National case definition: Invasive Pneumococcal Disease
Invasive pneumococcal disease
Date of last revision/review: May 2008
Only confirmed cases of disease should be notified.
Type of surveillance
Routine case-by-case notification to the federal level
Enhanced case-by-case notification to International Circumpolar Surveillance in participating Northern regions
Enhanced active case-by-case notification by paediatric tertiary care hospitals involved in the Immunization Monitoring Program, Active (IMPACT)
- isolation of Streptococcus pneumoniae from a normally sterile site (excluding the middle ear and pleural cavity)
- demonstration of S. pneumoniae DNA from a normally sterile site (excluding the middle ear and pleural cavity)
- demonstration of S. pneumoniae antigen from a normally sterile site (excluding the middle ear and pleural cavity)
Clinical evidence of invasive disease (see Clinical evidence section) with laboratory confirmation of infection:
Clinical evidence of invasive disease with no other apparent cause and with non-confirmatory laboratory evidence:
Sputum and bronchial lavages are not considered sterile specimens.
Demonstration of S. pneumoniae DNA or antigen does not permit determination of serotype. Serotyping is carried out in a reference laboratory and is important for monitoring changes in disease epidemiology, including the impact of vaccination programs and serotype replacement.
Clinical illness associated with invasive disease manifests itself mainly as pneumonia with bacteremia, bacteremia without a known site of infection, and meningitis. Pneumonia without bacteremia is not notifiable.
6.1 ICD-10 code(s)
A40.3 Septicaemia due to S. pneumoniae
B95.3 pneumoniae as the cause of diseases classified elsewhere, e.g.:
I30.1 Infective pericarditis
K65.0 Acute peritonitis
M00.8 Arthritis and polyarthritis due to other specified bacterial agents
O85 Puerperal sepsis
P23.6 Congenital pneumonia due to other bacterial agents
G00.1 Meningitis due to S. pneumoniae
J13 Pneumonia due to S. pneumoniae
M00.1 Pneumococcal arthritis and polyarthritis
038.2 Septicaemia due to S. pneumoniae
041.2 S. S. pneumoniae of unspecified site and as the cause of diseases classified elsewhere, e.g.:
420.9 Infective pericarditis
711.0 Pyogenic arthritis
567.1 Pneumococcal peritonitis
320.1 Meningitis due to S. pneumoniae
481 Pneumonia due to S. pneumoniae
711.0 Pneumococcal arthritis and polyarthritis
Probable case definitions are provided as guidelines to assist with case finding and public health management, and are not for national notification purposes.
Laboratory Centre for Disease Control. Preventing pneumococcal disease: a Canadian consensus conference. CCDR 1999;25:25-35.
Previous case definitions
Case definitions for diseases under national surveillance. CCDR 2000;26(S3).
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