2-Naphthalenesulfonic acid, 7-[[4,6-bis[[3-(diethylamino)propyl]amino]-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[[4-(phenylazo)phenyl]azo]-, monoacetate (salt) (NDTHPM)

CAS Registry Number 71032-95-6

What is it?

• 2-Naphthalenesulfonic acid, 7-[[4,6-bis[[3-(diethylamino)propyl]amino]-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[[4-(phenylazo)phenyl]azo]-, monoacetate (salt), also known as, NDTHPM, is an industrial chemical.

How is it used?

• NDTHPM is a synthetic dye primarily used as a paper colorant.
• This substance is not manufactured in Canada but is imported into Canada.

Why did the Government of Canada assess it?

• Prior to assessment, NDTHPM was identified as a potential concern to the environment based on information regarding possible persistence, accumulation in organisms and potential to cause harm to organisms.
• NDTHPM was not considered to be a high priority for assessment of potential risks to human health; however, potential health effects were also evaluated in this screening assessment.

How are Canadians exposed to it?

• The general population of Canada may be exposed to low levels of NDTHPM from environmental media (air, soil, water); however, this exposure is expected to be low.
• Exposure to NDTHPM from consumer products (e.g., non-food paper products containing NDTHPM dye) may occur for incidental events such as ingestion by toddlers.

How is it released to the environment?

• NDTHPM may be released to the environment via wastewater treatment systems and waste disposal processes as a result of industrial and consumer use of products containing this substance.

What are the results of the assessment?

• The Government of Canada has conducted a science-based evaluation of NDTHPM called a screening assessment.
• Screening assessments address potential for harm to the general population (not including workplace exposures) and the environment.
• Results of the final screening assessment indicate that although NDTHPM has the potential to remain in the environment for a long time, it is not expected to accumulate in organisms.
• Furthermore, the quantity of NDTHPM that may be released to the environment is below the level expected to cause harm to organisms.
• The Government of Canada has therefore concluded that NDTHPM is not entering the environment in a quantity or under conditions that constitute a danger to the environment.
• The Government of Canada has also concluded that NDTHPM is not considered to be harmful to the health of the general population at current levels of exposure.

What is the Government of Canada doing?

• Exposure of the general population of Canada to NDTHPM is expected to be low and the Government of Canada is proposing additional action so that exposure remains low.
• The application of the Significant New Activity (SNAc) provisions to this substance will be recommended. This would require that any proposed new manufacture, import or use be subject to further assessment, and would determine if the new activity requires further risk management consideration.
• The final screening assessment and the proposed risk management approach documents were published on September 18, 2010.

What can Canadians do?

• The health risks associated with a chemical depend on the hazard (its potential to cause health effects) and the dose (the amount of chemical to which you are exposed). However, exposure of the general population to NDTHPM is expected to be low.
• As a general precaution, Canadians are reminded when using any product to carefully follow any safety warnings and directions.
• Canadians who handle NDTHPM in the workplace should consult with their occupational health and safety representative about safe handling practices, applicable laws and requirements under the Workplace Hazardous Materials Information System.