Pseudomonas aeruginosa (Strains ATCC 31480, 700370, 700371)

Strain Number ATCC 31480, 700370 and 700371

What are they?

  • Pseudomonas aeruginosa strains ATCC 31480, 700370 and 700371 are industrial strains of a micro-organism that can be found in a large number of different areas in nature, including soil, water, and as one of many bacteria normally present on various plants and animals.
  • Pseudomonas aeruginosa is known as an occasional pathogen of humans, plants and animals that may cause disease but, under normal circumstances, is unlikely to be a serious hazard.

How are they used?

  • Globally, Pseudomonas aeruginosa has potential uses in various industrial and commercial sectors. These include waste degradation, particularly in oil refineries, but also in the textile, pulp and paper, mining and explosives industries. They can also potentially be used in commercial and household drain cleaners and degreasers, septic tank additives and general cleaning products and odor control products.
  • Pseudomonas aeruginosa ATCC 31480, 700370 and 700371 are no longer manufactured in or imported into Canada except for controlled use in research and development.

Why is the Government of Canada assessing them?

  • Micro-organisms on the Domestic Substances List (DSL) must undergo an assessment to determine whether they have the potential to cause harm to human health or the environment.
  • Pseudomonas aeruginosa strains ATCC 31480, ATCC 700370 and ATCC 700371 were nominated and added to the DSL because they were manufactured in or imported into Canada between January 1, 1984 and December 31, 1986 and they entered or were released into the environment without being subject to conditions under the Canadian Environmental Protection Act,1999 (CEPA 1999) or any other federal or provincial legislation.
  • The Minister of the Environment and the Minister of Health are therefore required to conduct screening assessments of living organisms on the DSL under Section 74 (b) of CEPA 1999 in order to determine whether they have the potential to cause harm to human health or the environment.
  • These three strains were identified as a high priority for assessment based on potential hazard criteria, such as pathogenicity or toxicity to humans and non-human species.

How are they released to the environment?

  • The Government of Canada has reviewed information that indicates that Pseudomonas aeruginosa ATCC 31480, 700370 and 700371 are not currently in commerce in Canada.
  • As a result, it is unlikely that Pseudomonas aeruginosa ATCC 31480, 700370 and 700371 are entering the environment as a result of commercial manufacture, import or use in this country.

How are Canadians exposed to them?

  • The general population in Canada is not expected to be exposed from commercial or consumer uses to Pseudomonas aeruginosa ATCC 31480, 700370 and 700371 since these strains are no longer imported into, or manufactured in, Canada for commercial or consumer uses.

What are the results of the assessment?

  • The Government of Canada has conducted a science-based evaluation of Pseudomonas aeruginosa ATCC 31480, 700370 and 700371, called a screening assessment.
  • Screening assessments address potential for harm to the general population in Canada (not including workplace exposures) and the environment.
  • There are currently no commercial activities with these strains in Canada, and hence no exposure is expected.
  • Results of the final screening assessment indicate that Pseudomonas aeruginosa ATCC 31480, 700370 and 700371 are not considered to be harmful to the health of the general population at current levels of exposure.
  • The Government of Canada has therefore concluded that Pseudomonas aeruginosa ATCC 31480, 700370 and 700371 are not entering the environment in a quantity or under conditions that constitute a danger to the environment.

What is the Government of Canada doing?

  • Although the exposure of the general population of Canada to Pseudomonas aeruginosa ATCC 31480, 700370 and 700371 is not expected, the Government of Canada proposed actions so that exposure remains low.
  • Significant New Activity (SNAc) provisions to these substances will be applied. This would require that any proposed new manufacture, import or use be subject to further assessment and risk management consideration.
  • The final screening assessment report for Pseudomonas aeruginosa ATCC 31480, 700370 and 700371 was published on June 9, 2012.

What can Canadians do?

  • The health risks associated with a micro-organism depend on the hazard (its potential to cause health effects) and the exposure (the amount and the manner in which you are exposed). Pseudomonas aeruginosa ATCC 31480, 700370 and 700371 are not presently a concern for the environment or human health at current levels of exposure.
  • Individuals who handle Pseudomonas aeruginosa ATCC 31480, 700370 and 700317 in the workplace (i.e., laboratory and research and development facilities) should consult with their occupational health and safety representative about safe handling practices, applicable laws and requirements under the Workplace Hazardous Materials Information System and the Laboratory Biosafety Guidelines.
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