National case definition: Yellow fever

Date of last revision/review: May 2008

National notification

Only confirmed cases of disease should be notified.

Type of surveillance

Routine case-by-case notification to the federal level

Case classification

Confirmed case

Clinical illness with laboratory confirmation of infection:

Probable case

Clinical illness with laboratory evidence of infection:

Clinical evidence

Yellow fever is a mosquito-borne viral illness characterized by acute onset of fever and constitutional symptoms followed by a brief remission and a recurrence of fever, hepatitis, albuminuria and, in some instances, renal failure, shock and generalized hemorrhages.

ICD code(s)

ICD-10 code(s): A95

ICD-9 code(s): 060

Type of international reporting

Under Article 6 of the International Health Regulations (IHR) (2005), each State Party shall notify the World Health Organization (WHO) by way of the IHR National Focal Point,Footnote 1  and within 24 hours of assessment of public health information, of all events which may constitute a public health emergency of international concern within its territory in accordance with the decision instrument (Annex 2 of the IHRFootnote 2), as well as any health measure implemented in response to those events.

Note: If event does not meet the criteria for notification under Article 6 of the IHR, then other IHR-related reporting requirements may still apply with WHO and/or other States Parties, including those under Art. 7 (information-sharing during unexpected or unusual public health events), Art. 8 (consultation with WHO on public health events), Art. 9 (any public health risk that may cause international disease spread), Art. 10 (requests for verification from WHO), and Art 44 (collaboration and assistance). 


Probable case definitions are provided as guidelines to assist with case finding and public health management, and are not for national notification purposes.


Footnote 1

In Canada, the IHR National Focal Point is located at the Public Health Agency of Canada.

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Footnote 2

IHR Annex 2 Decision Instrument is on pages 43-46 of the IHR Third Edition (2005):

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