ARCHIVED: Appendix 4: The Management of the National Antiviral Stockpile: Options Report - Comparison of international stockpiling tends

 

Appendix 4: Comparison of International Stockpiling Trends
Country
(population)
Size and composition of stockpile Uses Comment
Canada
(33M)

~ 25% of population

NAS:
50.7 M doses oseltamivir
5 M doses zanamivir
plus other federal and PT stockpiles (~80M total)

Early treatment, Rapid containment Outbreak control; Post-exposure prophylaxis in Phase 4/5 Private stockpiles may be present for pre-exposure prophylaxis
United States
(304M)

25% of population (Goal 35%)

almost all oseltamivir

Early treatment, rapid containment (prophylaxis to be covered by private stockpiling) Endorsing private stockpiling; has well-established shelf-life extension program
United Kingdom
(61M)

25% population; recent commitment to increase to 50% population (32.8M)

- two thirds oseltamivir
- one third zanamivir

Early treatment – enough for severe pandemic and small amount for pre exposure prophylaxis Post-exposure prophylaxis in households under consideration; looking at alternatives for expiring stock
France
(62M)

50% of population (may share with other EU countries)

- 240 M doses oseltamivir
- 90 M doses zanamivir

Early treatment; pre-exposure prophylaxis in Phase 4/5 Stock began to expire in 2008; looking at shelf-life extension
Japan
(127M)

23% of population, target is 45% (may share with Thailand and other Asian countries)

- 240M doses oseltamivir
- 90 M doses zanamivir

Largely early treatment Has a shelf-life extension program

Source: Global Health Security Action Group Pandemic Influenza Planning and Preparedness Survey, 2008

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