Sulfuric acid, diethyl ester (Diethyl sulfate)

CAS Registry Number 64-67-5

What is it?

  • Sulfuric acid, diethyl ester, also known as diethyl sulfate, is an industrial chemical.

How is it used?

  • In Canada, Diethyl sulfate is mainly used to make other chemicals which are then used in the manufacturing of softeners used to increase absorbency of tissue paper.
  • Diethyl sulphate may also be used to make products used in the manufacturing of a variety of other substances and products, including dyes, fragrances, and quaternary ammonium salts used as surfactants or flocculants in water treatment.
  • It may also be used as an ethylating agent in the manufacture of commercial products such as sanitizers and organoclays.
  • Based on the most recent data available, diethyl sulfate is not manufactured in Canada, but is imported into Canada.

Why did the Government of Canada assess it?

  • Diethyl sulfate was identified as a potential concern to human health based on its classification by international organizations as a substance which was found to cause cancer and genetic damage in some studies with laboratory animals, and based on what was believed to be a moderate potential for exposure to Canadians.

How are Canadians exposed to it?

  • Exposure to diethyl sulfate is expected to be very low and occur predominantly through inhalation of air.

What is the Government of Canada doing?

  • The Government of Canada has conducted a science-based evaluation of diethyl sulfate, called a screening assessment.
  • The Government of Canada has concluded that diethyl sulfate is considered to be harmful to human health at current levels of exposure.
  • Canadians' exposure is very low and the Government is taking action so that exposure remains low.
  • The Government of Canada will investigate the utility of implementing a future use notification. This would require that any proposed new uses of diethyl sulfate be subject to further assessment before considering whether to allow such activities.
  • It is also being proposed that diethyl sulfate be added to the Cosmetic Ingredient "Hotlist" which will prevent its future use in cosmetics.
  • The final screening assessment and the proposed risk management approach were published on August 1, 2009. The proposed risk management approach will be followed by a 60-day comment period, ending September 30, 2009.

What should Canadians do?

  • The health risks associated with a chemical depend on the hazard (its potential to cause health effects) and the dose (the amount of chemical to which you are exposed).
  • Because exposure to diethyl sulfate is very low, the Government of Canada is not currently recommending specific actions to reduce Canadians' exposure.
Report a problem or mistake on this page
Please select all that apply:

Thank you for your help!

You will not receive a reply. For enquiries, contact us.

Date modified: