Dosage of intramuscular EPINEPHrine 1:1000 (1 mg/mL) solution, by age or weight

Weight is the preferred basis for dosage but if unknown, use age as a guide.

Age
Use weight if available
Weight (kg) EPINEPHrine dose
(1 mg/mL) ampoule/vial
EPINEPHrine
autoinjector dose
Use only if measured dose by weight is unavailable
mg
or
mg/kg/dose
Volume
1 mg/mL
(mL)
Birth to less
5 kg
Less than 5 kg 0.01
mg/kg/dose
or
0.1 mg
0.01
mL/kg/dose
or
0.1 mL
N/A
Greater than 5 kg and less than 2 years 5 - 10 0.1 mg 0.1 mL 0.15 mg
2 to less than 4 years 11 - 15 0.15 mg 0.15 mL
4 to less than 7 years 16 - 20 0.2 mg 0.2 mL
21 - 25 0.25 mg 0.25 mL 0.3 mg
7 to less than 10 years 26 - 30 0.3 mg 0.3 mL
31 - 35 0.35 mg 0.35 mL
10 to 12 years 36 - 40 0.4 mg 0.4 mL
41 - 45 0.45 mg 0.45 mL
Older than 12 years 46 and above 0.5 mg 0.5 mL 0.5 mg

Reference

Public Health Agency of Canada. Anaphylaxis and other acute reactions following immunization: Canadian Immunization Guide: Part 2 – Vaccine Safety. Ottawa (ON): PHAC; 2020. Table 4 Dosage of intramuscular EPINEPHrine 1:1000 (1 mg/mL) solution, by age or weight.

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