Guidelines for Canadian recreational water quality: Microbiological pathogens and biological hazards: References

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Abe, C.M., Salvador, F.A., Falsetti, I.N., Vieira, M.A.M., Blanco, J., Blanco, J.E., Blanco, M., Machado, A.M.O., Elias, W.P., Hernandes, R.T., and Gomes, T.A.T. (2008). Uropathogenic Escherichia coli (UPEC) strains may carry virulence properties of diarrhoeagenic E. coli. FEMS Immunol. Med. Microbiol., 52: 397–406.

Adjemian, J., Daniel-Wayman, S., Ricotta, E., and Prevots, D.R. (2018). Epidemiology of nontuberculous mycobacteriosis. Semin, Respir, Crit. Care Med., 39(3): 325–335.

Andino, A., and Hanning, I. (2015). Salmonella enterica: survival, colonization, and virulence differences among serovars. Sci. World J., 2015: 520179.

Allegra, S., Berger, F., Berthelot, P., Grattard, F., Pozzetto, B., and Riffard, S. (2008). Use of flow cytometry to monitor Legionella viability. Appl. Environ. Microbiol., 74 (24):7813–7816.

AWWA (1999). Waterborne pathogens. AWWA manual of water supply practices M48. American Water Works Association, Denver, CO.

AWWA (2006). Waterborne pathogens. AWWA manual of water supply practices M48. Second edition. American Water Works Association, Denver, CO.

Backert, S., Tegtmeyer, N., Ó Cróinín, T., Boehm, M., and Heimesaat, M.M. (2017). Human campylobacteriosis. In: Campylobacter – Features, Detection, and Prevention of Foodborne Disease. Klein, G. (ed.), Elsevier Inc.

Barragan, V., Olivas, S., Keim, P., and Pearson, T. (2017). Critical knowledge gaps in our understanding of environmental cycling and transmission of Leptospira spp. Appl. Environ. Microbiol., 83: e01190-17.

Bartrand, T.A., Causey, J.J., and Clancy, J.L. (2014). Naegleria fowleri: An emerging drinking water pathogen. J. Am. Water Works Assoc., 106(10): E418-E432.

Barwick, R.S., Levy, D.A., Craun, G.F., Beach, M.J., and Calderon, R.L. (2000). Surveillance for waterborne-disease outbreaks—United States, 1997–1998. MMWR CDC Surveill. Summ., 49: 1–21.

Berrilli, F., Di Cave, D., De Liberato, C., Franco, A., Scaramozzino, P., and Orecchia, P. (2004). Genotype characterisation of Giardia duodenalis isolates from domestic and farm animals by SSU-rRNA gene sequencing. Vet. Parasitol., 122(3):193–199.

Bhowmick, U.D., and Bhattacharjee, S. (2018). Bacteriological, clinical and virulence aspects of Aeromonas-associated diseases in humans. Pol. J. Microbiol., 67(2): 137–149.

Boarato-David, E., Guimarães, S., and Cacciò, S. (2017). Giardia duodenalis. In: J.B., Rose and B., Jiménez-

Cisneros (eds.), Global Water Pathogen Project. (R. Fayer and W. Jakubowski,

(eds) Part 3 Protists) Michigan State University, E.

Lansing, MI, UNESCO.

Bosch, A., Guix, S., Sano, D., and Pinto, R.M. (2008). New tools for the study and direct surveillance of viral pathogens in water. Curr. Opin. Biotechnol., 19(3): 295–301.

Bosch, A., Pintó, R.M., and Guix, S. (2014). Human astroviruses. Clin. Microbiol. Rev., 27(4): 1048–1074.

British Columbia Ministry of Health (2018). Swimmer’s itch. HealthLink BC File No. 52, October 2018.

Bruneau, A., Rodrigue, H., Ismael, J., Dion, R., and Allard, R. (2004). Outbreak of E. coli O157:H7 associated with bathing at a public beach in the Montreal-Centre region. Can. Commun. Dis. Rep., 30: 133–136.

Burillo, A., Pedro-Botet, M.L., and Bouza, E. (2017). Microbiology and epidemiology of Legionnaires’ disease. Infect. Dis. Clin. North Am., 31(1): 7–27.

Butler, A.J., Thomas, M.K., and Pintar, K.D.M. (2015). Expert elicitation as a means to attribute 28 enteric pathogens to foodborne, waterborne, animal contact, and person-to-person transmission routes in Canada. Foodborne Pathog. Dis., 12(4): 335–344.

Calderon, R.L., Mood, E.W., and Dufour, A.P. (1991). Health effects of swimmers and nonpoint sources of contaminated water. Int. J. Environ. Health Res., 1: 21–31.

Candy, D.C. (2007). Rotavirus infection: A systemic illness? PLoS Med., 4(4): e117.

Cangelosi, G., Clark-Curtiss, J., Behr, M., Bull, T., and Stinear, T. (2004). Biology of waterborne pathogenic mycobacteria. In: Pathogenic mycobacteria in water: a guide to public health consequences, monitoring and management. IWA Publishing. World Health Organization. Geneva, Switzerland. pp. 39–54.

Cann, K.F., Thomas, D.R., Salmon, R.L., Wyn-Jones, A.P., and Kay, D. (2013). Extreme water-related weather events and waterborne disease. Epidemiol. Infect. 141: 671–686.

Capewell, L.G., Harris, A.M., Yoder, J.S., Cope, J.R., Eddy, B.A., Roy, S.L., Visvesvara, G.S., Fox, L.M., and Beach, M.J. (2015). Diagnosis, clinical course, and treatment of primary amoebic meningoencephalitis in the United States, 1937-2013. J. Pediatric Infect. Dis. Soc., 4(4): e68-e75.

Carter, M.J. (2005). Enterically infecting viruses: Pathogenicity, transmission and significance for food and waterborne infection. J. Appl. Microbiol., 98(6): 1354–1380.

Caul, E.O. (1996). Viral gastroenteritis: Small round structured viruses, caliciviruses and astroviruses. Part II. The epidemiological perspective. J. Clin. Pathol., 49(12): 959–964.

CCME (1999). Canadian environmental quality guidelines. Canadian Council of Ministers of the Environment.

CDC (2004a). Parasites and health: cercarial dermatitis. DPDx Laboratory Identification of Parasites of Public Health Concern. Centres for Disease Control and Prevention, Atlanta, Georgia.

CDC (2004b). Parasitic disease information – fact sheet: cercarial dermatitis. Division of Parasitic Diseases. Centers for Disease Control and Prevention, Atlanta, Georgia.

CDC (2005a). Shigellosis. Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, United States Department of Health and Human Services, Atlanta, Georgia. Available at:

CDC (2005b). Leptospirosis. Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, United States Department of Health and Human Services, Atlanta, Georgia. Available at:

CDC (2008). Surveillance for Waterborne Disease and Outbreaks Associated with Recreational Water Use and Other Aquatic Facility-Associated Health Events — United States, 2005–2006 and Surveillance for Waterborne Disease and Outbreaks Associated with Drinking Water and Water Not Intended for Drinking — United States, 2005–2006. Surveillance Summaries. MMWR 2008;57 (no. SS-9).

CDC (2013a). Antibiotic Resistance Threats in the United States, 2013.

CDC (2013b). Norovirus clinical overview. Available at:

CDC (2015). Viral hepatitis – hepatitis A information. Available at

CDC (2019). Parasites — Naegleria fowleri — Primary Amebic Meningoencephalitis (PAM) — Amebic Encephalitis. General Information. Centers for Disease Control and Prevention. Atlanta, GA. [accessed July 2019].

CDC (2020). Surveillance reports for recreational water-associated disease & outbreaks. Atlanta, GA: US Department of Health and Human Services, CDC. Available at:

CDC (2021b). Parasites – Acanthamoeba – Granulomatous Amebic Encephalitis (GAE); Keratitis. Center for Disease Control and Prevention, Atlanta, GA. [accessed July 2021].

CDC (2021c). Parasites – Cryptosporidium (also known as “Crypto”). Illness & Symptoms. Center for Disease Control and Prevention, Atlanta, GA. [accessed May 2021].

Cervero-Aragó, S., Rodríguez-Martínez, S., Puertas-Bennasar, A., and Araujo, R.M. (2015). Effect of common drinking water disinfectants, chlorine and heat, on free Legionella and amoebae-associated Legionella. PLoS ONE, 10 (8), art. no. e0134726.

Cervero-Aragó, S., Schrammel, B., Dietersdorfer, E., Sommer, R., Lück, C., Walochnik, J., and Kirschner, A. (2019). Viability and infectivity of viable but nonculturable Legionella pneumophila strains induced at high temperatures. Water Res., 158: 268–279.

Chakravarty, S. and Anderson, G.G. (2015). The genus Pseudomonas. In: Practical handbook of microbiology. Goldman, E. and Green, L.H. (eds.). Third edition. CRC Press, Taylor & Francis Group, Boca Raton, FL., pp. 321–343.

Chalmers, R.M. (2014a). Acanthamoeba. In: Microbiology of waterborne diseases: Microbiological aspects and risks. Second edition. Elsevier Ltd., Oxford, UK, pp. 263–276.

Chalmers, R.M. (2014b). Naegleria. In: Microbiology of waterborne diseases: Microbiological aspects and risks: Second edition. Elsevier Ltd., Oxford, UK, pp. 407–416.

Chambers, P.A., Guy, M., Roberts, E.S., Charlton, M.N., Kent, R., Gagnon, C., Grove, G., and Foster, N. (2001). Nutrients and their impact on the Canadian environment. Agriculture and Agri-Food Canada, Environment Canada, Fisheries and Oceans Canada, Health Canada and Natural Resources Canada. 241 pp.

Chappell, C.L., Okhuysen, P.C., Sterling, C.R., Wang, C., Jakubowski, W., and Dupont, H.L. (1999). Infectivity of Cryptosporidium parvum in healthy adults with pre-existing anti-C. parvum serum immunoglobulin G. Am. J. Trop. Med. Hyg., 60(1): 157–164.

Chappell, C.L., Okhuysen, P.C., Langer-Curry, R., Widmer, G., Akiyoshi, D.E., Tanriverdi, S., and Tzipori, S. (2006). Cryptosporidium hominis: experimental challenge of healthy adults. Am. J. Trop. Med. Hyg., 75(5):851–857.

Chapron, C.D., Ballester, N.A., Fontaine, J.H., Frades, C.N., and Margolin, A.B. (2000). Detection of astroviruses, enteroviruses, and adenovirus types 40 and 41 in surface waters collected and evaluated by the information collection rule and an integrated cell culture-nested PCR procedure. Appl. Environ. Microbiol., 66: 2520–2525.

Charoenca, N. and Fujioka, R. (1995). Association of staphylococcal skin infections and swimming. Water Sci. Technol., 31: 11–18.

Cheetham, S., Souza, M., McGregor, R., Meulia, T., Wang, Q., and Saif, L.J. (2007). Binding patterns of human norovirus-like particles to buccal and intestinal tissues of gnotobiotic pigs in relation to A/H histo-blood group antigen expression. J. Virol., 81(7): 3535–3544.

City of Hamilton (2020). Public Health responding to E. coli outbreak at Valens Lake Conservation Area. City of Hamilton News Releases. Available at:

Cliver, D.O. and Moe, C.L. (2004). Prospects of waterborne viral zoonoses. In: Waterborne zoonoses: identification, causes, and control. Cotruvo, J.A., Dufour, A., Rees, G., Bartram, J., Carr, R., Cliver, D.O., Craun, G.F., Fayer, R., and Gannon, V.P.J. (eds.). IWA Publishing, London, UK, pp. 242–254.

Chia, J.K. and Chia, A.Y. (2008). Chronic fatigue syndrome is associated with chronic enterovirus infection of the stomach. J. Clin. Pathol., 61(1): 43–48.

Cope, J.R. and Ali, I.K. (2016). Primary Amebic Meningoencephalitis: What have we learned in the last 5 years? Curr. Infect. Dis. Rep., 18: 31.

Corsi, S.R., Borchardt, M.A., Spencer, S.K., Hughes, P.E., and Baldwin, A.K. (2014). Human and bovine viruses in the Milwaukee River watershed: Hydrologically relevant representation and relations with environmental variables. Sci. Total Environ., 490: 849–860.

Cotton, J.A., Beatty, J.K., and Buret, A.G. (2011). Host parasite interactions and pathophysiology in Giardia infections. Int. J. Parasitol., 41(9):925–933.

Crabtree, K.D., Gerba, C.P., Rose, J.B., and Haas, C.N. (1997). Waterborne adenovirus: a risk assessment. Water Sci. Technol., 35: 1–6.

Croxen, M.A., Law, R.J., Scholz, R., Keeney, K.M., Wlodarska, M., and Finlay, B.B. (2013). Recent advances in understanding enteric pathogenic Escherichia coli. Clin. Microbiol. Rev., 26(4): 822-880.

David, M.Z., and Daum, R.S. (2010). Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic. Clin. Microbiol. Rev., 23(3): 616–687.

Davies, R.B., and Hibler, C.P. (1979). Animal reservoirs and cross-species transmission of Giardia. In: Waterborne transmission of giardiasis. Jakubowski, W.and Hoff, J.C. (eds.). EPA 600/9-79-001, United States Environmental Protection Agency, Cincinnati, OH, pp. 104–126.

De Groote, M.A. (2004). Disease resulting from contaminated equipment and invasive procedures. In: Pathogenic mycobacteria in water – A guide to public health consequences, monitoring and management. S. Pedley et al. (eds). World Health Organization, Geneva, Switzerland. pp: 131-142.

de Lacerda, A.G., and Lira, M. (2021). Acanthamoeba keratitis: a review of biology, pathophysiology and epidemiology. Ophthalmic Physiol. Opt., 41: 116–135.

Degnan, A.J. (2006). Chapter 16: Pseudomonas. In: Waterborne pathogens. AWWA manual of water supply practices M48.. Second edition. American Water Works Association, Denver, CO, pp. 131–134.

Denis-Mize, K., Fout, G.S., Dahling, D.R., and Francy, D.S. (2004). Detection of human enteric viruses in stream water with RT-PCR and cell culture. J. Water Health, 2(1): 37–47.

Denno, D.M., Keene, W.E., Hutter, C.M., Koepsell, J.K, Patnode, M., Flodin-Hursh, D., Stewart, L.K., Duchin, J.S., Rasmussen, L., Jones, R., and Tarr, P.I. (2009). Tri-county comprehensive assessment of risk factors for sporadic reportable bacterial enteric infection in children. J. Infect. Dis., 199: 467–476.

Dorevitch, S., Dworkin, M.S., DeFlorio, S.A., Janda, W.M., Wuellner, J., and Hershaw, R.C. (2012). Enteric pathogens in stool samples of Chicago-area water recreators with new onset gastrointestinal symptoms. Water Res., 46: 4961–4972.

Dufour, A., Wade, T.J., and Kay D. (2012). Epidemiological studies on swimmer health effects associated with potential exposure to zoonotic pathogens in bather beach water – a review. In: Animal Waste, Water Quality and Human Health. Dufour, A., Bartram, J., Bos, R., and Gannon, V. IWA Publishing, London, UK.

DuPont, H.L., Chappell, C.L., Sterling, C.R., Okhuysen, P.C., Rose, J.B., and Jakubowski, W. (1995). The infectivity of Cryptosporidium parvum in healthy volunteers. N. Engl. J. Med., 332: 855–859.

Economy, L.M., Wiegner, T.N., Strauch, A.M., Awaya, J.D., and Gerken, T. (2019). Rainfall and streamflow effects on estuarine Staphylococcus aureus and fecal indicator bacteria concentrations. J. Environ. Qual., 48: 1711–1721.

Edelstein, P.H., and Roy, C.R. (2015). Legionnaires' disease and Pontiac fever. In: Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Bennett, J.E. et al. (eds.). Saunders. Philadelphia, PA. pp. 2633-2644.

Edge, T.A., Khan, I.U.H., Bouchard, R., Guo, J., Hill, S., Locas, A., Moore, L., Neumann, N., Nowak, E., Payment, P., Yang, R., Yerubandi, R., and Watson, S. (2013). Occurrence of waterborne pathogens and Escherichia coli at offshore drinking water intakes in Lake Ontario. Appl. Environ. Microbiol., 79(19): 5799–5813.

Eligio-García, L., Cortes-Campos, A., and Jiménez-Cardoso, E. (2005). Genotype of Giardia intestinalis isolates from children and dogs and its relationship to host origin. Parasitol. Res., 97(1):1–6.

Englebert, E.T., McDermott, C., and Kleinheinz, G.T. (2008). Effects of the nuisance algae, Cladophora, on Escherichia coli at recreational beaches in Wisconsin. Sci. Total. Environ., 404:10–17.

Eregno, F.E., Tryland, I., Tjomsland, T., Myrmel, M., Robertson, L., and Heistad, A. (2016). Quantitative microbial risk assessment combined with hydrodynamic modelling to estimate the public health risk associated with bathing after rainfall events. Sci. Total Environ., 548-549: 270–279.

Erlandsen, S.L., Sherlock, L.A., Januschka, M., Schupp, D.G., Schaefer, F.W. III, Jakubowski, W., and Bemrick, W.J. (1988). Cross-species transmission of Giardia spp.: inoculation of beavers and muskrats with cysts of human, beaver, mouse, and muskrat origin. Appl. Environ. Microbiol., 54(11): 2777–2785.

Estes, M.K., and Greenberg, H.B. (2013). Rotaviruses. In: Fields virology. Knipe, D.M. and Howley, P.M. (eds.). Sixth edition. Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia, PA., pp. 1347–1401.

Falkinham, J.O. (2015). The Mycobacteriumavium complex and slowly growing mycobacteria. In: Molecular medical microbiology. Second edition. Elsevier Ltd., London, UK. pp. 1669–1678.

Falkinham, J.O. III, Hilborn, E.D., Arduino, M.J., Pruden, A., and Edwards, M.A. (2015). Epidemiology and ecology of opportunistic premise plumbing pathogens: Legionella pneumophila, Mycobacteriumavium, and Pseudomonas aeruginosa. Environ. Health Perspect., 123(8): 749–758.

Falkinham, J.O. III (2016a). Current epidemiologic trends of the nontuberculous mycobacteria (NTM). Curr. Environ. Health Rep., 3(2): 161–167.

Falkinham, J.O. (2016b). Nontuberculous mycobacteria: Community and nosocomial waterborne opportunistic pathogens. Clin. Microbiol. Newsl., 38(1): 1–7.

Farthing, M.J. (2000). Clinical aspects of human cryptosporidiosis. Contrib. Microbiol., 6:50–74.

Ferley, J.P., Zmirou, D., Balducci, F., Baleux, B., Fera, P., Larbaigt, G., Jacq, E., Moissonnier, B., Blineau, A., and Boudot, J. (1989). Epidemiological significance of microbiological pollution criteria for river recreational waters. Int. J. Epidemiol., 18: 198–205.

Fogarty, L.R., Haack, S.K., Johnson, H.E., Brennan, A.K., Isaacs, N.M., and Spencer, C. (2015). Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) at ambient freshwater beaches. J. Water Health, 13(3): 680–692.

Fricker, C.R. (2006). Campylobacter In: Waterborne pathogens. AWWA manual of water supply practices M48. Second edition. American Water Works Association, Denver CO. pp. 87–91.

FSA (2000). A report of the study of infectious intestinal disease in England. Food Standards Agency, HMSO, London, UK.

Gammie, L., Goatcher, L., and Fok, N. (2000). A Giardia/Cryptosporidium near miss? In: Proceedings of the 8th National Conference on Drinking Water, Quebec City, Quebec, October 28–30, 1998. Canadian Water and Wastewater Association, Ottawa, Ontario.

Geldreich, E.E. (revised by Degnan, A.J.) (2006). Pseudomonas In: Waterborne pathogens. AWWA manual of water supply practices M48. Second edition. American Water Works Association, Denver, CO. pp. 131–134.

George, K.L., Parker, B.C., Gruft, H., and Falkinham III, J.O. (1980). Epidemiology of infection by nontuberculous mycobacteria. II. Growth and survival in natural waters. Am. Rev. Respir. Dis., 122 (1): 89-94.

Gerba, C.P. (2000). Assessment of enteric pathogen shedding by swimmers during recreational activity and its impact on water quality. Quant. Microbiol., 2: 55–68.

Gofti-Laroche, L., Gratacap-Cavallier, B., Demanse, D., Genoulaz, O., Seigneurin, J.M., and Zmirou, D. (2003). Are waterborne astrovirus implicated in acute digestive morbidity (E.M.I.R.A. study)? J. Clin. Virol., 27(1): 74–82.

Goodwin, K.D., McNay, M., Cao, Y., Ebentier, D., Madison, M., and Griffith, J.F. (2012). A multi-beach study of Staphylococcus aureus, MRSA, and enterococci in seawater and beach sand. Water Res., 46: 4195–4207.

Gordy, M.A., Cobb, T.P., and Hanington, P.C. (2018). Swimmer’s itch in Canada: a look at the past and a survey of the present to plan for the future. Environ. Health, 17: 73.

Government of Canada (2020). National Enteric Surveillance Program Annual Summary 2019: Public Health Agency of Canada, Guelph, ON.

Government of Canada (2022a). Norovirus. Accessed June 2022 from:

Government of Canada (2022b). Symptoms of hepatitis E. Accessed June 2022 from:

Government of Canada (2022c). Fact Sheet – Community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA). Accessed June 2022 from:

Graciaa, D.S., Cope, J.R., Roberts, V.A., Cikesh, B.L., Kahler, A.M., Vigar, M., Hilborn, E.D., Wade, T.J., Backer, L.C., Montgomery, S.P., Secor, W.E., Hill, V.R., Beach, M.J., Fullerton, K.E., Yoder, J.S., and Hlavsa, M.C. (2018). Outbreaks associated with untreated recreational water – United States, 2000-2014. Morbidity and Mortality Weekly Report, 67(25): 701-706.

Graham, D.Y., Jiang, X., Tanaka, T., Opekun, A.R., Madore, H.P., and Estes, M.K (1994). Norwalk virus infection of volunteers: new insights based on improved assays. J. Infect. Disease, 170: 34–43.

Gray, J.J., Green, J., Cunliffe, C., Gallimore, C., Lee, J.V., Neal, K., and Brown, D.W.G. (1997). Mixed genogroup SRSV infections among a party of canoeists exposed to contaminated recreational water. J. Med. Virol., 52(4): 425–429.

Graziani, C., Losasso, C., Luzzi, I., Ricci, A., Scavia, G., and Pasquali, P. (2017). Salmonella. In: Foodborne diseases: Third edition. Dodd, C. et al. (eds.). Academic Press. Cambridge, MA. pp. 133–169.

Griffin, D.W., Gibson, C.J., Lipp, E.K., Riley, K., Paul, J.H. III, and Rose, J.B. (1999). Detection of viral pathogens by reverse transcriptase PCR and of microbial indicators by standard methods in the canals of the Florida Keys. Appl. Environ. Microbiol., 65: 4118–4125.

Griffith, J.F., Weisberg, S.B., Arnold, B.F., Cao, Y., Schiff, K.C., and Colford Jr., J.M. (2016). Epidemiologic evaluation of multiple alternate microbial water quality monitoring indicators at three California beaches. Water Res., 94: 371–381.

Guy, R.A., Payment, P., Krull, U.J., and Horgen, P.A. (2003). Real-time PCR for quantification of Giardia and Cryptosporidium in environmental water samples and sewage. Appl. Environ. Microbiol., 69(9): 5178–5185.

Guy, R.A., Arsenault, J., Kotchi, S.O., Gosselin-Théberge, M., Champagne, M.J., and Berthiaume, P. (2018). Campylobacter in recreational lake water in southern Quebec, Canada: presence, concentration, and association with precipitation and ruminant farm proximity. J. Water Health, 16(4): 516–529.

Haack, S.K., Fogarty, L.R., Stezer, E.A., Fuller, L.M., Brennan, A.K., Isaacs, N.M., and Johnson, H.E. (2013). Geographic setting influences Great Lakes beach microbiological water quality. Environ. Sci. Technol., 47: 12054–12063.

Haake, D.A. and Levett, P.N. (2015) Leptospirosis in Humans. In: Adler, B. (ed.) Leptospira and Leptospirosis. Current Topics in Microbiology and Immunology, vol 387. Springer, Berlin.

Haas, C.N., Rose, J.B., and Gerba, C.P. (2014). Quantitative microbial risk assessment. Second edition. John Wiley, New York, NY.

Hall, N.H. (2006). Legionella In: Waterborne pathogens. AWWA manual of water supply practices M48. Second edition:. American Water Works Association, Denver CO. pp. 119–124

Hallenbeck, W.H., and Brenniman, G.R. (1989). Risk of fatal amebic meningoencephalitis from waterborne Naegleria fowleri. Environ. Manag., 13(2): 227–232.

Hamilton, K.A., Weir, M.H., and Haas, C.N. (2017). Dose response models and a quantitative microbial risk assessment framework for the Mycobacteriumavium complex that account for recent developments in molecular biology, taxonomy, and epidemiology. Water Res., 109: 310–326.

Hanevik, K., Wensaas, K., Rortveit, G., Egil Eide, G., Mørch, and Langeland, N. (2014). Irritable bowel syndrome and chronic fatigue 6 years after Giardia infections: a controlled prospective cohort study. Clin. Infect. Dis., 59(10): 1394–1400.

Health Canada (2019a). Guidelines for Canadian Drinking Water Quality: Guideline Technical Document — Enteric Viruses. Water, Air and Climate Change Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, ON.

Health Canada (2019b). Guidelines for Canadian Drinking Water Quality: Guideline Technical Document — Enteric Protozoa: Giardia and Cryptosporidium. Water and Air Quality Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, ON.

Health Canada (2022a). Guidelines for Canadian Drinking Water Quality: Guidance on Waterborne Pathogens. Water and Air Quality Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, ON.

Health Canada (2022b). Guidelines for Canadian Recreational Water Quality: Guideline Technical Document - Cyanobacteria and their Toxins. Water and Air Quality Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, ON.

Health Canada (in publication-b). Guidelines for Canadian Recreational Water Quality: Guideline Technical Document – Fecal Indicator Organisms. Water and Air Quality Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, ON.

Health Canada (in publication-c). Guidelines for Canadian Recreational Water Quality: Summary of Recreational Water Quality Guidelines. Water and Air Quality Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, ON.

Health Canada (in publication-d). Guidelines for Canadian Recreational Water Quality: Guideline Technical Document – Understanding and Managing Risk in Recreational Waters. Water and Air Quality Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, ON.

Hellein, K.N., Battie, C., Tauchman, E., Lund, D., Oyarzabal, O.A., and Lepo, J.E. (2011) Culture-based indicators of fecal contamination and molecular microbial indicators rarely correlate with Campylobacter spp. in recreational waters. J. Water Health, 9: 695‒707.

Hewlett, E.L., Andrews, J.S., Jr., Ruffier, J., and Schaefer, and F.W. III (1982). Experimental infection of mongrel dogs with Giardia lamblia cysts and cultured trophozoites. J. Infect. Dis., 145(1): 89–93.

Hibler, C.P., Hancock, C.M., Perger, L.M., Wegrzyn, J.G., and Swabby, K.D. (1987). Inactivation of Giardia cysts with chlorine at 0.5 to 5.0°C. Technical Research Series, American Water Works Association, Denver, CO. 39 pp.

Hintaran, A.D., Kliffen, S.J., Lodder, W., Pijnacker, R., Brandwagt, D., van der Bij, A.K., Siedenburg, E., Sonder, G.J.B., Fanoy, E.B., and Joosten, R.E. (2018). Infection risk of city canal swimming events in the Netherlands in 2016. PLoS One, 13(7): e0200616.

Hlavsa, M.C., Cikesh, B.L., Roberts, V.A., Kahler, A.M., Vigar, M., Hilborn, E.D., Wade, T.J., Roellig, D.M., Murphy, J.L., Xiao, L., Yates, K.M., Kunz, J.M., Arduino, M.J., Reddy, S.C., Fullerton, K.E., Cooley, L.A., Beach, M.J., Hill, V.R., and Yoder, J.S. (2018). Outbreaks associated with treated recreational water — United States, 2000–2014. Am. J. Transplant., 18(7): 1815–1819.

Hoque, M.E., Hope, V.T., Scragg, R., and Kjellstrom, T. (2003). Children at risk of giardiasis in Auckland: a case–control analysis. Epidemiol. Infect., 131(1): 655–662.

Huang, H., Brooks, B.W., Lowman, R., and Carrillo, C.D. (2015). Campylobacter species in animal, food, and environmental sources, and relevant testing programs in Canada. Can. J. Microbiol., 61(10): 701–721.

Hunter, P.R. (1997). Waterborne disease—epidemiology and ecology. John Wiley and Sons, Chichester, UK.

Hunter, P.R. and Thompson, R.C. (2005). The zoonotic transmission of Giardia and Cryptosporidium. Int. J. Parasitol., 35(11–12): 1181–1190.

Hutson, A.M., Atmar, R.L., Marcus, D.M., and Estes, M.K. (2003). Norwalk virus-like particle hemagglutination by binding to H histoblood group antigens. J. Virol, 77: 405–415.

Isaac-Renton, J., Bowie, W.R., King, A., Irwin, G.S., Ong, C.S., Fung, C.P., Shokeir, M.O., and Dubey, J.P. (1998). Detection of Toxoplasma gondii oocysts in drinking water. Appl. Environ. Microbiol., 64(6): 2278–2280.

Ishii, S., Yan, T., Shively, D.A., Byappanahalli, M.N., Whitman, R.L., and Sadowsky, M.J. (2006). Cladophora (Chlorophyta) spp. harbor human bacterial pathogens in nearshore water of Lake Michigan. Appl. Environ. Microbiol., 72(7): 4545–4553.

Ishii, S. and Sadowsky, M.J. (2008). Escherichia coli in the environment: Implications for water quality and human health. Microbes Environ., 23(2): 101–108.

Janda, J.M. and Abbott, S.L. (2010). The genus Aeromonas: Taxonomy, pathogenicity, and infection. Clinical Microbiology Reviews, 23(1): 35–73.

Jiang, S.C. and Chu, W. (2004). PCR detection of pathogenic viruses in southern California urban rivers. J. Appl. Microbiol., 97: 17–28.

Jokinen, C.C., Koot, J., Cole, L., Desruisseau, A., Edge, T.A., Khan, I.U.H., Koning, W., Lapen, D.R., Pintar, K.D.M., Reid-Smith, R., Thomas, J.L., Topp, E., Wang, L.Y., Wilkes, G., Ziebell, K., van Bochove, E., and Gannon, V.P.J. (2015). The distribution of Salmonellaenterica serovars and subtypes in surface water from five agricultural regions across Canada. Water Res., 76: 120–131.

Jones, T.H., Brassard, J., Topp, E., Wilkes, G., and Lapen, D.R. (2017). Waterborne viruses and F-specific coliphages in mixed-use watersheds: microbial associations, host specificities, and affinities with environmental/land use factors. Appl. Environ. Microbiol., 83:e02763-16.

Juárez, M.M., Tártara, L.I., Cid, A.G., Real, J.P., Bermúdez, J.M., Rajal, V.B., and Palma, S.D. (2018). Acanthamoeba in the eye, can the parasite hide even more? Latest developments on the disease. Cont. Lens Anterior Eye, 41(3): 245–251.

Kadykalo, S., Thomas, J., Parmley, E.J., Pintar, K., and Fleury, M. (2020). Antimicrobial resistance of Salmonella and generic Escherichia coli isolated from surface water samples used for recreation and a source of drinking water is southwestern Ontario, Canada. Zoonoses Public Health, 67: 566–575.

Kaur, S. (2014). Chapter 9: Pathogenic mycobacteria and water. In: Water and health. Singh, P.P. and Sharma, V. (eds.) Springer. India. pp. 137–153.

Keithlin, J., Sargeant, J., Thomas, M.K., and Fazil, A. (2014). Chronic sequelae of E. coli O157: Systematic review and meta-analysis of the proportion of E. coli O157 cases that develop chronic sequelae. Foodborne Pathog. Dis., 11 (2): 79–95.

Keithlin, J., Sargeant, J.M., Thomas, M.K., and Fazil, A. (2015). Systematic review and meta-analysis of the proportion of non-typhoidal Salmonella cases that develop chronic sequelae. Epidemiol. Infect., 143: 1333–1351.

Khan, I.U.H., Loughborough, A., and Edge, T.A. (2009). DNA-based real-time detection and quantification of aeromonads from fresh water beaches on Lake Ontario. J. Water Health, 7(2): 312–323.

Khan, I.U.H., Hill, S., Nowak, E., Palmer, M.E., Jarjanzai, H., Lee, D.Y., Mueller, M., Schop, R., Weir, S., Irwin Abbey, A.M.I., Winter, J., and Edge, T.A. (2013a). Investigation of the prevalence of thermophilic Campylobacter species at Lake Simcoe recreational beaches. Inland Wat., 3: 93–104.

Khan, I.U.H., Hill, S., Nowak, E., and Edge, T.A. (2013b). Effect of incubation temperature on the detection of thermophilic Campylobacter species from freshwater beaches, nearby wastewater effluents, and bird fecal droppings. Appl. Environ. Microbiol., 79(24): 7639–7645.

Kobayashi, M., Oana, K., and Kawakami, Y. (2014). Bath water contamination with Legionella and nontuberculous mycobacteria in 24-hour home baths, hot springs, and public bathhouses in Nagano Perfecture, Japan. Jpn. J. Infect. Dis., 67: 276–281.

Kothary, M.H. and Babu, U.S. (2001). Infective dose of foodborne pathogens in volunteers: A review. J. Food Safety, 21(1): 49–73.

Kramer, M.H., Herwaldt, B.L., Craun, G.F., Calderon, R.L., and Juranek, D.D. (1996). Surveillance for waterborne-disease outbreaks—United States, 1993–1994. MMWR CDC Surveill. Summ., 45: 1–33.

Krikelis, V., Spyrou, N., Markoulatos, P., and Serie, C. (1985). Seasonal distribution of enteroviruses and adenoviruses in domestic sewage. Can. J. Microbiol., 31: 24–25.

Kucik, C.J., Martin, G.L., and Sortor, B.V. (2004). Common intestinal parasites. Am. Fam. Physician, 69(5):1161–1168.

La Rosa, G., Bonadonna, L., Lucentini, L., Kenmoe, S., and Suffredini, E. (2020). Coronavirus in water environments: occurrence, persistence and concentration methods – a scoping review. Water Res., 179: 115899.

Laitinen, O.H., Honkanen, H., Pakkanen, O., Oikarinen, S., Hankaniemi, M.M., Huhtala, H., Ruokoranta, T., Lecouturier, V., André, P., Harju, R., Virtanen, S.M., Lehtonen, J., Almond, J.W., Simell, T., Simell, O., Ilonen, J., Veijola, R., Knip, M., and Hyöty, H. (2014). Coxsackievirus B1 is associated with induction of ß-cell autoimmunity that portends type 1 diabetes. Diabetes, 63: 446–455.

Lan Chun, C., Kahn, C.I., Borchert, A.J., Byappanahalli, M.N., Whitman, R.L., Peller, J., Pier, C., Lin, G., Johnson, E.A., and Sadowsky, M.J. (2015). Prevalence of toxin-producing Clostridium botulinum associated with the macroalga Cladophora in three Great Lakes: growth and management. Sci. Total Environ., 511: 523–529.

Laverick, M.A., Wyn-Jones, A.P., and Carter, M.J. (2004). Quantitative RT-PCR for the enumeration of noroviruses (Norwalk-like viruses) in water and sewage. Lett. Appl. Microbiol., 39: 127–136.

LeChevallier, M.W., (2006). Mycobacterium avium complex. In: Waterborne pathogens. AWWA manual of water supply practices M48. Second edition. American Water Works Association, Denver CO. pp. 125–130.

Lee, S.H., Levy, D.A., Craun, G.F., Beach, M.J., and Calderon, R.L. (2002). Surveillance for waterborne-disease outbreaks—United States, 1999–2000. MMWR CDC Surveill. Summ., 51: 1–47.

Lee, C.S., Lee, C., Marion, J., Want, Q., Saif, L., and Lee, J. (2014). Occurrence of human enteric viruses at freshwater beaches during swimming season and its link to water inflow. Sci. Total Environ., 472: 757–766.

Leighton, B.J., Ratzlaff, D., McDougall, C., Stewart, G., Nadine, A., and Gustafson, L. (2004). Schistosome dermatitis at Crescent Beach—preliminary report. Environ. Health Rev., Spring: 5–13.

Lennon, G., Cashman, O., Lane, K., Cryan, B., and O'Shea, H. (2007). Prevalence and characterization of enteric adenoviruses in the south of Ireland. J. Med. Virol., 79(10): 1518–1526.

Leoni, E., Catalani, F., Marini, S., and Dallolio, L. (2018). Legionellosis associated with recreational waters: a systematic review of cases and outbreaks in swimming pools, spa pools, and similar environments. Int. J. Environ. Res. Public Health, 15: 1612.

Levantesi, C., Bonadonna, L., Briancesco, R., Grohmann, E., Toze, S., and Tandoi, V. (2012). Salmonella in surface and drinking water: occurrence and water-mediated transmission. Food Res. Int., 45: 587–602.

Lévesque, B., Giovenazzo, P., Guerrier, P., Laverdière, D., and Prud’Homme, H. (2002). Investigation of an outbreak of cercarial dermatitis. Epidemiol. Infect., 129: 379–386.

Levett P.N. (2015) Systematics of Leptospiraceae. In: Leptospira and Leptospirosis. Current Topics in Microbiology and Immunology, vol 387. Adler, B. (ed.). Springer, Berlin.

Levin-Edens, E., Soge, O.O., No, D., Stiffarm, A., Meschke, J.S., and Roberts, M.C. (2012). Methicillin-resistant Staphylococcus aureus from Northwest marine and freshwater recreational beaches. FEMS Microbiol. Ecol., 79: 412–420.

Levy, D.A., Bens, M.S., Craun, G.F., Calderon, R.L, and Herwaldt, B.L. (1998). Surveillance for waterborne-disease outbreaks—United States, 1995–1996. MMWR CDC Surveill. Summ., 47: 1–34.

Lightfoot, D. (2004). Salmonella and other enteric organisms. In: Waterborne zoonoses: identification, causes, and control. Cotruvo, J.A., Dufour A., Rees, G., Bartram, J., Carr, R., Cliver, D.O., Craun, G.F., Fayer, R., and Gannon, V.P.J. (eds.). IWA Publishing, London, UK pp. 228–241.

Lindesmith, L., Moe, C., Marionneau, S., Ruvoën, N., Jiang, X., Lindblad, L., Stewart, P., Lependu, J., and Baric, R. (2003). Human susceptibility and resistance to Norwalk virus infection. Nat. Med., 9(5): 548–553.

Lipp, E.K., Kurz, R., Vincent, R., Rodriguez-Palacios, C., Farrah, S.R., and Rose, J.B. (2001). The effects of seasonal variability and weather on microbial fecal pollution and enteric pathogens in a subtropical estuary. Estuaries, 24: 266–276.

Lönnrot, M., Korpela, K., Knip, M., Ilonen, J., Simell, O., Korhonen, S., Savola, K., Muona, P., Simell, T., Koskela, P., and Hyöty, H. (2000). Enterovirus infections as a risk factor for ß-cell autoimmunity in a prospectively observed birth cohort: The Finnish diabetes prediction and prevention study. Diabetes, 49(8): 1314–1318.

LPSN (2019). List of prokaryote names with standing in nomenclature (LPSN). Retrieved June 2019, from

LPSN (2020) Genus Pseudomonas. Retrieved October 2020, from

Manitoba Water Stewardship (2007). Manitoba’s water protection handbook. Manitoba Water Stewardship, Winnipeg, MB. Available at:

Marciano-Cabral, F., and Cabral, G.A. (2007). The immune response to Naegleria fowleri amebae and pathogenesis of infection. FEMS Immunol. Med. Microbiol., 51(2): 243–259.

Marino, F., Moringo, M., Martinez-Manzanares, E., and Borrego, J. (1995). Microbiological-epidemiological study of selected marine beaches in Malaga (Spain). Water Sci. Technol., 31: 5–9.

Marion, J.W., Lee, C., Lee, C.S., Wang, Q., Lemeshow, S., Buckley, T.J., Saif, L.J., and Lee, J. (2014). Integrating bacterial and viral water quality assessment to predict swimming-associated illness at a freshwater beach: A cohort study. PLoS One, 9(11).

Marthaler, D., Rossow, K., Gramer, M., Collins, J., Goyal, S., Tsunemitsu, H., Kuga, K., Suzuki, T., Ciarlet, M., and Matthijnssens, J. (2012). Detection of substantial porcine group B rotavirus genetic diversity in the United States, resulting in a modified classification proposal for G genotypes. Virology, 433(1): 85–96.

Matson, D.O. (2004). Caliciviruses and hepatitis E virus. In: Textbook of pediatric infectious diseases. Feigin, R.D., Cherry, J.D., Demmler, G.J., and Kaplan, S.L. (eds.). Fifth edition. Saunders Co., Philadelphia, PA.

McBride, G.B., Stott, R., Miller, W., Bambic, D., and Wuertz, S. (2013). Discharge-based QMRA for estimation of public health risks from exposure to stormwater-borne pathogens in recreational waters in the United States. Water Res., 47: 5282–5297.

Medema G.J., Shaw S., Waite M., Snozzi M., Morreau A., and Grabow W. (2003). Chapter 4: Catchment characterisation and source water quality. In: Assessing microbial safety of drinking water. World Health Organization, Geneva, Switzerland, pp. 111–158.

Medema, G.J., Teunis, P.F.M., Havelaar, A.H., and Haas, C.N. (1996). Assessment of the dose-response relationship of Campylobacter jejuni. Int. J. Food Microbiol., 30 (1-2):101–111.

Mena, K.D., and Gerba, C.P. (2009). Waterborne adenovirus. Rev. Environ. Contam. Toxicol., 198: 133–167.

Méndez, E., and Arias, C.F. (2007). Astroviruses. In: Fields Virology. Knipe, D.M. and Howley, P.M. (eds.). Fifth edition. Lippincott Williams & Wilkins, Philadelphia, PA.

Mercado, R., Buck, G.A., Manque, P.A., and Ozaki, L.S. (2007). Cryptosporidium hominis infection of the human respiratory tract. Emerg. Infect. Dis., 13(3): 462–464.

Messner, M.J., Chappell, C.L., and Okhuysen, P.C. (2001). Risk assessment for Cryptosporidium: a hierarchical Bayesian analysis of human dose response data. Water Res., 35: 3934–3940.

Moore, A.C., Herwaldt, B.L., Craun, G.F., Calderon, R.L., Highsmith, A.K., and Juranek, D.D. (1993). Surveillance for waterborne disease outbreaks—United States, 1991–1992. MMWR CDC Surveill. Summ., 42: 1–22.

Moore, J.E., Gilpin, D., Crothers, E., Canney, A., Kaneko, A., and Matsuda, M. (2002). Occurrence of Campylobacter spp. and Cryptosporidium spp. in seagulls (Larus spp.). Vector Borne Zoonotic Dis., 2: 111–114.

Moore, E.R.B., Tindall, B.J., Martins Dos Santos, V.A.P., Pieper, D.H., Ramos, J-L., and Palleroni, N.J. (2006). Nonmedical: Pseudomonas. In: The Prokaryotes: A handbook on the biology of bacteria. Third edition. Volume 4: Bacteria: Firmicutes, Cyanobacteria. Dworkin, M., et al. (eds.). Springer, Singapore. pp. 646–703.

Morgan, D.R., Johnson, P.C., DuPont, H.L., Satterwhite, T.K., and Wood, L.V. (1985). Lack of correlation between known virulence properties of Aeromonas hydrophila and enteropathogenicity for humans. Infect. Immun., 50(1): 62–65.

Moyer, N.P. (revised by Standridge, J.) (2006). Aeromonas In: Waterborne pathogens. AWWA manual of water supply practices M48. Second edition:. American Water Works Association, Denver, CO. pp. 81–85.

Nairn, C., Galbraith, D.N., Taylor, K.W., and Clements, G.B. (1999). Enterovirus variants in the serum of children at the onset of type 1 diabetes mellitus. Diabetic Med., 16(6): 509–513.

NASEM (2020). Management of Legionella in Water Systems. National Academies of Sciences, Engineering, and Medicine, Washington, DC: The National Academies Press.

Oikarinen, S., Tauriainen, S., Hober, D., Lucas, B., Vazeou, A., Sioofy-Khojine, A., Bozas, E., Muir, P., Honkanen, H., Ilonen, J., Knip, M., Keskinen, P., Saha, M., Huhtala, H., Stanway, G., Bartsocas, C., Ludvigsson, J., Taylor, K., and Hyöty, H. (2014). Virus antibody survey in different European populations indicates risk association between coxsackievirus B1 and type 1 diabetes. Diabetes, 63(2): 655–662.

Oishi, I., Yamazaki, K., Kimoto, T., Minekawa, Y., Utagawa, E., Yamazaki, S., Inouye, S., Grohmann, G.S., Monroe, S.S., Stine, S.E., Carcamo, C., Ando, T., and Glass, R.I. (1994). A large outbreak of acute gastroenteritis associated with astrovirus among students and teachers in Osaka. Japan. J. Infect. Dis., 170(2): 439–443.

Okhuysen, P.C., Chappell, C.L., Serling, C.R., Jakubowski, W., and DuPont, H.L. (1998). Susceptibility and serologic response of healthy adults to reinfection with Cryptosporidium parvum. Infect. Immunol., 66:441–443.

Okhuysen, P.C., Chappell, C.L., Crabb, J.H., Sterling, C.R., and DuPont, H.L. (1999). Virulence of three distinct Cryptosporidium parvum isolates for healthy adults. J. Infect. Dis., 180:1275–1281.

Okhuysen, P.C., Rich, S.M., Chappell, C.L., Grimes, K.A., Widmer, G., Feng, X., and Tzipori, S. (2002). Infectivity of a Cryptosporidium parvum isolate of cervine origin for healthy adults and interferon-gamma knockout mice. J. Infect. Dis., 185(9): 1320–1325.

Olson, M.E., Thorlakson, C.L., Deselliers, L., Worck, D.W., and McAllister, T.A. (1997). Giardia and Cryptosporidium in Canadian farm animals. Vet. Parasitol., 68: 375–381.

Ortega, Y.R., and Sanchez, R. (2010). Update on Cyclospora cayetanensis, a food-borne and waterborne parasite. Clinical Microbiology Reviews, 23(1): 218–234.

Oster, R.J., Wijesinghe, R.U., Haack, S.K., Fogarty, L.R., Tucker, T.R., and Riley, S.C. (2014). Bacterial pathogen gene abundance and relation to recreational water quality at seven Great Lakes beaches. Environ. Sci. Technol., 48: 14148‒14157.

Pallansch, M., and Roos, R. (2007). Enteroviruses: Polioviruses, coxsackieviruses, echoviruses, and newer enteroviruses. In: Fields Virology. Knipe, D.M. and Howley, P.M. (eds.). Fifth edition. Lippincott Williams & Wilkins, Philadelphia, PA.

Palombo, E.A. and Bishop, R.F. (1996). Annual incidence, serotype distribution, and genetic diversity of human astrovirus isolates from hospitalized children in Melbourne, Australia. J. Clin. Microbiol., 34(7): 1750–1753.

Pang, X., Qiu, Y., Gao, T., Zurawell, R., Neumann, N.F., Craik, S., and Lee, B.E. (2019). Prevalence, levels and seasonal variations of human enteric viruses in six major rivers in Alberta, Canada. Water Res., 153: 349–356.

Payment, P. (1984). Viruses and bathing beach quality. Can. J. Public Health, 75: 43–48.

Payment, P., Berte, A., Prevost, M., Menard, B., and Barbeau, B. (2000). Occurrence of pathogenic microorganisms in the Saint Lawrence River (Canada) and comparison of health risks for populations using it as their source of drinking water. Can. J. Microbiol., 46: 565–576.

Percival, S.L., Chalmers, R.L., Embrey, M., Hunter, P.R., Sellwood, J., and Wyn-Jones, P. (2004). Microbiology of waterborne diseases. Elsevier Academic Press, San Diego, CA.

Percival, S.L., and Williams, D.W. (2014a). Aeromonas. In: Microbiology of waterborne diseases: Microbiological aspects and risks: Second edition. Elsevier Ltd., Oxford, UK. pp. 49–64.

Percival, S.L., and Williams, D.W. (2014b). Campylobacter. In: Microbiology of waterborne diseases: Microbiological aspects and risks: Second edition. Elsevier Ltd., Oxford, UK. pp. 65–78.

Percival, S.L., and Williams, D.W. (2014c). Escherichia coli. In: Microbiology of waterborne diseases: Microbiological aspects and risks: Second edition. Elsevier Ltd., Oxford, UK. pp. 89–117.

Percival, S.L., and Williams, D.W. (2014d). Legionella. In: Microbiology of waterborne diseases: Microbiological aspects and risks: Second edition. Elsevier Ltd., Oxford, UK. pp. 155–175.

Percival, S.L., and Williams, D.W. (2014e). Mycobacterium. In: Microbiology of waterborne diseases. Second edition. Elsevier Ltd., Oxford, UK, pp. 177–207.

Percival, S.L., and Williams, D.W. (2014f). Salmonella. In: Microbiology of waterborne diseases: Microbiological aspects and risks. Second edition. Elsevier Ltd., Oxford, UK. pp. 209–222.

Percival, S.L., and Williams, D.W. (2014g). Shigella. In: Microbiology of waterborne diseases: Microbiological aspects and risks. Second edition. Elsevier Ltd., Oxford, UK. pp. 223–236.

PHAC (2004). Notifiable diseases online: leptospirosis. Available at:

PHAC (2010). Pathogen Safety Data Sheets: Infectious Substances – Shigella spp. Public Health Agency of Canada, Ottawa, ON. [accessed September 2019].

PHAC (2018). Canadian antimicrobial resistance surveillance system. Update 2018. Public Health Agency of Canada. Ottawa, ON. [accessed October 2019].

PHAC. (2022). Notifiable diseases on-line. Reported cases from 1924 to 2019 in Canada. Public Health Agency of Canada, Ottawa, Canada. Accessed June 2022 from:

Pina, S., Puig, M., Lucena, F., Jofre, J., and Girones, R. (1998). Viral pollution in the environment and in shellfish: human adenovirus detection by PCR as an index of human viruses. Appl. Environ. Microbiol., 64: 3376–3382.

Pintar, K., Thomas, K.M., Christidis, T., Otten, A., Nesbitt, A., Marshall, B., Pollari, F., Hurst, M., and Ravel, A. (2017) A comparative exposure assessment of Campylobacter in Ontario, Canada. Risk Anal., 37: 677–715.

Plano, L.R.W., Garza, A.C., Shibata, T., Elmir, S.M., Kish, J., Sinigalliano, C.D., Gidley, M.L., Miller, G., Withum, K., Fleming, L.E., and Solo-Gabriele, H.M. (2011). Shedding of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus from adult and pediatric bathers in marine waters. BMC Microbiol., 11:5.

Plano, L.R.W., Shibata, T., Garza, A.C., Kish, J., Fleisher, J.M., Sinigalliano, C.D., Gidley, M.L., Withum, K., Elmir, S.M., Hower, S., Jackson, C.R., Barrett, J.B., Cleary, T., Davidson, M., Davis, J., Mukherjee, S., Fleming, L.E., and Solo-Gabriele, H.M. (2013). Human-associated methicillin-resistant Staphylococcus aureus from a subtropical recreational marine beach. Microb. Ecol., 65: 1039–1051.

Plutzer, J., Törökné, A., and Karanis, P. (2010). Combination of ARAD microfiber filtration and LAMP methodology for simple, rapid and cost-effective detection of human pathogenic Giardi duodenalis and Cryptosporidium spp. in drinking water. Lett. Appl. Microbiol., 50: 82–88.

Pond, K. (2005). Water recreation and disease. Plausibility of associated infections: acute effects, sequelae and mortality. IWA Publishing, London, UK.

Pond, K., Rueedi, J., and Pedley, S. (2004). Pathogens in drinking water sources (MicroRisk literature review). Available at:

Prystajecky, M., Tsui, C.K.M., Hsiao, W.L., Uyaguari-Diaz, M.I., Ho, J., Tang, P., and Isaac-Renton, J. (2015). Giardia spp. are commonly found in mixed assemblages in surface water, as revealed by molecular and whole-genome characterization. Appl. Environ. Microbiol., 81: 4827–4834.

Priyadarshi, N. (2005). Cultural eutrophication. In: Water encyclopedia, Vol. 3, Surface and agricultural water. Lehr, J.H. and Keeley, J. (eds.). John Wiley and Sons, Hoboken, NJ.

Puig, M., Jofre, J., Lucena, F., Allard, A., Wadell, G., and Girones, R. (1994). Detection of adenoviruses and enteroviruses in polluted waters by nested PCR amplification. Appl. Environ. Microbiol., 60: 2963–2970.

Ravel, A., Hurst, M., Petrica, N., David, J., Mutschall, S.K., Pintar, K., Taboada, E.N., and Pollari, F. (2017). Source attribution of human campylobacteriosis at the point of exposure by combining comparative exposure assessment and subtype comparison based on comparative genomic fingerprinting. PLoS ONE, 12(8): e0183790.

Rendtorff, R.C. (1978). The experimental transmission of Giardia lamblia among volunteer subjects. In: Waterborne transmission of giardiasis. Jakubowski, W. and Hoff, J.C. (eds.). United States Environmental Protection Agency, Cincinnati, OH. pp. 64–81 (EPA 600/9-79-001).

Roach, P.D., Olson, M.E., Whitley, G., and Wallis, P.M. (1993). Waterborne Giardia cysts and Cryptosporidium oocysts in the Yukon, Canada. Appl. Environ. Microbiol., 59(1): 67–73.

Robins-Browne, R.M., Holt, K.E., Ingle, D.J., Hocking, D.M., Yang, J., and Tauschek, M. (2016). Are Escherichia coli pathotypes still relevant in the era of whole-genome sequencing? Front. Cell. Infect. Microbiol., 6 (NOV), art. no. 141.

Roivainen, M., Alfthan, G., Jousilahti, P., Kimpimäki, M., Hovi, T., and Tuomilehto, J. (1998). Enterovirus infections as a possible risk factor for myocardial infarction. Circulation, 98:23): 2534–2537.

Rose, J.B., Mullinax, R.L., Singh, S.N., Yates, M.V., and Gerba, C.P. (1987) Occurrence of rotaviruses and enteroviruses in recreational waters of Oak Creek, Arizona. Water Res., 11,


Rose, J.B., Epstein, P.R., Lipp, E.K., Sherman, B.H., Bernard, S.M., and Patz, J.A. (2001). Climate variability and change in the United States: potential impacts on water- and foodborne diseases caused by microbiologic agents. Environ. Health Perspect. 109 (Suppl. 2): 211-221

Rotbart, H.A. (1995). Human enterovirus infections. ASM Press, Washington, DC.

Rudko, S.P., Reimink, R.L., Froelich, K., Gordy, M.A., Blankespoor, C.L., and Hanington, P.C. (2018). Use of qPCR-based cercariometry to assess swimmer’s itch in recreational lakes. EcoHealth, 15: 827–839.

Ryan, U.M., Bath, C., Robertson, I., Read, C., Elliot, A., McInnes, L., Traub, R., and Besier, B. (2005). Sheep may not be an important zoonotic reservoir for Cryptosporidium and Giardia parasites. Appl. Environ. Microbiol., 71(9): 4992–4997.

Ryan, U., Fayer, R., and Xiao, L. (2014). Cryptosporidium species in humans and animals: current understanding and research needs. Parasitology. 141:1667–1685.

Sanchez-Vargas, F.M., Abu-El-Haija, M.A., and Gomez-Duarte, O.G. (2011). Salmonella infections: An update on epidemiology, management, and prevention. Travel Med. Infect. Dis., 9(6): 263–277.

Sassoubre, L.M., Love, D.C., Silverman, A.I., Nelson, K.L., and Boehm, A.B. (2012). Comparison of enterovirus and adenovirus concentration and enumeration methods in seawater from Southern California, USA and Baja Malibu, Mexico. J. Water Health, 10 (3): 419–430.

Schets, F.M., van den Berg, H.H.J.L., Vennema, H., Pelgrim, M.T.M., Collé, C., Rutjes, S.A., and Lodder, W.J. (2018). Norovirus outbreak associated with swimming in a recreational lake not influenced by external human fecal sources in The Netherlands, August 2012. Int. J. Environ. Res. Public Health, 15: 2550.

Schoen, M.E. and Ashbolt, N.J. (2010). Assessing pathogen risk to swimmers at non-sewage impacted recreational beaches. Environ. Sci. Technol., 44: 2286–2291.

Schönberg-Norio, D., Takkinen, J., Hänninen, M.L., Katila, M.L., Kaukoranta, S.S., Mattila, L., and Rautelin, H. (2004). Swimming and Campylobacter infections. Emerg. Infect. Dis., 10(8):1474–1477.

Schulze-Robbecke, R. and Buchholtz, K. (1992). Heat susceptibility of aquatic mycobacteria. Appl. Environ. Microbiol., 58(6): 1869–1873.

Schuster, F.L. and Visvesvara, G.S. (2004). Amebae and ciliated protozoa as causal agents of waterborne zoonotic disease. Vet. Parasitol. 126:91–120.

Schvoerer, E., Ventura, M., Dubos, O., Cazaux, G., Serceau, R., Gournier, N., Dubois, V., Caminade, P., Fleury, H.J., and Lafon, M.E. (2001). Qualitative and quantitative molecular detection of enteroviruses in water from bathing areas and from a sewage treatment plant. Res. Microbiol., 152(2): 179–186.

Sckrabulis, J.P., Flory, A.R., and Raffel, T.R. (2020). Direct onshore wind predicts daily swimmer’s itch (avian schistosome) incidence at a Michigan beach. Parasitology, 147: 431–440.

Seyfried, P.L. and Cook, R.J. (1984). Otitis externa infections related to Pseudomonas aeruginosa levels in five Ontario lakes. Can. J. Public Health, 75: 83–91.

Seyfried, P.L., Tobin, R.S., Brown, N.E., and Ness, P.F. (1985). A prospective study of swimming-related illness, II. Morbidity and the microbiological quality of water. AJPH, 75(9): 1071–1075.

Shah, C., Baral, R., Bartaula, B., and Shrestha, L.B. (2019). Virulence factors of uropathogenic Escherichia coli (UPEC) and correlation with antimicrobial resistance. BMC Microbiol., 19: 204.

Shapiro, K., Bahia-Oliveira, L., Dixon, B., Dumètre, A., de Wit, L.A., VanWormer, E., and Villena, I. (2019). Environmental transmission of Toxoplasma gondii: Oocysts in water, soil and food. Food Waterborne Parasitol., 12: e00049.

Siddiqui, R., Ali, I.K.M., Cope, J.R., and Khan, N.A. (2016). Biology and pathogenesis of Naegleria fowleri. Acta Trop., 164: 375–394.

Simmonds, P., Gorbalenya, A.E., Harvala, H., Hovi, T., Knowles, N.J., Lindberg, A.M., Oberste, M.S., Palmenberg, A.C., Reuter, G., Skern, T., Tapparel, C., Wolthers, K.C., Woo, P.C.Y., and Zell, R. (2020). Recommendations for the nomenclature of enteroviruses and rhinoviruses. Arch. Virol., 165: 793–797.

Sinclair, R.G., Jones, E.L., and Gerba, C.P. (2009). Viruses in recreational water-borne disease outbreaks: A review. J. Appl. Microbiol., 107(6): 1769–1780.

Smith, D.B., Simmonds, P., Jameel, S., Emerson, S.U., Harrison, T.J., Meng, X., Okamoto, H., Van der Poel, W.H.M., and Purdy, M.A. (2014). Consensus proposals for classification of the family hepeviridae. J. Gen. Virol., 95: 2223–2232.

Soller, J.A., Bartrand, T., Ashbolt, N.J., Ravenscroft, J., and Wade T.J. (2010). Estimating the primary etiologic agents in recreational freshwaters impacted by human sources of fecal contamination. Water Res., 44: 4736–4747.

Springer, G.L. and Shapiro, E.D. (1985). Fresh water swimming as a risk factor for otitis externa: a case–control study. Arch. Environ. Health, 40: 202–206.

Steele, J.A., Blackwood, A.D., Griffith, J.F., Noble, R.T., and Schiff, K.C. (2018). Quantification of pathogens and markers of fecal contamination during storm events along popular surfing beaches in San Diego, California. Water Research, 136: 137–149.

Stinear, T., Ford, T., and Vincent, V. (2004). Analytical methods for the detection of waterborne and environmental pathogenic mycobacteria. In: Pathogenic mycobacteria in water. A guide to public health consequences, monitoring and management. Pedley, S. (ed.). IWA Publishing. World Health Organization., Geneva, Switzerland. pp. 55–73.

Stout, J.E., Koh, W.J., and Yew, W.W. (2016). Update on pulmonary disease due to non-tuberculous mycobacteria. Int. J. Infect. Dis., 45: 123–134.

Stuart, J.M., Orr, H.J., Warburton, F.G., Jeyakanth, S., Pugh, C., Morris, I., Sarangi, J., and Nichols, G. (2003). Risk factors for sporadic giardiasis: a case–control study in southwestern England. Emerg. Infect. Dis., 9(2):229–233.

Surman-Lee, S., Fields, B., Hornei, B., Ewig, S., Exner, M., Tartakovsky, I., Lajoie, L., Dangendorf, F., Bentham, R., Cabanes, P.A., Fourrier, P., Trouvet, T., and France Wallet, F. (2007). Chapter 2: Ecology and environmental sources of Legionella. In: Legionella and the prevention of legionellosis. Bartram, J. (eds.). World Health Organization, Geneva, Switzerland. pp. 29–38.

Tani, N., Dohi, Y., Kurumatani, N., and Yonemasu, K. (1995). Seasonal distribution of adenoviruses, enteroviruses and reoviruses in urban river water. Microbiol. Immunol., 39: 577–580.

Taylor, L.H., Latham, S.M., and Woolhouse, M.E.J. (2001). Risk factors for human disease emergence. Philos. Trans. R. Soc. B Biol. Sci., 356(1411): 983–989.

Teunis, P.F.M., Bonačić Marinović, A., Tribble, D.R., Porter, C.K., and Swart, A. (2018). Acute illness from Campylobacter jejuni may require high doses while infection occurs at low doses. Epidemics, 24:1–20.

Teunis, P.F.M., van den Brandhof, W., Nauta, M., Wagenaar, J., van den Kerkhof, H., and van Pelt, W. (2005). A reconsideration of the Campylobacter dose–response relation. Epidemiol. Infect., 133 (4): 583-592.

Thomas, J.M. and Ashbolt, N.J. (2011). Do free-living amoebae in treated drinking water systems present an emerging health risk? Environ. Sci. Technol., 45(3): 860–869.

Thompson, R.C. (2004). The zoonotic significance and molecular epidemiology of Giardia and giardiasis. Vet. Parasitol., 126(1–2):15–35.

Traub, R.J., Monis, P.T., Robertson, I., Irwin, P., Mencke, N., and Thompson, R.C. (2004). Epidemiological and molecular evidence supports the zoonotic transmission of Giardia among humans and dogs living in the same community. Parasitology, 128(Pt. 3):253–262.

Traub, R.J., Robertson, I.D., Irwin, P.J., Mencke, N., and Thompson, R.C. (2005). Canine gastrointestinal parasitic zoonoses in India. Trends Parasitol., 21(1):42–48.

US EPA (2006). Aeromonas: Human health criteria document. Office of Science and Technology. United States Environmental Protection Agency, Washington, DC. (EPA/68-C-02-026).

van Asperen, I.A., de Rover, C.M., Schijven, J.F., Oetomo, S.B., Schellekens, J.F., van Leeuwen, N.J., Colle, C., Havelaar, A.H., Kromhout, D., and Sprenger, M.W. (1995). Risk of otitis externa after swimming in recreational fresh water lakes containing Pseudomonas aeruginosa. Br. Med. J., 311: 1407–1410.

van der Poel, W. and Rzezutka, A. (2017). Hepatitis A. In: Global Water

Pathogen Project. Rose, J.B. and Jiménez-Cisneros, B. (eds). (J.S Meschke, and R. Girones (eds) Part 3 Viruses).

Verbrugge, L.M., Rainey, J., Reimink, R., and Blankespoor, H. (2004). Prospective study of swimmer’s itch incidence and severity. J. Parasitol., 90(4): 697–704.

Vergara, G.G.R.V, Rose, J.B., and Gin, K.Y.H. (2016). Risk assessment of noroviruses and human adenoviruses in recreational surface waters. Water Research, 103: 276–282.

Verhoef, L., Hewitt, J., Barclay, L., Ahmed, S.M., Lake, R., Hall, A.J., Lopman, B., Kroneman, A., Vennema, H., Vinje, J., and Koopmans, M. (2015). Norovirus genotype profiles associated with foodborne transmission, 1999-2012. Emerg. Infect. Dis., 21(4): 592–599.

Verhougstraete, M.P., Byappanahalli, M.N., Rose, J.B., and Whitman, R.L. (2010). Cladophora in the Great Lakes: impacts on beach water quality and human health. Water Sci. Technol., 62(1): 68–76.

Visvesvara, G.S. and Moura, H. (2006). Naegleria fowleri. In: Waterborne pathogens. AWWA manual of water supply practices M48. American Water Works Association, Denver, CO. pp. 229–232.

Visvesvara, G.S., Moura, H., and Schuster, F.L. (2007). Pathogenic and opportunistic free-living amoebae: Acanthamoeba spp., Balamuthia mandrillaris, Naegleria fowleri, and Sappinia diploidea. FEMS Immunol. Med. Microbiol., 50(1): 1–26.

Wade, T.J., Augustine, S.A.J., Griffin, S.M., Sams, E.A., Oshima, K.H., Egorov, A.I., Simmons, K.J., Eason, T.N., and Dufour, A. (2018). Asymptomatic norovirus infection associated with swimming at a tropical beach: a prospective cohort study. PLoS ONE, 13(3): e0195056.

Wagenaar, J.A., Newell, D.G., Kalupahana, R.S., and Lapo Mughini-Gras, L. (2015). Campylobacter: Animal reservoirs, human infections, and options for control. In: Zoonoses –Infections affecting humans and animals: Focus on public health aspects. Sing, A. (ed.). Springer. Dordrecht, Netherlands. pp. 159–177.

Watson, S.B., Zastepa, A., Boyer, G.L., and Matthews, E. (2017) Algal bloom response and risk management: On-site response tools. Toxicon, 129: 144–152.

Wensaas, K.A., Langeland, N., Hanevik, K., Mørch, K., Eide, G.E., and Rortveit, G. (2012). Irritable bowel syndrome and chronic fatigue 3 years after acute giardiasis: historic cohort study. Gut., 61:214–219.

Whitman, R.L., Shively, D.A., Pawlik, H., Nevers, M.B., and Byappanahalli, M.N. (2003). Occurrence of Escherichia coli and enterococci in Cladophora (Chlorophyta) in nearshore water and beach sand of Lake Michigan. Appl. Environ. Microbiol., 69: 4714–4719.

WHO (2003). Guidelines for safe recreational water environments. Vol. 1. Coastal and fresh waters. World Health Organization, Geneva, Switzerland. Available at:

WHO (2006). Guidelines for safe recreational water environments. Vol. 2. Swimming pools and similar environments. World Health Organization, Geneva, Switzerland. Available at:

WHO (2017). Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug-resistant bacterial infections, including tuberculosis. World Health Organization. Geneva, Switzerland. [accessed October 2019]. Wong, K., Fong, T, Bibby, K., and Molina, M. (2012). Application of enteric viruses for fecal pollution source tracking in environmental waters. Environ. International, 45: 151-164. Wynwood, S.J., Graham, G.C., Weier, S.L., Collet, T.A., McKay, D.B., and Craig, S.B. (2014). Leptospirosis from water sources. Pathog. Glob. Health, 108(7): 334–338.

Xagoraraki, I., Kuo, D.H., Wong, K., Wong, M., and Rose, J.B. (2007). Occurrence of human adenoviruses at two recreational beaches of the Great Lakes. Appl. Environ. Microbiol., 73(24): 7874–7881.

Yayli, G., Kiliç, S., and Örmeci, A.R. (2002). Hepatitis agents with enteric transmission--an epidemiological analysis. Infection, 30(6): 334–337.

 Yoder, J.S., Blackburn, B.G., Craun, G.F., Hill, V., Levy, D.A., Chen, N., Lee, S.H., Calderon, R.L., and Beach, M.J. (2004). Surveillance for waterborne-disease outbreaks associated with recreational water—United States, 2001–2002. MMWR CDC Surveill. Summ., 53: 1–22.

Yoder, J.S., Eddy, B.A., Visvesvara, G.S., Capewell, L., and Beach, M.J. (2010). The epidemiology of primary amoebic meningoencephalitis in the USA, 1962-2008. Epidemiol. Infect., 138(7): 968–975.

Yoder, J.S., Straif-Bourgeois, S., Roy, S.L., Moore, T.A., Visvesvara, G.S., Ratard, R.C., Hill, V.R., Wilson, J.D., Linscott, A.J., Crager, R., Kozak, N.A., Sriram, R., Narayanan, J., Mull, B., Kahler, A.M., Schneeberger, C., Da Silva, A.J., Poudel, M., Baumgarten, K.L., Xiao, L., and Beach, M.J. (2012). Primary amebic meningoencephalitis deaths associated with sinus irrigation using contaminated tap water. Clin. Infect. Dis., 55(9): e7-e85.

Zahedi, A., Paparini, A., Jian, F., Robertson, I., and Ryan, U. (2016). Public health significance of zoonotic Cryptosporidium species in wildlife: Critical insights into better drinking water management. Int. J. Parasitol.: Parasites Wildl. 5: 88–109.

Zaongo, S.D., Shaio, M.F., and Ji, D.D. (2018). Effects of culture media on Naegleria fowleri growth at different temperatures. J. Parasitol., 104 (5):451–456.

Appendix: List of abbreviations

acquired immunodeficiency syndrome
Acanthamoeba keratitis
Centers for Disease Control and Prevention
deoxyribonucleic acid
E. coli
Escherichia coli
enterohemorrhagic Escherichia coli
enteroinvasive Escherichia coli
hepatitis A virus
hepatitis E virus
hemolytic uremic syndrome
methicillin-resistant Staphylococcus aureus
non-tuberculous mycobacteria
primary amoebic meningoencephalitis
polymerase chain reaction
ribonucleic acid
uropathogenic E. coli

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