Health Science Publications

In this section you will find summaries of research projects recently completed by scientists and researchers within Health Canada. The results of federal research, aimed at protecting the health of Canadians and their environments, will contribute to evidence-based decision making, programs and/or policy. This site will be periodically updated with information on the latest research coming out of the Department.

Acoustics

• Chronic noise exposure in the spontaneously hypertensive rat
• Prevalence of hearing loss among Canadians aged 20 to 79: Audiometric results from the 2012/2013 Canadian Health Measures Survey
• Prevalence of hearing loss among a representative sample of Canadian children and adolescents, 3 to 19 years of age
• Wind turbine sound pressure level calculations at dwellings
• Wind turbine sound power measurements
• Estimating annoyance to calculated wind turbine shadow flicker is improved when variables associated with wind turbine noise exposure are considered
• Personal and situational variables associated with wind turbine noise annoyance
• Exposure to wind turbine noise: Perceptual responses and reported health effects
• Self-reported and measured stress responses associated with exposure to wind turbine noise
• Effects of Wind Turbine Noise on Self-Reported and Objective Measures of Sleep
• An assessment of quality of life using the WHOQOL-BREF among participants living in the vicinity of wind turbines
• Self-Reported and Objectively Measured Health Indicators among a Sample of Canadians Living within the Vicinity of Industrial Wind Turbines: Social Survey and Sound Level Modelling Methodology
• MP3 Player Listening Sound Pressure Levels among 10 to 17 year old Students

Biotechnology

• Breast cancer detection and survival among women with cosmetic breast implants: Systematic review and meta-analysis of observational studies
• Early Murine Immune Responses from Endotracheal Exposures to Biotechnology-Related Bacillus Strains

Nanotechnology

• In Vitro Immunotoxicology of Quantum Dots and Comparison with Dissolved Cadmium and Tellurium
• Cadmium telluride quantum dot nanoparticle cytotoxicity and effects on model immune responses to Pseudomonas aeruginosa
• Cadmium telluride quantum dots cause oxidative stress leading to extrinsic and intrinsic apoptosis in hepatocellular carcinoma HepG2 cells
• Comparison of toxicity of uncoated and coated silver nanoparticles
• Critical Experimental Parameters Related to the Cytotoxicity of Zinc Oxide Nanoparticles
• Synthesis and Physicochemical Characterization of Mesoporous Nanoparticles
• Nanosilver Cytotoxicity in Rainbow Trout (Oncorhynchus mykiss) Erythrocytes and Hepatocytes
• Carbon Black Nanoparticle Instillation Induces Sustained Inflammation and Genotoxicity in Mouse Lung and Liver
• Pulmonary Response to Surface-Coated Nanotitanium Dioxide Particles Includes Induction of Acute Phase Response Genes, Inflammatory Cascades, and Changes in Micrornas: A Toxicogenomic Study
• Poly(Ethylene Imine) Nanocarriers do not Induce Mutations nor Oxidative DNA Damage In Vitro in Mutamouse Fe1 Cells
• Mutation Spectrum in Fe1-Muta™ Mouse Lung Epithelial Cells Exposed to Nanoparticulate Carbon Black

Tobacco

• In vitro exposure to cigarette smoke induces oxidative stress in follicular cells of F1 hybrid mice
• IL-1 Receptor Regulates microRNA-135b Expression in a Negative Feedback Mechanism during Cigarette Smoke-Induced Inflammation
• A Global Toxicogenomic Analysis Investigating the Mechanistic Differences between Tobacco and Marijuana Smoke Condensates in vitro
• Mutagenicity of Smoke Condensates from Canadian Cigarettes with Different Design Features
• Assessment of Validity of Self-Reported Smoking Status
• Sidestream Tobacco Smoke is a Male Germ Cell Mutagen
• Genetic Toxicology and Toxicogenomic Analysis of Three Cigarette Smoke Condensates In Vitro Reveals Few Differences Among Full-Flavor, Blonde, and Light Products
• The Analysis of Mainstream Smoke Emissions Of Canadian 'Super Slim' Cigarettes