Exceptional importation and sale of drugs in relation to COVID-19: Tier 3 drug shortages

Tier 3 shortages are those that have the greatest potential impact on Canada's drug supply and health care system. Impact is based on low availability of alternative supplies, ingredients or therapies.

The Tier Assignment Committee (TAC), which includes federal and provincial/territorial governments, healthcare professionals, and industry stakeholders, makes recommendations on the tier assignment of drug shortages. The TAC assessment includes:

Drug (Active Ingredient) Date of Tier 3 Determination TAC Committee Membership Used in the treatment of COVID-19 and/or related conditions (Yes/No)
Acyclovir - Injectable formats June 23, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Association of Medical Microbiology and Infectious Disease Canada, Canadian Society of Hospital Pharmacists No
Asparaginase - Erwinase July 16, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Provincial Cancer Agencies No
Dexamethasone - Oral formats May 1, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Association of Medical Oncologists, Canadian Association of Provincial Cancer Agencies Yes
Dexmedetomidine Proactively assigned March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Dexrazoxane September 24, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Pediatric Oncology Group of Ontario and Canadian Association of Provincial Cancer Agencies. No
Heparin Sodium - Heparin Sodium in 5% Dextrose Injection October 1, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists No
Hydroxyurea May 1, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Association of Medical Oncologists, Canadian Association of Provincial Cancer Agencies No
Isoproterenol Hydrochloride Proactively assigned October 2, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Cardiovascular Society No
Ketamine Proactively assigned March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Lorazepam Proactively assigned March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Methotrimeprazine - Injectable formats Proactively assigned April 28, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Society of Palliative Care Physicians Yes
Midazolam Proactively assigned March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Penicillin G - Injectable formats June 23, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Association of Medical Microbiology and Infectious Disease Canada, Canadian Society of Hospital Pharmacists No
Phenelzine June 2, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Psychiatric Association No
Propofol Proactively assigned March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Propylthiouracil May 25, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Endocrinology and Metabolism, Canadian Society of Hospital Pharmacists No
Rocuronium Proactively assigned March 31, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Critical Care Society Yes
Salbutamol - Metered dose inhaler March 26, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Thoracic Society Yes
Single Ingredient Timolol Maleate - Ophthalmic Indications April 17, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Optometrists Association, Canadian Ophthalmology Society No
Buprenorphine Extended Release Injection Sublocade September 11, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Society of Addiction Medicines No
Verteporfin Proactively assigned September 10, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Ophthalmology Society No
Remdesivir August 4, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Association of Medical Microbiology and Infectious Disease Canada Yes
Vasopressin September 30, 2020 Health Canada, Ontario Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Emergency Physicians Yes
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