National case definition: Invasive Pneumococcal Disease
Invasive pneumococcal disease
Date of last revision/review: May 2008
Only confirmed cases of disease should be notified.
Type of surveillance
Routine case-by-case notification to the federal level
Enhanced case-by-case notification to International Circumpolar Surveillance in participating Northern regions
Enhanced active case-by-case notification by paediatric tertiary care hospitals involved in the Immunization Monitoring Program, Active (IMPACT)
- Clinical evidence of invasive disease (see Clinical evidence section) with laboratory confirmation of infection:
- isolation of Streptococcus pneumoniae from a normally sterile site (excluding the middle ear and pleural cavity)
- demonstration of S. pneumoniae DNA from a normally sterile site (excluding the middle ear and pleural cavity)
- Clinical evidence of invasive disease with no other apparent cause and with non-confirmatory laboratory evidence:
- demonstration of S. pneumoniae antigen from a normally sterile site (excluding the middle ear and pleural cavity)
Sputum and bronchial lavages are not considered sterile specimens.
Demonstration of S. pneumoniae DNA or antigen does not permit determination of serotype. Serotyping is carried out in a reference laboratory and is important for monitoring changes in disease epidemiology, including the impact of vaccination programs and serotype replacement.
Clinical illness associated with invasive disease manifests itself mainly as pneumonia with bacteremia, bacteremia without a known site of infection, and meningitis. Pneumonia without bacteremia is not notifiable.
- 6.1 ICD-10 code(s)
- A40.3 Septicaemia due to S. pneumoniae
- B95.3 pneumoniae as the cause of diseases classified elsewhere, e.g.:
- I30.1 Infective pericarditis
- K65.0 Acute peritonitis
- M00.8 Arthritis and polyarthritis due to other specified bacterial agents
- O85 Puerperal sepsis
- P23.6 Congenital pneumonia due to other bacterial agents
- G00.1 Meningitis due to S. pneumoniae
- J13 Pneumonia due to S. pneumoniae
- M00.1 Pneumococcal arthritis and polyarthritis
- ICD-9/ICD-9CM code(s)
- 038.2 Septicaemia due to S. pneumoniae
- 041.2 S. S. pneumoniae of unspecified site and as the cause of diseases classified elsewhere, e.g.:
- 420.9 Infective pericarditis
- 711.0 Pyogenic arthritis
- 567.1 Pneumococcal peritonitis
- 320.1 Meningitis due to S. pneumoniae
- 481 Pneumonia due to S. pneumoniae
- 711.0 Pneumococcal arthritis and polyarthritis
Probable case definitions are provided as guidelines to assist with case finding and public health management, and are not for national notification purposes.
Laboratory Centre for Disease Control. Preventing pneumococcal disease: a Canadian consensus conference. CCDR 1999;25:25-35.
Previous case definitions
Case definitions for diseases under national surveillance. CCDR 2000;26(S3).
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