72 Substances identified as being of low concern
These substances were identified for action under the Chemicals Management Plan (CMP). The final screening assessment incorporates results from the Science Approach Document: Ecological Risk Classification of Organic Substances and the Science Approach Document: Threshold of Toxicological Concern (TTC)-based Approach for Certain Substances.
|Final screening assessment||Conclusion on section 64 criteria||Follow-up activities|
|HTML||Do not meet||CAS RNs 111-96-6 and 112-49-2: Significant new activity (SNAc) provisions|
While exposure to any of the 72 substances is not of concern at current levels, 2 substances (CAS RNs 111-96-6 and 112-49-2) have been identified as having potential health effect of concern. Therefore, there may be a concern if exposure levels were to increase. For this reason, the Government of Canada has applied the SNAc provisions of the Canadian Environmental Protection Act, 1999 (CEPA 1999) to these 2 substances.
|August 3, 2022||Publication in the Canada Gazette, Part II: Vol. 156, No. 16 of an order amending the Domestic Substances List (DSL) to apply the SNAc provisions of the CEPA 1999 to CAS RNs 111-96-6 and 112-49-2.|
|November 3, 2018||Publication in the Canada Gazette, Part I: Vol. 152, No. 44 and start of 60-day public comment period on a notice of intent to amend the DSL to apply the SNAc provisions of CEPA 1999 to CAS RNs 111-96-6 and 112-49-2.|
|November 3, 2018||Publication of the final screening assessment. The related notice was published in the Canada Gazette, Part I: Vol. 152, No. 44.|
|June 17, 2017||Publication and start of 60-day public comment period on the draft screening assessment (including follow-up activities for 36 of the 74 substances). The related notice was published in the Canada Gazette, Part I: Vol. 151, No. 24.|
Combining the results from both approaches, 75 substances were identified to be of low concern for human health and ecological risk. One substance (CAS RN 118-96-7) was later found to be associated with an international classification for carcinogenicity based on empirical data with positive results, thereby excluding it from the TTC-based approach. This substance was assessed in the Final Screening Assessment for the Rapid Screening of Substances with Limited General Population Exposure.
Also, as a result of new information on uses and volumes submitted pursuant to a CEPA 1999 section 71 notice, 2 additional substances (CAS RNs 4979-32-2 and 94270-86-7) that were included in the draft of this screening assessment have been removed for further assessment due to potential human health concerns. These substances are being assessed as a part of the Benzotriazoles and Benzothiazoles Group.
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