Tier 3 drug shortages

Tier 3 shortages are those that have the greatest potential impact on Canada's drug supply and health care system. Medical necessity and low availability of alternative supplies, ingredients or therapies determine the degree of impact.

The Tier Assignment Committee (TAC) includes federal, provincial and territorial governments, health care professionals and industry stakeholders. TAC makes recommendations on the tier assignment of actual and anticipated drug shortages based on:

Drugs in or at risk of Tier 3 shortages may be eligible for exceptional importation and sale. For more information, please consult the Guide to the exceptional importation and sale of drugs in response to drug shortages (GUI-0148).

Drugs that are allowed to be imported and sold in order to mitigate a critical shortage are found on the List of drugs for exceptional importation and sale.

Drug (Active Ingredient) Date of Tier 3 Determination TAC Committee Membership Used in the treatment of COVID-19 and/or related conditions (Yes/No)
Mepivacaine hydrochloride injection, 20 mg/mL June 7, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Anesthesiologists Society No
Loxapine hydrochloride; Loxapine succinate May 17, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Society of Hospital Pharmacists, Canadian Psychiatric Association No
Epinephrine injection 1 mg/10 mL pre-filled syringes June 19, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association,
Canadian Society of Hospital Pharmacists
No
Carbamazepine Controlled Release, tablets May 10, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian League Against Epilepsy No
Bupivacaine with Epinephrine May 7, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society Hospital Pharmacists, Canadian Anesthesiologists' Society No
Abatacept solution for subcutaneous injection April 22, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Rheumatology Association No
Thiamine Hydrochloride, 100 MG/ML February 27, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists No
Pantoprazole Sodium for Injection June 20, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Gastroenterology No
Colesevelam Proactively assigned, February 15, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Society of Hospital Pharmacists, Canadian Association of Gastroenterology No
Tamsulosin Hydrochloride January 26, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Urological Association No
Cholestyramine January 26, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Society of Hospital Pharmacists, Canadian Association of Gastroenterology No
Colestipol Proactively assigned January 26, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Society of Hospital Pharmacists, Canadian Association of Gastroenterology No
Aminophylline March 19, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Cardiovascular Society No
Bupivacaine January 18, 2024 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society Hospital Pharmacists, Canadian Anesthesiologists' Society No
Prazosin 1mg, 2mg, 5mg Tablets May 19, 2023 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Pharmacists Association, Canadian Cardiovascular Society, Department of National Defence No
Glucagon for Injection, rDNA origin April 20, 2023 Health Canada, British Columbia Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Pediatric Endocrine Group, Canadian Society of Endocrinology and Metabolism No
Argatroban for Injection May 8, 2023 Health Canada, British Columbia Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Hematology Society No
Apomorphine Hydrochloride November 14, 2023 Health Canada, British Columbia - Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Parkinson Canada No
Eluxadoline - Viberzi September 20, 2022 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Ontario Association of Gastroenterology No
Calcium Chloride Injection August 24, 2023 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists No
Dextrose Injection August 24, 2023 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists No

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