Page 8: Human Antimicrobial Use Report – 2014 - Appendix B – Additional community pharmacy dispensing data
Appendix B – Additional community pharmacy dispensing data
Antimicrobial | Rank | DIRI | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amoxicillin | 1 | - | 69.11 | 75.57 | 75.90 | 76.51 | 95.43 | 100.15 | 107.32 | 121.33 | 118.57 | 118.84 | 126.57 |
Amoxicillin and enzyme inhibitor | 7 | - | 18.62 | 20.18 | 20.96 | 22.08 | 23.13 | 24.09 | 21.84 | 27.23 | 27.17 | 29.29 | 31.90 |
Azithromycin | 5 | - | 85.39 | 93.40 | 75.21 | 64.71 | 64.26 | 64.32 | 58.54 | 57.70 | 54.23 | 47.29 | 46.82 |
Cefadroxil | 23 | - | 1.97 | 2.02 | 2.28 | 2.43 | 2.58 | 2.76 | 2.50 | 2.30 | 3.15 | 3.48 | 3.97 |
Cefazolin | 24 | - | - | - | - | - | - | - | 1.78 | 1.83 | 1.52 | 2.73 | 3.15 |
Cefixime | 20 | - | 4.24 | 4.40 | 4.31 | 4.86 | 5.32 | 5.67 | 7.04 | 7.97 | 8.55 | 9.46 | 6.10 |
Cefprozil | 13 | - | 36.61 | 38.96 | 38.85 | 33.32 | 26.41 | 25.45 | 24.16 | 21.54 | 17.11 | 14.44 | 14.75 |
Ceftazidime | 33 | - | - | - | - | - | - | - | 0.48 | 0.61 | 0.41 | 0.79 | 1.26 |
Ceftriaxone | 27 | - | - | - | - | - | - | - | 0.87 | 0.99 | 1.10 | 1.98 | 2.62 |
Cefuroxime | 15 | - | 15.50 | 15.71 | 14.74 | 14.34 | 13.86 | 14.11 | 12.72 | 13.61 | 12.40 | 12.78 | 13.59 |
Cephalexin | 3 | - | 26.38 | 27.81 | 29.34 | 29.85 | 38.11 | 39.02 | 40.76 | 45.10 | 47.29 | 50.38 | 52.91 |
Ciprofloxacin | 4 | - | 85.23 | 72.50 | 72.24 | 73.76 | 74.12 | 72.26 | 74.11 | 71.15 | 63.59 | 55.85 | 52.41 |
Clarithromycin | 2 | - | 106.88 | 121.68 | 125.49 | 127.81 | 120.48 | 121.65 | 119.95 | 126.32 | 117.39 | 97.45 | 85.04 |
Clindamycin | 10 | - | 21.50 | 22.34 | 24.45 | 25.73 | 26.16 | 26.19 | 29.33 | 27.32 | 24.43 | 22.94 | 22.58 |
Cloxacillin | 21 | - | 7.20 | 6.30 | 5.97 | 5.56 | 6.67 | 6.35 | 8.24 | 6.17 | 6.12 | 5.58 | 5.12 |
Colistin | 32 | Table b.1 - Footnote * | - | - | - | - | - | - | 2.81 | 2.37 | 2.40 | 2.31 | 2.23 |
Doxycycline | 9 | - | 8.46 | 8.87 | 9.99 | 11.47 | 12.45 | 13.03 | 15.50 | 17.53 | 18.93 | 23.46 | 27.94 |
Ertapenem | 19 | Table b.1 - Footnote * | - | - | - | - | - | - | 0.61 | 1.01 | 1.33 | 5.58 | 6.56 |
Erythromycin | 28 | - | 9.39 | 8.31 | 7.92 | 6.89 | 6.22 | 5.47 | 5.42 | 4.02 | 3.57 | 2.89 | 2.46 |
Fosfomycin | 35 | Table b.1 - Footnote * | 0.18 | 0.14 | 0.11 | 0.07 | 0.01 | 0.03 | 0.02 | 0.00 | 0.02 | 0.37 | 1.09 |
Levofloxacin | 18 | - | 25.67 | 19.35 | 15.85 | 19.03 | 21.23 | 18.80 | 13.00 | 11.77 | 10.37 | 9.55 | 9.82 |
Linezolid | 22 | Table b.1 - Footnote * | 2.28 | 3.06 | 2.90 | 3.26 | 3.29 | 3.47 | 3.80 | 3.71 | 3.92 | 4.56 | 4.00 |
Meropenem | 30 | Table b.1 - Footnote * | - | - | - | - | - | - | 0.34 | 0.58 | 0.58 | 1.89 | 2.27 |
Metronidazole | 12 | - | 8.32 | 8.59 | 9.35 | 9.29 | 9.74 | 10.11 | 12.70 | 13.43 | 14.03 | 14.42 | 14.98 |
Minocycline | 11 | - | 34.75 | 35.06 | 35.30 | 34.97 | 32.59 | 30.56 | 33.05 | 30.68 | 26.60 | 23.48 | 21.62 |
Moxifloxacin | 6 | Table b.1 - Footnote * | 20.71 | 25.15 | 31.53 | 35.78 | 36.49 | 38.17 | 38.46 | 40.24 | 37.80 | 34.67 | 32.50 |
Nitrofurantoin | 8 | - | 12.88 | 13.80 | 15.36 | 16.62 | 18.29 | 20.30 | 22.70 | 25.06 | 27.36 | 28.13 | 29.81 |
Norfloxacin | 29 | - | 10.74 | 9.84 | 9.07 | 7.80 | 7.17 | 6.38 | 5.60 | 4.42 | 3.47 | 2.75 | 2.43 |
Penicillin V | 14 | - | 13.88 | 13.82 | 13.86 | 13.86 | 15.03 | 15.28 | 14.32 | 12.99 | 12.55 | 12.85 | 14.72 |
Piperacillin and tazobactam | 25 | Table b.1 - Footnote * | - | - | - | - | - | - | 1.02 | 1.42 | 0.88 | 2.77 | 3.14 |
Sulfamethoxazole and trimethoprim | 16 | - | 13.93 | 13.03 | 13.03 | 13.12 | 13.33 | 13.41 | 15.17 | 14.44 | 13.81 | 14.79 | 13.56 |
Tetracycline | 26 | - | 4.85 | 4.45 | 4.13 | 3.86 | 3.66 | 3.67 | 2.07 | 2.78 | 2.99 | 2.84 | 2.68 |
Tobramycin | 31 | Table b.1 - Footnote * | - | - | - | - | - | - | 2.24 | 2.24 | 1.81 | 1.97 | 2.27 |
Trimethoprim | 34 | - | 1.12 | 1.01 | 1.03 | 1.04 | 0.98 | 1.16 | 1.27 | 1.29 | 1.34 | 1.29 | 1.24 |
Vancomycin | 17 | - | 4.18 | 4.76 | 4.60 | 5.25 | 5.46 | 5.96 | 8.98 | 11.06 | 11.17 | 12.12 | 12.28 |
TOTAL | 0 | - | 678.70 | 698.42 | 679.96 | 672.68 | 689.00 | 692.79 | 712.76 | 735.79 | 701.25 | 680.54 | 681.63 |
Antimicrobial | Rank | DIRI | BC | AB | SK | MB | ON | QC | NB | NS | PEI | NF |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Amoxicillin | 1 | - | 13854.3 | 16686.8 | 5457.0 | 4698.2 | 54249.4 | 22147.5 | 2493.2 | 3341.3 | 478.1 | 3166.1 |
Amoxicillin and enzyme inhibitor | 7 | - | 3483.7 | 4575.5 | 1015.9 | 1645.0 | 9660.5 | 8895.0 | 692.1 | 824.6 | 271.8 | 836.7 |
Azithromycin | 5 | - | 3127.0 | 5008.7 | 2178.4 | 2600.4 | 20145.0 | 10632.3 | 976.6 | 885.3 | 206.2 | 1059.2 |
Cefadroxil | 23 | - | 19.4 | 49.9 | 0.2 | 1.1 | 100.6 | 3770.1 | 26.6 | 0.9 | 0.1 | 0.0 |
Cefazolin | 24 | - | 5.6 | 100.2 | 32.2 | 4.4 | 68.7 | 2660.6 | 106.5 | 167.3 | 1.5 | 0.8 |
Cefixime | 20 | - | 967.0 | 1281.2 | 74.4 | 112.5 | 2092.2 | 1140.2 | 100.8 | 138.9 | 40.9 | 147.0 |
Cefprozil | 13 | - | 84.8 | 1080.6 | 99.6 | 340.5 | 7100.0 | 5483.1 | 190.8 | 347.3 | 13.0 | 9.9 |
Ceftriaxone | 27 | - | 130.9 | 68.5 | 35.3 | 8.3 | 451.3 | 1674.1 | 113.4 | 113.3 | 8.2 | 16.0 |
Cefuroxime | 15 | - | 2354.1 | 1191.1 | 380.6 | 275.1 | 5129.6 | 2018.1 | 885.2 | 618.5 | 34.5 | 706.7 |
Cephalexin | 3 | - | 8665.6 | 8866.8 | 3441.4 | 3018.1 | 20170.5 | 3651.9 | 1421.1 | 1872.1 | 301.1 | 1500.6 |
Ciprofloxacin | 4 | - | 6383.0 | 5569.4 | 1672.2 | 1656.0 | 16362.4 | 16757.9 | 882.8 | 1306.6 | 186.6 | 1632.8 |
Clarithromycin | 2 | - | 9109.8 | 11039.9 | 2212.3 | 1894.4 | 30645.8 | 24012.0 | 1747.2 | 2346.8 | 352.3 | 1678.9 |
Clindamycin | 10 | - | 2510.6 | 2959.3 | 1102.2 | 1066.3 | 7292.7 | 6004.8 | 561.1 | 658.9 | 66.9 | 358.9 |
Cloxacillin | 21 | - | 767.1 | 741.9 | 324.9 | 328.7 | 1479.3 | 897.4 | 154.3 | 179.3 | 31.8 | 213.3 |
Colistin | 32 | Table b.2 - Footnote * | 291.4 | 43.3 | 47.3 | 83.7 | 41.6 | 1505.4 | 109.9 | 55.5 | 0.0 | 47.5 |
Doxycycline | 9 | - | 4974.6 | 3822.1 | 1830.6 | 864.5 | 9949.6 | 4386.7 | 551.7 | 1009.5 | 133.4 | 418.7 |
Ertapenem | 19 | Table b.2 - Footnote * | 9.7 | 109.1 | 0.0 | 0.6 | 51.8 | 6118.5 | 43.7 | 221.6 | 0.0 | 0.4 |
Erythromycin | 28 | - | 531.8 | 293.0 | 246.5 | 141.3 | 792.9 | 175.3 | 56.0 | 116.2 | 46.9 | 64.3 |
Levofloxacin | 18 | - | 374.1 | 1394.5 | 128.6 | 904.0 | 4249.6 | 2256.6 | 150.8 | 290.9 | 27.2 | 45.6 |
Linezolid | 22 | Table b.2 - Footnote * | 433.3 | 416.5 | 156.1 | 107.7 | 984.1 | 1820.3 | 22.4 | 24.1 | 11.7 | 24.8 |
Meropenem | 30 | Table b.2 - Footnote * | 1.1 | 10.3 | 0.0 | 1.7 | 35.8 | 2144.4 | 60.9 | 19.5 | 0.0 | 0.0 |
Metronidazole | 12 | - | 1789.1 | 2068.7 | 576.1 | 447.8 | 6295.5 | 2485.6 | 334.1 | 477.0 | 59.3 | 449.2 |
Minocycline | 11 | - | 2412.1 | 3153.8 | 223.8 | 872.5 | 7308.6 | 6345.5 | 350.9 | 615.5 | 54.5 | 284.8 |
Moxifloxacin | 6 | Table b.2 - Footnote * | 4082.2 | 2158.8 | 822.4 | 507.3 | 11519.3 | 11495.8 | 751.0 | 554.7 | 140.2 | 466.3 |
Nitrofurantoin | 8 | - | 5044.7 | 3371.3 | 1436.3 | 783.7 | 13857.3 | 2957.9 | 670.5 | 1104.5 | 120.7 | 459.5 |
Norfloxacin | 29 | - | 45.3 | 210.8 | 7.1 | 20.5 | 1729.5 | 77.0 | 187.5 | 53.8 | 14.6 | 82.3 |
Penicillin V | 14 | - | 1867.0 | 1980.4 | 381.1 | 508.2 | 4729.8 | 4205.5 | 377.3 | 408.0 | 64.7 | 193.5 |
Piperacillin and tazobactam | 25 | Table b.2 - Footnote * | 0.0 | 14.9 | 1.2 | 0.7 | 8.1 | 2968.6 | 122.9 | 27.6 | 0.0 | 0.0 |
Sulfamethoxazole and trimethoprim | 16 | - | 1855.9 | 1636.8 | 791.7 | 694.8 | 5088.6 | 2036.6 | 387.3 | 606.6 | 86.4 | 370.8 |
Tetracycline | 26 | - | 348.5 | 194.3 | 79.1 | 105.8 | 1547.9 | 219.6 | 40.4 | 71.3 | 19.6 | 52.3 |
Tobramycin | 31 | Table b.2 - Footnote * | 84.1 | 82.4 | 43.3 | 75.0 | 448.9 | 1074.9 | 157.4 | 175.6 | 12.3 | 112.6 |
Vancomycin | 17 | - | 728.0 | 963.4 | 153.2 | 85.3 | 1942.8 | 7413.3 | 379.6 | 523.7 | 24.6 | 69.7 |
TOTAL | 0 | - | 77193.4 | 81787.3 | 25130.8 | 23914.4 | 247507.0 | 173798.5 | 15347.2 | 19445.4 | 2823.9 | 14678.3 |
Antimicrobial | RankTable b.3 - Footnote * | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Amoxicillin | 1 | 49490 | 51633 | 52365 | 52454 | 53918 | 55135 | 57436 | 62975 | 61390 | 61745 | 65426 |
Amoxicillin and enzyme inhibitor | 3 | 7478 | 8399 | 8941 | 9755 | 10523 | 10999 | 9670 | 12903 | 13886 | 15435 | 17108 |
Azithromycin | 11 | 2670 | 2915 | 2876 | 2802 | 2869 | 2915 | 2880 | 3813 | 3828 | 3253 | 3304 |
Cefadroxil | 20 | 707 | 730 | 821 | 875 | 926 | 983 | 874 | 779 | 1049 | 1151 | 1315 |
Cefazolin | 22 | - | - | - | - | - | - | 161 | 236 | 286 | 1017 | 972 |
Cefprozil | 12 | 4377 | 4589 | 4536 | 4183 | 4109 | 4095 | 4092 | 4188 | 3695 | 3328 | 3246 |
Cefuroxime | 13 | 2677 | 2741 | 2606 | 2597 | 2573 | 2603 | 2265 | 2567 | 2505 | 2696 | 2868 |
Cephalexin | 2 | 19626 | 20877 | 22183 | 22502 | 23148 | 22660 | 22409 | 24285 | 24894 | 25903 | 26339 |
Ciprofloxacin | 5 | 12627 | 12952 | 13827 | 14436 | 14702 | 14280 | 14750 | 15229 | 14860 | 14243 | 13870 |
Clarithromycin | 6 | 12731 | 14498 | 15258 | 16133 | 16560 | 16943 | 16734 | 17641 | 16755 | 14578 | 13185 |
Clindamycin | 8 | 4447 | 4504 | 4983 | 5310 | 5558 | 5570 | 6162 | 6183 | 6130 | 6159 | 6198 |
Cloxacillin | 14 | 6604 | 5868 | 5612 | 5165 | 4780 | 4383 | 5495 | 4040 | 3565 | 3073 | 2698 |
Doxycycline | 17 | 820 | 864 | 930 | 1028 | 1117 | 1165 | 1397 | 1543 | 1658 | 1791 | 1945 |
Erythromycin | 21 | 5223 | 4446 | 3961 | 3423 | 3297 | 2700 | 2554 | 1759 | 1653 | 1382 | 1183 |
Levofloxacin | 19 | 1878 | 1678 | 1536 | 1474 | 1484 | 1425 | 1349 | 1392 | 1361 | 1378 | 1449 |
Metronidazole | 7 | 5238 | 5311 | 5564 | 5588 | 5789 | 5921 | 6347 | 6393 | 6527 | 6644 | 6874 |
Minocycline | 16 | 2396 | 2430 | 2470 | 2441 | 2463 | 2345 | 2543 | 2454 | 2218 | 2102 | 1955 |
Moxifloxacin | 18 | 1231 | 1478 | 1828 | 2046 | 2049 | 2094 | 2076 | 2133 | 1971 | 1786 | 1664 |
Nitrofurantoin | 15 | 1152 | 1211 | 1324 | 1390 | 1503 | 1625 | 1740 | 1862 | 1975 | 1992 | 2076 |
Penicillin V | 9 | 7843 | 8046 | 8003 | 7852 | 7618 | 7511 | 6963 | 6131 | 5850 | 5434 | 5257 |
Sulfamethoxazole and trimethoprim | 4 | 20518 | 18891 | 18554 | 18129 | 18177 | 18234 | 18212 | 18103 | 16928 | 16737 | 16712 |
Tetracycline | 10 | 7829 | 7410 | 6871 | 6221 | 5840 | 5746 | 3125 | 3922 | 4105 | 3849 | 3625 |
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