Exceptional importation and sale of drugs in relation to COVID-19: Tier 3 drug shortages

Tier 3 shortages are those that have the greatest potential impact on Canada's drug supply and health care system. Impact is based on low availability of alternative supplies, ingredients or therapies.

The Tier Assignment Committee (TAC), which includes federal and provincial/territorial governments, healthcare professionals, and industry stakeholders, makes recommendations on the tier assignment of drug shortages. The TAC assessment includes:

Drug (Active Ingredient) Date of Tier 3 Determination TAC Committee Membership Used in the treatment of COVID-19 and/or related conditions (Yes/No)
Alemtuzumab May 19, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Association of Provincial Cancer Agencies, Alberta Health Services No
Methotrimeprazine Proactively assigned April 28, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Society of Palliative Care Physicians Yes
Phenobarbital — Injectable formats Proactively assigned May 1, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Society of Palliative Care Physicians Yes
Atracurium Proactively assigned April 13, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Azithromycin — Injectable formats April 14, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Association of Medical Microbiology and Infectious Disease Canada Yes
Ceftriaxone — Injectable formats Proactively assigned on April 24, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Association of Medical Microbiology and Infectious Disease Canada Yes
Cisatracurium Proactively assigned on March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Dexamethasone — Oral formats May 1, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Association of Medical Oncologists, Canadian Association of Provincial Cancer Agencies No
Dexmedetomidine Proactively assigned on March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Epinephrine Proactively assigned on April 16, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Emergency Physicians Yes
Ethambutol April 27, 2020 Health Canada, Public Health Agency of Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association No
Fentanyl — Injectable formats Proactively assigned April 9, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Hydromorphone — Injectable formats Proactively assigned April 9, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Hydroxyurea May 1, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Association of Medical Oncologists, Canadian Association of Provincial Cancer Agencies No
Ketamine Proactively assigned on March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Lorazepam Proactively assigned on March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Meropenem — Injectable formats Proactively assigned April 24, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Association of Medical Microbiology and Infectious Disease Canada Yes
Midazolam Proactively assigned on March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Morphine — Injectable formats Proactively assigned April 9, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Norepinephrine Proactively assigned April 16, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Emergency Physicians Yes
Pancuronium Proactively assigned April 13, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Propofol Proactively assigned on March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Propylthiouracil May 25, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Endocrinology and Metabolism, Canadian Society of Hospital Pharmacists No
Rocuronium Proactively assigned on March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Salbutamol — Metered dose inhaler March 26, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Thoracic Society Yes
Succinylcholine chloride Proactively assigned on March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Tocilizumab Proactively assigned April 30, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Rheumatology Association, Canadian Pharmacists Association Yes
Single Ingredient Timolol Maleate — Ophthalmic Indications April 17, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Optometrists Association, Canadian Ophthalmology Society No
Vecuronium Proactively assigned April 13, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
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