Canada Communicable Disease Report

June 2008

Volume 34
Number 06

Monthly Report

Information Update on Currently Approved Vaccines

The information appearing in Table 1. Type and Contents of Vaccines Currently Approved for Use in Canada, on pages 7 to 16 of the Canadian Immunization Guide, 7th edition, has been updated since May 2006. Revisions have been made to reflect the current content in product monographs, and information on newly-approved vaccines has been added. The updated table may also be accessed through the Public Health Agency of Canada’s webpages for the National Advisory Committee on Immunization (www.naci.gc.ca) and for the Canadian Immunization Guide (http://www.phac-aspc.gc.ca/publicat/cig-gci/index-eng.php). Since the information in the table below is based on the product’s availability as of March 2008, please consult the manufacturer for complete and up-to-date information.


Table 1. Type and Contents of Vaccines Currently Approved for Use in Canada

Brand name Mfr/distr. Route Vaccine type Adjuvant Preser-
vative
Potential allergens (egg, antibiotic, gelatin, latex) Other materials
Vaccine type Immunogen+ Products
Act-HIB® SP IM Subunit Hib Conjugate

 

 

 

 

ActacelTM* SP IM Subunit D, T, aP + (Hib) Proteins + Conjugate Alum PE  
Adacel® SP IM Subunit T, d, ap Proteins Alum PE
Avaxim® SP IM Inactivated HA Killed virus Alum PE Neomycin Formaldehyde
Avaxim® - Pediatric SP IM Inactivated HA Killed virus Alum PE Neomycin Formaldehyde
BCG Vaccine (Freeze-Dried) SP Intra -dermal Live attenuated BCG Live bacteria Polysorbate 80
Boostrix®* GSK IM Subunit T, d, ap Proteins Alum PE Latex in plunger stopper of prefilled syringe Formaldehyde
DT Polio Adsorbed SP IM Subunit + inactivated D, T, IPV Proteins + killed virus Alum PE Polymyxin B Neomycin Formaldehyde
DukoralTM SBL/SP Oral Subunit + inactivated Chol-Ecol-O Proteins + killed bacteria Saccharin
Multi dose vialEngerix®-B Single dose vial GSK IM Subunit HB Recombinant protein Alum PE Yeast protein
EolarixTM* GSK SC Live M, R Live virus Neomycin Human albumin Lactose Dextran
Epaxal®** BERN IM Inactivated HA in Inf virosome Killed virus Tm Formaldehyde
Fluviral® S/F GSK IM Inactivated Inf Killed virus Tm Egg proteins Formaldehyde
FSME - IMMUN® BAX IM Inactivated TBE Inactivated whole virus Alum Neomycin Gentamycin Protamine sulfate Residual components of chick embryo cell cultures Formaldehyde Human serum albumin Sucrose
GardasilTM MF Subunit HPV Recombinant protein Alum Polysorbate 80 Yeast protein
Havrix® GSK IM Inactivated HA Killed virus Alum PE Neomycin Latex in plunger stopper of pre-filled syringes Formaldehyde Polysorbate 20
Hiberix®* GSK IM Subunit Hib Conjugate Lactose
Imovax® Polio* SP SC Inactivated IPV Killed virus PE Polymyxin B Neomycin Streptomycin Bovine serum Formaldehyde Polysorbate 80
Imovax® Rabies SP IM Inactivated Rab Killed virus Neomycin Human albumin
Inactived Poliomyelitis Vaccine – IPV SP SC Inactivated IPV Killed virus PE Polymyxin B Neomycin Bovine serum Formaldehyde Polysorbate 80
InfanrixTM* GSK IM Subunit D, T, aP Proteins Alum PE Latex in plunger stopper of prefilled syringe Formaldehyde
InfanrixTM-hexa* GSK IM Subunit + inactivated D, T, aP, HB, IPV + (Hib) Proteins + killed viruses + conjugate Alum PE Polymyxin B Neomycin Latex in plunger stopper of prefilled syringe Yeast protein Formaldehyde Lactose Polysorbate 20 and 80
InfanrixTM/Hib* GSK IM Subunit D, T, aP + (Hib) Proteins + conjugate Alum PE Latex in plunger stopper of prefilled syringe Formaldehyde Lactose
InfanrixTM-IPV* GSK IM Subunit + inactivated D, T, aP, IPV Proteins + killed virus Alum PE Polymyxin B Neomycin Latex in plunger stopper of prefilled syringes Formaldehyde Polysorbate 80
InfanrixTM -IPV/Hib* GSK IM Subunit + inactivated D, T, aP, IPV + (Hib) Proteins + killed virus + conjugate Alum PE Polymyxin B Neomycin Latex in plunger stopper of prefilled syringe Formaldehyde Polysorbate 80 Lactose
InfluvacTM SOLV IM/SC Inactivated Inf Killed virus Gentamicin Egg protein Chicken protein Formaldehyde Polysorbate 80
JE-VAX® BIKEN/SP SC Inactivated JE Killed virus Tm Gelatin Mouse serum protein Formaldehyde
Liquid Pedvax HIB® MF IM Subunit Hib Conjugate Alum Latex in stopper
MenactraTM SP IM Subunit Men Conjugate Latex in stopper of vial Syringes are latex free
MeningitecTM BERN/WA IM Subunit Men Conjugate Alum Latex in stopper of vial and plunger stopper of prefilled syringe

Empty boxes indicate a lack of the specified component.
* Drug Identification Number assigned (approved for use but not currently marketed)
** Product is on the market but not currently available
† Thimerosal in multidose vial only

Notes and Abbreviations

The information in this table is based on the product’s availability as of May 2006. Please consult the manufacturer for complete and up-to-date information. The National Advisory Committee on Immunization (NACI) will publish updated information as required, which will be available at www.naci.gc.ca.

Manufacturer (Mfr) and Distributor (Distr.): For some products, the distributor could be different from the manufacturer.

BAX – Baxter Healthcare Corporation; BERN – Berna Biotech; BIKEN – Biken; GSK – GlaxoSmithKline; IDB – ID Biomedical Corporation; MF – Merck Frosst; NOV – Novartis Vaccines and Diagnostics; SBL – SBL Vaccine; SP – Sanofi Pasteur Ltd; SOLV – Solvay; WA – Wyeth Canada

Route: IM – intramuscular; SC – subcutaneous

Immunogen:

+ For products in which the immunogens of two different vials or chambers are combined, the contents of the second vial or chamber are noted as + (immunogen)

The following abbreviations are the agreed upon standards for use in Canada:

BCG – Bacillus Calmette Guérin; Chol-Ecol-O – cholera-E.coli-oral; DTaP-IPV-Hib – diphtheria toxoid, tetanus toxoid, acellular pertussis, polio, Haemophilus influenzae type b, pediatric formulation; HA – hepatitis A; HB – hepatitis B; Inf – influenza; IPV – inactivated poliomyelitis virus; JE – Japanese encephalitis; Men – meningococcus; MMR – measles, mumps, rubella; Pneu – pneumococcus; Rab – rabies; TBE – tickborne encephalitis; Tdap – tetanus toxoid, diphtheria toxoid, acellular pertussis, adult formulation; Typh-I – typhoid-injection; Typh-O – typhoid-oral; Var – varicella; YF – yellow fever

Adjuvant: Alum – aluminum-containing adjuvant

Preservative:

P – phenol; PE – 2 phenoxy ethanol; Tm – thimerosal. For the Sanofi Pasteur products, PE is not considered a preservative.

Report a problem or mistake on this page
Please select all that apply:

Thank you for your help!

You will not receive a reply. For enquiries, contact us.

Date modified: