Tier 3 drug shortages

Tier 3 shortages are those that have the greatest potential impact on Canada's drug supply and health care system. Medical necessity and low availability of alternative supplies, ingredients or therapies determine the degree of impact.

The Tier Assignment Committee (TAC) includes federal, provincial and territorial governments, health care professionals and industry stakeholders. TAC makes recommendations on the tier assignment of actual and anticipated drug shortages based on:

Drugs in or at risk of Tier 3 shortages may be eligible for exceptional importation and sale. For more information, please consult the Guide to the exceptional importation and sale of drugs in response to drug shortages (GUI-0148).

Drugs that are allowed to be imported and sold in order to mitigate a critical shortage are found on the List of drugs for exceptional importation and sale.

Drug (Active Ingredient) Date of Tier 3 Determination TAC Committee Membership Used in the treatment of COVID-19 and/or related conditions (Yes/No)
Sodium Thiosulfate – Technetium TC 99M TSC May 6, 2022 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Nuclear Medicine No
Hydrocortisone Tablets (Cortef) April 25, 2022 Health Canada, British Columbia Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Endocrinology and Metabolism No
Sterile Water for Injection (small volume formats) March 17, 2022 Health Canada, British Columbia Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Mohawk MedBuy, HealthPro Yes
Sodium Chloride 0.9% USP Injectable - Diluent January 20, 2022 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Public Health Agency of Canada Yes
Asparaginase - Erwinase July 16, 2020 Health Canada, Ontario Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Provincial Cancer Agencies No
Hydralazine Injection November 26, 2021 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association,
Canadian Society of Hospital Pharmacists, Canadian Cardiovascular Society
No
Iohexol Injection - Omnipaque (Iodinated Contrast Media) June 7, 2022 Health Canada, British Columbia Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Radiologists No
Iodixanol Injection - Visipaque (Iodinated Contrast Media) June 7, 2022 Health Canada, British Columbia Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Radiologists No
Medroxyprogesterone Acetate - Injectable suspension Proactively assigned March 18, 2021 Health Canada, Ontario Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Society of Obstetricians and Gynaecologists of Canada No
Methotrimeprazine Hydrochloride Injection February 17, 2022 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association,
Canadian Society of Hospital Pharmacists, Canadian Society of Palliative Care Physicians
No
Morphine Sulfate Capsules - Sustained-Release May 31, 2021 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association
Canadian Medical Association, Canadian Society of Addiction Medicine
No
Moxifloxacin Injection November 4, 2021 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Association of Medical Microbiology and Infectious Disease Canada No
Papaverine Hydrochloride Injection April 28, 2022 Health Canada, British Columbia Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Society of Cardiac Surgeons No
Potassium Acetate Injection June 16, 2022 Health Canada, British Columbia Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, No
Levofloxacin Injection November 4, 2021 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Association of Medical Microbiology and Infectious Disease Canada No
Remifentanil Hydrochloride Injection February 24, 2022 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Anesthesiology Society No
Sarilumab April 27, 2021 Health Canada, British Columbia Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Rheumatology Association, Canadian Society of Hospital Pharmacists Yes
Tocilizumab for Injection (IV) February 19, 2021 Health Canada, Ontario Ministry of Health representing the Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Pharmacists Association, Canadian Rheumatology Association Yes
Lurbinectedin (Zepzelca) Proactively assigned April 13, 2022 Health Canada, British Columbia Ministry of Health representing Provincial and Territorial Drug Shortage Task Team, Canadian Medical Association, Canadian Society of Hospital Pharmacists, Canadian Association of Provincial Cancer Agencies No
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