouracil May 25, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Endocrinology and Metabolism, Canadian Society of Hospital Pharmacists No
Rocuronium Proactively assigned March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Single Ingredient Timolol Maleate - Ophthalmic Indications April 17, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Optometrists Association, Canadian Ophthalmology Society No
Tocilizumab for Injection (IV) February 19, 2021 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Rheumatology Association Yes
Verteporfin Proactively assigned September 10, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Ophthalmology Society No
Cisatracurium Proactively assigned January 28, 2021 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Trifluoperazine (trifluoperazine hydrochloride) February 26, 2021 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Psychiatric Association No
Hydromorphone- Oral Syrup March 5, 2021 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society, Canadian Society of Palliative Care Physicians Yes
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