Hexamethylenetetramines Group

These substances were identified for action under the Chemicals Management Plan (CMP). The screening assessment focuses on 3 substances referred to collectively as the Hexamethylenetetramines Group.

Summary of publications
Substance group CAS RN Common name DSL name Draft screening assessment Risk management scope Proposed conclusion on section 64 criteria Follow-up activities
Hexamethylenetetramines Group 4080-31-3Footnote a Quaternium-15Footnote b
3,5,7-Triaza-1-azoniatricyclo[³,7]decane, 1-(3-chloro-2-propenyl)-, chloride HTML HTML Meets one or more of the criteria Refer to risk management scope
51229-78-8Footnote c Quaternium-15Footnote d
3,5,7-Triaza-1-azoniatricyclo[³,7]decane, 1-(3-chloro-2-propenyl)-, chloride, (Z)-
58713-21-6Footnote c Methenamine hydrochloride 1,3,5,7-Tetraazatricyclo[³,7]decane, hydrochloride None Does not meet None planned at this time
Footnote 1

This CAS RN is a mixture of cis- and trans-1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride (CTAC).

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Footnote 2

According to the European Commission database for information on cosmetic substances and ingredients (CosIng), "Quaternium-15" is represented by CAS RN 4080-31-3 or by a mixture containing CAS RN 4080-31-3 and CAS RN 51229-78-8.

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Footnote 3

This substance was not identified under subsection 73(1) of the Canadian Environmental Protection Act, 1999 but was included in this assessment as it was considered a priority on the basis of other human health concerns.

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Footnote 4

The Scientific Committee on Consumer Safety in Europe (SCCS) uses the term "Quaternium-15" to refer to cis-CTAC (CAS RN 51229-78-8).

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Date Activity
March 2022 Anticipated publication of the final screening assessment and proposed risk management approach.
March 6, 2021 Publication and start of 60-day public comment period on the Draft Screening Assessment for the Hexamethylenetetramines Group and the Risk Management Scope for Certain Substances in the Hexamethylenetetramines Group. The related notice was published in the Canada Gazette, Part I: Vol. 155, No. 10.

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