DTPMP - information sheet

Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1- ethanediylnitrilobis(methylene)]]tetrakis- (DTPMP)
CAS Registry Number 15827-60-8

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Overview

  • The Government of Canada conducted a science-based evaluation, called a screening assessment, of DTPMP to address the potential for harm to Canadians and to the environment.
  • Under the Canadian Environmental Protection Act, 1999 (CEPA 1999), the risk posed by a substance is determined by considering both its hazardous properties (its potential to cause adverse human health or ecological effects) and the amount of exposure there is to people and the environment. A substance may have hazardous properties; however, the risk to human health or to the environment may be low depending upon the level of exposure.
  • The ecological hazard and exposure potentials of this substance were classified using the Ecological Risk Classification of Organic Substances Approach.
  • As a result of this screening assessment, DTPMP is proposed as not harmful to human health or the environment.

About this substance

  • This screening assessment focused on the substance phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]] tetrakis-, also referred to as DTPMP. It was assessed under the Chemicals Management Plan (CMP).
  • DTPMP does not occur naturally in the environment.
  • According to information gathered by the Government of Canada, this substance is man-made. In Canada DTPMP is used in commercial applications, including water treatment, laundry and dishwashing, paints and coatings, oil and gas extraction, construction and building materials, paper products, ink, toner and colourants, photographic supplies, and in a variety of care products (that is, fabric, cleaning and furnishing care, personal care, apparel and footwear care, and air care).
  • This substance is also found in products available to consumers, including permanent hair dye products, and as a non-medicinal ingredient in lubricating eye drops.

Human and ecological exposures

  • Canadians may be exposed to this substance from the use of products available to consumers, such as permanent hair dye products and lubricating eye drops.
  • Exposure to Canadians to DTPMP from industrial releases into the environment (for example, water) is expected to be minimal.
  • According to information considered under the Ecological Risk Classification of organic substances approach, DTPMP was identified as having a moderate ecological exposure potential based on moderate reported quantities and persistence (ability to stay in the environment for a long time).

Key health and ecological effects (hazard)

  • DTPMP has been reviewed by the Organisation for Economic Cooperation and Development (OECD) Cooperative Chemicals Assessment Programme. The Screening Information Data Set (SIDS) and SIDS Initial Assessment Report (SIAR) are available. This review was used to inform the health effects characterization in this screening assessment. The important or “critical” effect for the characterization of risk to human health for DTPMP was disruption of the body’s ability to keep stable levels of iron and calcium.
  • According to information considered under the Ecological Risk Classification of organic substances approach, DTPMP was identified as having a low ecological hazard potential.

Risk assessment outcomes

  • Based upon a comparison of levels to which Canadians may be exposed to DTPMP, and the levels associated with health effects, the risk to human health for this substance is considered to be low.
  • Based on the outcome of the Ecological Risk Classification of Organic Substances Approach, DTPMP is considered unlikely to cause ecological harm.
  • The Government of Canada published the Draft Screening Assessment for DTPMP on March 16, 2019. This publication has a 60-day public comment period ending on May 15, 2019.

Proposed screening assessment conclusions

  • As a result of this assessment, the Government is proposing that DTPMP is not harmful to human health at current levels of exposure.
  • The Government is also proposing that DTPMP is not entering the environment at levels that are harmful to the environment.

Related Information

  • DTPMP may be found in products available to consumers. Canadians should follow any safety warnings and directions on product labels and dispose of products responsibly.
  • Visit Healthy Home for more information on chemical safety in and around the home.
  • Canadians who may be exposed to DTPMP in the workplace can consult with their employer and an occupational health and safety (OHS) representative about safe handling practices, applicable laws, and requirements under OHS legislation and the Workplace Hazardous Materials Information System (WHMIS).
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