Biomonitoring Content Summary for the Canadian Health Measures Survey: Cycles 1-4 (2007-2015)

These chemicals have been measured or are planned for measurement in blood and/or urine samples collected as part of the Canadian Health Measures Survey (CHMS) from 2007 to 2015. The chemicals were selected based on known or suspected health effects resulting from exposure, level of public concern, evidence of exposure in the Canadian population, and technical feasibility and cost of measurement. In addition, factors such as emerging Health Canada priorities are considered while selecting chemicals for inclusion in the CHMS. Summary data for these chemicals have been published in Health Canada's reports on human biomonitoring of environmental chemicals in Canada and scientific articles. The primary source of summary data for each chemical, when available, is provided in the table below.

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Organization: Health Canada

Date published: August 2017

Summary of chemicals measured in cycles 1 to 4 of the Canadian Health Measures Survey including data sources.
Chemical Cycle 1
2007-09
(6-79 years)
Cycle 2
2009-11
(3-79 years)
Cycle 3
2012-13
(3-79 years)
Cycle 4
2014-15
(3-79 years)
Acrylamide
Acrylamide haemoglobin adduct - - HC, 2015 HC, 2017
Glycidamide haemoglobin adduct - - HC, 2015 HC, 2017
Chlorophenols
2,4-Dichlorophenol HC, 2010 HC, 2013 - -
2,5-Dichlorophenol - HC, 2013 - -
2,4,5-Trichlorophenol - HC, 2013 - -
2,4,6-Trichlorophenol - HC, 2013 - -
Pentachlorophenol - HC, 2013 - -
Dioxins
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Rawn et al., 2012 - NA NA
1,2,3,7,8-Pentachlorodibenzo-p-dioxin (PeCDD) Rawn et al., 2012 - NA NA
1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin (HxCDD) Rawn et al., 2012 - NA NA
1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (HxCDD) Rawn et al., 2012 - NA NA
1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (HxCDD) Rawn et al., 2012 - NA NA
1,2,3,4,6,7,8-Heptachlorodibenzo-p-dioxin (HpCDD) Rawn et al., 2012 - NA NA
1,2,3,4,6,7,8,9-Octachlorodibenzo-p-dioxin (OCDD) Rawn et al., 2012 - NA NA
Environmental phenols and triclocarban
Bisphenol A HC, 2010 HC, 2013 HC, 2015 HC, 2017
Triclocarban - HC, 2013 - -
Triclosan - HC, 2013 HC, 2015 HC, 2017
Furans
2,3,7,8-Tetrachlorodibenzofuran (TCDF) Rawn et al., 2012 - NA NA
1,2,3,7,8-Pentachlorodibenzofuran (PeCDF) Rawn et al., 2012 - NA NA
2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) Rawn et al., 2012 - NA NA
1,2,3,4,7,8-Hexachlorodibenzofuran (HxCDF) Rawn et al., 2012 - NA NA
1,2,3,6,7,8-Hexachlorodibenzofuran (HxCDF) Rawn et al., 2012 - NA NA
2,3,4,6,7,8-Hexachlorodibenzofuran (HxCDF) Rawn et al., 2012 - NA NA
1,2,3,7,8,9-Hexachlorodibenzofuran (HxCDF) Rawn et al., 2012 - NA NA
1,2,3,4,6,7,8-Heptachlorodibenzofuran (HpCDF) Rawn et al., 2012 - NA NA
1,2,3,4,7,8,9-Heptachlorodibenzofuran (HpCDF) Rawn et al., 2012 - NA NA
1,2,3,4,6,7,8,9-Octachlorodibenzofuran (OCDF) Rawn et al., 2012 - NA NA
Metals and trace elements
Antimony HC, 2010 HC, 2013 - -
Arsenic Arsenic (total) HC, 2010 HC, 2013 - -
Arsenate - HC, 2013 HC, 2015 HC, 2017
Arsenite - HC, 2013 HC, 2015 HC, 2017
Arsenobetaine and arsenocholine - HC, 2013 HC, 2015 HC, 2017
Arsenocholine - - HC, 2015 HC, 2017
Dimethylarsinic acid - HC, 2013 HC, 2015 HC, 2017
Monomethylarsonic acid - HC, 2013 HC, 2015 HC, 2017
Cadmium HC, 2010 HC, 2013 HC, 2015 HC, 2017
Cesium - HC, 2013 - -
Cobalt - HC, 2013 - -
Copper HC, 2010 HC, 2013 - -
Fluoride - HC, 2013 HC, 2015 HC, 2017
Lead HC, 2010 HC, 2013 HC, 2015 HC, 2017
Manganese HC, 2010 HC, 2013 - -
Mercury Mercury (inorganic) HC, 2010 - HC, 2015 HC, 2017
Mercury (total) HC, 2010 HC, 2013 HC, 2015 HC, 2017
Methylmercury - - HC, 2015Table 1 footnote a HC, 2017
Molybdenum HC, 2010 HC, 2013 - -
Nickel HC, 2010 HC, 2013 - -
Selenium HC, 2010 HC, 2013 - -
Silver - HC, 2013 - -
Thallium - HC, 2013 - -
Tungsten - HC, 2013 - -
Uranium HC, 2010 HC, 2013 - -
Vanadium HC, 2010 HC, 2013 - -
Zinc HC, 2010 HC, 2013 - -
Organochlorines
Aldrin HC, 2010Table 1 footnote a - - -
α-Chlordane HC, 2010Table 1 footnote a - - -
γ-Chlordane HC, 2010Table 1 footnote a - - -
p,p'-Dichlorodiphenyldichloroethylene (p,p'-DDE) HC, 2010Table 1 footnote a - NA NA
p,p'-Dichlorodiphenyltrichloroethane (p,p'-DDT) HC, 2010Table 1 footnote a - - -
Endosulfan - - NA NA
Hexachlorobenzene HC, 2010Table 1 footnote a - NA NA
β-Hexachlorocyclohexane HC, 2010Table 1 footnote a - - -
γ-Hexachlorocyclohexane HC, 2010Table 1 footnote a - - -
cis-Nonachlor HC, 2010Table 1 footnote a - - -
trans-Nonachlor HC, 2010Table 1 footnote a - NA NA
Oxychlordane HC, 2010Table 1 footnote a - NA NA
Mirex HC, 2010Table 1 footnote a - - -
Toxaphene parlar 26 HC, 2010Table 1 footnote a - - -
Toxaphene parlar 50 HC, 2010Table 1 footnote a - - -
Parabens
Methyl paraben - - NA HC, 2017
Ethyl paraben - - NA HC, 2017
Propyl paraben - - NA HC, 2017
Butyl paraben - - NA HC, 2017
Perfluoroalkyl substances
Perfluoro-n-butyric acid (PFBA) - HC, 2013Table 1 footnote b - -
Perfluorohexanoic acid (PFHxA) - HC, 2013Table 1 footnote b - -
Perfluorooctanoic acid (PFOA) HC, 2010Table 1 footnote a HC, 2013Table 1 footnote b - -
Perfluorononanoic acid (PFNA) - HC, 2013Table 1 footnote b - -
Perfluorodecanoic acid (PFDA) - HC, 2013Table 1 footnote b - -
Perfluoroundecanoic acid (PFUnDA) - HC, 2013Table 1 footnote b - -
Perfluorobutane sulfonate (PFBS) - HC, 2013Table 1 footnote b - -
Perfluorohexane sulfonate (PFHxS) HC, 2010Table 1 footnote a HC, 2013Table 1 footnote b - -
Perfluorooctane sulfonate (PFOS) HC, 2010Table 1 footnote a HC, 2013Table 1 footnote b - -
Pesticides
Carbamate insectide metabolites Carbofuranphenol - HC, 2013 - -
2-Isopropoxyphenol - HC, 2013 - -
Organophosphate insecticides and metabolites Acephate - - NA -
Diethylphosphate (DEP) HC, 2010 HC, 2013 - -
Diethylthiophosphate (DETP) HC, 2010 HC, 2013 - -
Diethyldithiophosphate (DEDTP) HC, 2010 HC, 2013 - -
Dimethylphosphate (DMP) HC, 2010 HC, 2013 - -
Dimethylthiophosphate (DMTP) HC, 2010 HC, 2013 - -
Dimethyldithiophosphate (DMDTP) HC, 2010 HC, 2013 - -
Malathion dicarboxylic acid - - NA HC, 2017
Methamidophos - - NA -
3,5,6 Trichloro-2-pyridinol - - NA HC, 2017
Phenoxy herbicide 2,4-Dichlorophenoxyacetic acid (2,4-D) HC, 2010 HC, 2013 - -
Pyrethroid insecticide metabolites cis-3-(2,2-Dibromovinyl)-2,2-dimethylcyclopropane carboxylic acid (cis-DBCA) HC, 2010 HC, 2013 - -
cis-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid (cis-DCCA) HC, 2010 HC, 2013 - -
trans-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid (trans-DCCA) HC, 2010 HC, 2013 - -
4-Fluoro-3-phenoxybenzoic acid (4-F-3-PBA) HC, 2010 HC, 2013 - -
3-Phenoxybenzoic acid (3-PBA) HC, 2010 HC, 2013 - -
Triazine herbicide metabolites Atrazine mercapturate - HC, 2013 - -
Desethylatrazine - HC, 2013 - -
Diaminochlorotriazine - HC, 2013 - -
Phthalate metabolites
Mono benzyl phthalate (MBzP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono-3-carboxypropyl phthalate (MCPP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono cyclohexyl phthalate (MCHP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono-2-ethylhexyl phthalate (MEHP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono ethyl phthalate (MEP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono-iso-butyl phthalate (MiBP) - HC, 2013 - -
Mono-isononyl phthalate (MiNP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono-methyl phthalate (MMP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono-n-butyl phthalate (MnBP) HC, 2013Table 1 footnote c HC, 2013 - -
Mono-n-octyl phthalate (MOP) HC, 2013Table 1 footnote c HC, 2013 - -
Polybrominated flame retardants
2,2',4,4',5,5'-Hexabromobiphenyl (PBB 153) HC, 2010Table 1 footnote a - - -
4,4'-Dibromodiphenyl ether (PBDE 15) HC, 2010Table 1 footnote a, Rawn et al., 2014 - - -
2,2',4-Tribromodiphenyl ether (PBDE 17) HC, 2010Table 1 footnote a, Rawn et al., 2014 - - -
2,3',4-Tribromodiphenyl ether (PBDE 25) HC, 2010Table 1 footnote a - - -
2,4,4'-Tribromodiphenyl ether (PBDE 28) HC, 2010Table 1 footnote a, Rawn et al., 2014 - - -
2',3,4'-Tribromodiphenyl ether (PBDE 33) HC, 2010Table 1 footnote a - - -
3,4,4'-Tribromodiphenyl ether (PBDE 37) Rawn et al., 2014 - - -
2,2',4,4'-Tetrabromodiphenyl ether (PBDE 47) HC, 2010Table 1 footnote a, Rawn et al., 2014 - NA NA
2,3',4,4'-Tetrabromodiphenyl ether (PBDE 66) Rawn et al., 2014 - - -
2,3',4',6-Tetrabromodiphenyl ether (PBDE 71) Rawn et al., 2014 - - -
2,4,4',6-Tetrabromodiphenyl ether (PBDE 75) Rawn et al., 2014 - - -
3,3',4,4'-Tetrabromodiphenyl ether (PBDE 77) Rawn et al., 2014 - - -
2,2',3,4,4'-Pentabromodiphenyl ether (PBDE 85) Rawn et al., 2014 - - -
2,2',4,4',5-Pentabromodiphenyl ether (PBDE 99) HC, 2010Table 1 footnote a, Rawn et al., 2014 - NA NA
2,2',4,4',6-Pentabromodiphenyl ether (PBDE 100) HC, 2010Table 1 footnote a, Rawn et al., 2014 - NA NA
2,3',4,4',6-Pentabromodiphenyl ether (PBDE 119) Rawn et al., 2014 - - -
3,3',4,4',5-Pentabromodiphenyl ether (PBDE 126) Rawn et al., 2014 - - -
2,2',3,4,4',5'-Hexabromodiphenyl ether (PBDE 138) Rawn et al., 2014 - - -
2,2',4,4',5,5'-Hexabromodiphenyl ether (PBDE 153) HC, 2010Table 1 footnote a, Rawn et al., 2014 - NA NA
2,2',4,4',5,6'-Hexabromodiphenyl ether (PBDE 154) Rawn et al., 2014 - - -
2,3,3',4,5,6-Hexabromodiphenyl ether (PBDE 160) Rawn et al., 2014 - - -
2,2',3,4,4',5,6-Heptabromodiphenyl ether (PBDE 181) Rawn et al., 2014 - - -
2,2',3,4,4',5',6-Heptabromodiphenyl ether (PBDE 183) Rawn et al., 2014 - - -
2,3,3',4,4',5,6-Heptabromodiphenyl ether (PBDE 190) Rawn et al., 2014 - - -
2,3,3',4,4',5,5',6-Octabromodiphenyl ether (PBDE 205) Rawn et al., 2014 - - -
2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (PBDE 209) Rawn et al., 2014 - NA NA
Hexabromocyclododecane α (HBCD α) Rawn et al., 2014 - NA NA
Hexabromocyclododecane β (HBCD β) Rawn et al., 2014 - NA NA
Hexabromocyclododecane γ (HBCD γ) Rawn et al., 2014 - NA NA
Tetrabromobisphenol A (TBBPA) - - NA NA
Polychlorinated biphenyls (PCBs)
Aroclor 1260 HC, 2010Table 1 footnote a - - -
2,2',5-Trichlorobiphenyl (PCB 18) Rawn et al., 2012 - - -
2,4,4'-Trichlorobiphenyl (PCB 28) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,2',4,5'-Tetrachlorobiphenyl (PCB 49) Rawn et al., 2012 - - -
2,2',5,5'-Tetrachlorobiphenyl (PCB 52) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,3',4,4'-Tetrachlorobiphenyl (PCB 66) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,4,4',5-Tetrachlorobiphenyl (PCB 74) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
3,3',4,4'-Tetrachlorobiphenyl (PCB 77) Rawn et al., 2012 - NA NA
3,4,4',5-Tetrachlorobiphenyl (PCB 81) Rawn et al., 2012 - NA NA
2,2',4,4',5-Pentachlorobiphenyl (PCB 99) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2,2',4,5,5'-Pentachlorobiphenyl (PCB 101) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,3,3',4,4'-Pentachlorobiphenyl (PCB 105) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2,3,3',4',6-Pentachlorobiphenyl (PCB 110) Rawn et al., 2012 - - -
2,3,3',4,4'-Pentachlorobiphenyl (PCB 114) Rawn et al., 2012 - NA NA
2,3',4,4',5-Pentachlorobiphenyl (PCB 118) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2',3,4,4',5-Pentachlorobiphenyl (PCB 123) Rawn et al., 2012 - NA NA
3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Rawn et al., 2012 - NA NA
2,2',3,3',4,4'-Hexachlorobiphenyl (PCB 128) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,2',3,4,4',5'-Hexachlorobiphenyl (PCB 138) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2,2',3,4,5,5'-Hexachlorobiphenyl (PCB 141) Rawn et al., 2012 - - -
2,2',3,4',5,5'-Hexachlorobiphenyl (PCB 146) HC, 2010Table 1 footnote a - NA NA
2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2,3,3',4,4',5-Hexachlorobiphenyl (PCB 156) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2,3,3',4,4',5'-Hexachlorobiphenyl (PCB 157) Rawn et al., 2012 - NA NA
2,3,3',4',5,6-Hexachlorobiphenyl (PCB 163) HC, 2010Table 1 footnote a - - -
2,3',4,4',5,5'-Hexachlorobiphenyl (PCB 167) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
3,3',4,4',5,5'-Hexachlorobiphenyl (PCB 169) Rawn et al., 2012 - NA NA
2,2',3,3',4,4',5-Heptachlorobiphenyl (PCB 170) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2,2',3,3',5,5',6-Heptachlorobiphenyl (PCB 178) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,2',3,4,4',5,5'-Heptachlorobiphenyl (PCB 180) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2,2',3,4,4',5',6-Heptachlorobiphenyl (PCB 183) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,2',3,4',5,5',6-Heptachlorobiphenyl (PCB 187) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2,3,3',4,4',5,5'-Heptachlorobiphenyl (PCB 189) Rawn et al., 2012 - NA NA
2,2',3,3',4,4',5,5'-Octachlorobiphenyl (PCB 194) HC, 2010Table 1 footnote a, Rawn et al., 2012 - NA NA
2,2',3,3',4,4',5,6-Octachlorobiphenyl (PCB 195) Rawn et al., 2012 - - -
2,2',3,3',4,5,5',6-Octachlorobiphenyl (PCB 201) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,2',3,4,4',5,5',6-Octachlorobiphenyl (PCB 203) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,2',3,3',4,4',5,5',6-Nonachlorobiphenyl (PCB 206) HC, 2010Table 1 footnote a, Rawn et al., 2012 - - -
2,2',3,3',4,4',5,5',6,6'-Decachlorobiphenyl (PCB 209) Rawn et al., 2012 - - -
Polycyclic aromatic hydrocarbon metabolites
Benzo[a]pyrene metabolite 3-Hydroxybenzo[a]pyrene - HC, 2013 HC, 2015 HC, 2017
Chrysene metabolites 2-Hydroxychrysene - HC, 2013 HC, 2015 HC, 2017
3-Hydroxychrysene - HC, 2013 HC, 2015 HC, 2017
4-Hydroxychrysene - HC, 2013 HC, 2015 HC, 2017
6-Hydroxychrysene - HC, 2013 HC, 2015 HC, 2017
Fluoranthene metabolite 3-Hydroxyfluoranthene - HC, 2013 HC, 2015 HC, 2017
Fluorene metabolites 2-Hydroxyfluorene - HC, 2013 HC, 2015 HC, 2017
3-Hydroxyfluorene - HC, 2013 HC, 2015 HC, 2017
9-Hydroxyfluorene - HC, 2013 HC, 2015 HC, 2017
Napthalene metabolites 1-Hydroxynaphthalene - HC, 2013 HC, 2015 HC, 2017
2-Hydroxynaphthalene - HC, 2013 HC, 2015 HC, 2017
Phenanthrene metabolites 1-Hydroxyphenanthrene - HC, 2013 HC, 2015 HC, 2017
2-Hydroxyphenanthrene - HC, 2013 HC, 2015 HC, 2017
3-Hydroxyphenanthrene - HC, 2013 HC, 2015 HC, 2017
4-Hydroxyphenanthrene - HC, 2013 HC, 2015 HC, 2017
9-Hydroxyphenanthrene - HC, 2013 HC, 2015 HC, 2017
Pyrene metabolite 1-Hydroxypyrene - HC, 2013 HC, 2015 HC, 2017
Tobacco biomarkers
Nicotine and metabolites Anabasine (free) - - NA -
Anabasine (total) NA - - -
Cotinine (free) HC, 2010 HC, 2013 HC, 2015 HC, 2017
Cotinine (total) NA - - -
Cotinine-n-glucuronide NA - NA -
Nicotine (free) - - NA -
Nicotine (total) NA - - -
Nicotine-n-glucuronide NA - NA -
trans-3-Hydroxycotinine (free) - - NA -
trans-3-Hydroxycotinine (total) NA - - -
trans-3-Hydroxycotinine-glucuronide NA - NA -
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) NNAL (free) NA - NA -
NNAL (total) NA - NA -
Volatile organic compounds
Ethylbenzene - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
Styrene - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
Toluene - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
m- & p-Xylenes - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
o-Xylene - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
Benzene and metabolites Benzene - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
trans, trans-Muconic acid - HC, 2013 HC, 2015 HC, 2017Table 1 footnote b
Phenol - HC, 2013 - -
S-Phenylmercapturic acid - HC, 2013 HC, 2015 HC, 2017Table 1 footnote b
Chlorinated hydrocarbons 1,1,2-Trichloroethylene - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
1,1,1,2-Tetrachloroethylene - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
Trihalomethanes Bromodichloromethane - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
Dibromochloromethane - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
Tribromomethane - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
Trichloromethane - - HC, 2015Table 1 footnote b HC, 2017Table 1 footnote b
General characterization
Creatinine HC, 2010 HC, 2013 HC, 2015 HC, 2017
Specific gravity - NA NA NA
 

Table 1 - Abbrevations

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