Measles & Rubella Weekly Monitoring Report: January 25 to January 31, 2015 (week 4)
Figure 1. Number of cases measles (n=4) and rubella (n=0), by week of rash onset, as reported to the Canadian Measles/ Rubella Surveillance System (CMRSS) and Measles and Rubella Surveillance system (MARS), for the period ending January 31, 2015.
During epidemiological week 04, 2015, 4 new cases of measles were reported by Ontario. Rash onset for all 4 cases occurred during week 04.
The year-to-date total is 4 cases of measles and 0 cases of rubella for 2015.
Figure 2: Distribution of confirmed measles and rubella cases by health region. Cases are included if they are considered activeFigure 2 - Footnote *
Four measles cases in Ontario reported during week 04 were genotyped. All were determined to have an identical genotype D4 strain, based on the standard N-450 sequence, that was not identical to any sequence variant found in the WHO measles sequence database (MeaNS). Extended sequencing of the H gene revealed 3 different sequences differing by 1-2 nucleotides.
Figure 3: Distribution of measles genotypes detected in 2015 (n=4) by week of rash onset (if available, n=0) or specimen collection (n=0). Epidemiological weeks are assigned in accordance with WHO guidelines (WHO.WER.2012;9(87):73) with week 1 beginning on the first Monday of the year.
The current global distribution of measles genotypes can be found on the WHO Measles Nucleotide Surveillance (MeaNS) website.
For information regarding the interpretation and use of measles genotyping (including a discussion of genotypes and sequence variants), refer to Hiebert J and Severini A. Canada Communicable Disease Report. 2014; 40-12: 257- 260.
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