ARCHIVED - Canadian Recommendations for the Prevention and Treatment of Malaria Among International Travellers - 2009



June 2009 Volume 35S1
PDF Version (723 KB)

Contained in this issue:

Table of Contents

  1. Introduction
  2. Prevention - Risk Assessment
    1. Risk of Acquiring Malaria
    2. Exposure Assessment
    3. Host Assessment
  3. Prevention - Malaria Education for Travellers
    1. Traveller Behaviour Modification/Education
      • Enhancing adherence to antimalarial chemoprophylaxis and personal protective measures
      • Early diagnosis and treatment
    2. Insect Repellants and Clothing
    3. Insecticide-Treated Bednets
  4. Prevention - Chemoprophylactic Regimens
    1. Selection of Antimalarial Drugs for Individual Travellers
    2. Selection of Antimalarial Drugs for Specific Regions
      • Urban and rural areas
      • Rural areas
      • Chloroquine-sensitive regions
      • Chloroquine-resistant regions
      • Choroquine- and mefloquine-resistant regions
    3. Primaquine Terminal Prophylaxis for Prevention of Relapses of P. vivax and P. ovale
    4. Differences in Approaches to Malaria Chemoprophylaxis in Other Jurisdictions
    5. Coadministration of Antimlarial Drugs with Vaccines
  5. Prevention in Special Hosts
    1. Malaria Prevention in Children
    2. Malaria Prevention in Pregnancy
    3. Prophylaxis while Breast-feeding
    4. Malaria Prevention in the Long-Term Traveller or Expatriate
      • Adverse events
      • Current malaria prevention practice among expatriates
      • Support for established guidelines
      • Insecticide-treated bednets
      • Rapid diagnostic tests (RDTs)
      • Counterfeit drugs
      • Terminal prophylaxis
    5. Malaria Prevention in Travellers with Co-morbidities
      • Immunocompromised hosts
      • Other conditions
  6. Malaria Diagnosis
    1. Rapid Diagnostic Tests
    2. Polymerase Chain Reaction (PCR)
  7. Treatment of Malaria
    1. General Principles of Management
    2. Management of Falciparum Malaria
      • Severe malaria
      • Uncomplicated P. Falciparum
    3. Management of Non-Falciparum Malaria (P. vivax, P. ovale, P. malariae)
    4. Management of Malaria When Laboratory Results or Treatment Drugs Are Delayed
    5. Primaquine Treatment
    6. Self-treatment of Presumptive Malaria
  8. Drugs for the Prevention and treatment of Malaria
    1. Artemisin and Derivatives
    2. Atovaquone/Proguanil (ATQ/PG)
    3. Chloroquine (or Hydroxychloroquine)
    4. Clindamycin
    5. Doxycycline
    6. Mefloquine
    7. Primaquine
    8. Quinine and Quinadine
    9. Other Drugs Not Available Or Not Routinely Recommended in Canada

Appendix I. Malaria Risk by Geographic Area in Countries with Endemic Malaria (2008)

Appendix II. Checklist for Advising Travellers to Malarial Areas

Appendix III. Frequently Asked Questions (FAQs) About Malaria

Appendix IV. Strength and Quality of Evidence Summary

Appendix V. Canadian Malaria Network: Accessing Parenteral Artesunate or Quinine

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