Pseudomonas putida - information sheet
Strain ATCC 12633
Strain ATCC 31483
Strain ATCC 31800
Strain ATCC 700369
On this page
- Overview
- About these organisms
- Exposure of Canadians and the environment
- Key health and ecological effects (hazard)
- Risk assessment outcomes
- Preventive actions and reducing risk
- Important to know
Overview
- The Government of Canada conducted a science-based evaluation of Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369, called a screening assessment, to address the potential for harm to Canadians and the environment.
- Under the Canadian Environmental Protection Act, 1999 (CEPA 1999), the risk posed by a substance is determined by considering both its hazardous properties (its potential to cause adverse human health or ecological effects) and the amount of exposure there is to people or to the environment. A substance may have hazardous properties; however, the risk to human health or to the environment may be low depending upon the level of exposure.
- More information on assessing risk can be found in the Framework for Science-Based Risk Assessment of Micro-Organisms Regulated under the Canadian Environmental Protection Act, 1999.
- Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 are not hazardous to the health of the general Canadian population or to the environment, but some concerns were identified for susceptible individuals. Exposure of Canadians and the environment was concluded to be medium. Therefore, it is concluded that these strains are not harmful to human health or to the environment.
About these organisms
- This screening assessment focuses on 4 strains of the organism Pseudomonas putida (ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369). These Priority B (medium hazard) organisms were assessed as part of the micro-organisms initiative of the Chemicals Management Plan (CMP).
- Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 are strains of bacteria that could have a number of consumer, commercial and industrial uses. The characteristics of Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 make them suitable for use in various applications, including bioremediation and biodegradation, water and waste water treatment, cleaning and degreasing products, and in the production of enzymes and biochemicals.
- Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 were reported to be manufactured in, or imported into, Canada.
Exposure of Canadians and the environment
- Exposure of Canadians is expected from the application of products available to consumers, such as septic tank or recreational vehicle tank additives, pond or aquarium treatment products, or drain cleaning or degreasing products.
- Use of these organisms in biodegradation and bioremediation applications will result in their release to the soil, and effluent discharge from wastewater treatment, degreasing or drain cleaning could result in their release to aquatic environments.
Key health and ecological effects (hazard)
- In humans, the species Pseudomonas putida is considered to be a rare opportunistic pathogen, causing bloodstream, traumatic wound, soft tissue and cornea infections in patients who are immunosuppressed, have debilitating health conditions or whose normal barriers to infection have been breached as the result of surgical procedures, indwelling medical devices or physical trauma.
- Antibiotic resistance of some strains has been reported and could limit effective treatment; however, Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and 700369 are susceptible to several antibiotics.
- The key human health effects of concern are associated with contamination of blood products and medical devices with Pseudomonas putida.
- Some strains of Pseudomonas putida are reported to be opportunistic fish pathogens. Adverse effects are mainly observed in farm-raised, ornamental or otherwise domesticated fish populations. Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 have not been associated with adverse effects in the environment.
Risk assessment outcomes
- Considering all information presented in this assessment, the risk to human health from Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 is low.
- Also considering all information presented, there is low risk of harm to organisms and the broader integrity of the environment from Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369.
- The Government of Canada published the Final Screening Assessment for Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 on January 21, 2017.
Screening assessment conclusions
- As a result of this screening assessment, the Government concluded that Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 are not harmful to human health at current levels of exposure.
- The Government also concluded that Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 are not entering the environment at levels that are harmful to the environment.
Preventive actions and reducing risk
- Although Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 are not considered to be harmful to human health or to the environment at current levels of exposure, they could become harmful to human health if exposure were to increase. Consequently, the Government has applied the Significant New Activity (SNAc) provisions of CEPA 1999 to Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369.
- The SNAc provisions require a person (individual or corporation) proposing to use this organism in a health care setting or in a consumer product to submit prescribed information to the Government for assessment of potential risks to human health in relation to the proposed new activity. If risks are identified, the Government can take action to manage them.
- Further information and updates on risk management actions can be found in the CMP risk management actions table.
Important to know
- Pseudomonas putida strains ATCC 12633, ATCC 31483, ATCC 31800 and ATCC 700369 can be found in products available to consumers. Canadians should follow any safety warnings and directions on product labels and dispose of products responsibly.
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