Proposed re-evaluation decision PRVD2025-01, Streptomyces lydicus Strain WYEC 108 and its associated end-use products

Pest Management Regulatory Agency
30 January 2025
ISSN: 1925-0967 (PDF version)
Catalogue number: H113-27/2025-1E-PDF (PDF version)

Summary

Table of contents

• Proposed re-evaluation decision for Streptomyces lydicus strain WYEC 108 and associated end use products
• Proposed re-evaluation decision for Streptomyces lydicus strain WYEC 108
• Key risk-reduction measures
• Next steps
• Other information
• Additional scientific information

Proposed re-evaluation decision for Streptomyces lydicus strain WYEC 108 and associated end use products

Under the authority of the Pest Control Products Act, all registered pesticides must be re-evaluated by Health Canada's Pest Management Regulatory Agency (PMRA) to ensure that they continue to meet current health and environmental standards and continue to have value. The re-evaluation considers data and information from pesticide manufacturers, published scientific reports and other regulatory agencies. Health Canada applies internationally accepted risk assessment methods as well as current risk management approaches and policies.

This document (Proposed Re-evaluation Decision PRVD2025-01, Streptomyces lydicus Strain WYEC 108 and Its Associated End-use Products) presents the proposed re-evaluation decision for Streptomyces lydicus strain WYEC 108, including the proposed amendments (risk mitigation measures) to protect human health and the environment, as well as the Science evaluation on which the proposed decision is based.

Streptomyces lydicus strain WYEC 108 is a microbial pest control agent (MPCA) registered as a preventative fungicide to suppress fungal diseases in agricultural field- and/or greenhouse-grown food crops and flowering ornamentals, including use as a seed treatment in select greenhouse-grown food crops. Currently registered products containing Streptomyces lydicus strain WYEC 108 can be found in the Pesticide Product Information Database and in Appendix I of the full version of PRVD2025-01.

Streptomyces lydicus strain WYEC 108 is a naturally occurring bacteria. Streptomyces lydicus strain WYEC 108 works by invading and growing within the fungal pathogens, where it releases enzymes that break down the cell wall of fungi. It also readily grows on the tip of plant roots, which protects the plant's roots from plant pathogens by competing with and displacing fungi that may cause disease and by excreting metabolites that target disease fungi.

Streptomyces lydicus strain WYEC 108 has a multiple-site mode of action and has value in providing a pest management solution. Based on the current use pattern, the potential risks to human health (dietary, occupational and bystander) and the environment (aquatic and terrestrial organisms) are considered to be acceptable when products containing Streptomyces lydicus strain WYEC 108 are used according to the current label directions. As a result of re-evaluation, no additional mitigation measures are proposed, however, updates to standard label statements as per current labelling standards are proposed. Refer to Appendix II of PRVD2025-01 for details.

The registrant no longer supports uses of Streptomyces lydicus strain WYEC 108 on cannabis and industrial hemp. Therefore, these uses will not be re-evaluated, and will be removed from the labels.

Proposed re-evaluation decision for Streptomyces lydicus strain WYEC 108

Under the authority of the Pest Control Products Act, and based on available scientific information in accordance with subsection 16(6) of the Pest Control Products Act, Health Canada is proposing for public consultation, pursuant to section 28 of the Pest Control Products Act, the continued registration of Streptomyces lydicus strain WYEC 108 and associated end-use products registered for sale and use in Canada under section 21 of the Pest Control Products Act.

This proposed re-evaluation decision is a consultation document and is subject to a 90-day public consultation period.^{Footnote 1} Comments on the proposed decision can be submitted to the PMRA through PMRA Publications, or the Public Engagement Portal (Public Engagement Forms - Consultation Comment). All products containing Streptomyces lydicus strain WYEC 108 that are registered in Canada are subject to this proposed re-evaluation decision.

Refer to Appendix I of PRVD2025-01 for details on specific products impacted by this proposed decision.

Key risk-reduction measures

Human health

• Label improvements to meet current standards: update personal protective equipment for clarity and to add protective eyewear (goggles), and addition of standard spray drift.

Environment

• Label improvements to meet current standards: update environmental precautions and disposal.

Next steps

Upon publication of this proposed re-evaluation decision, the public, including the registrants and stakeholders are encouraged to submit comments during the 90-day public consultation period.

Before making a re-evaluation decision on Streptomyces lydicus strain WYEC 108 under section 21 of the Pest Control Products Act, written comments received during the consultation period will be taken into consideration, and a science-based approach will be applied in making a final decision on Streptomyces lydicus strain WYEC 108. In accordance with subsection 28(5) of the Pest Control Products Act, Health Canada will then publish a final re-evaluation decision document, which will include the decision^{Footnote 2}, the reasons for it, a summary of the comments received on the proposed re-evaluation decision during the consultation period, and Health Canada's response to these comments.

Other information

The relevant confidential test data on which the proposed decision is based are available for public inspection, upon application, in PMRA's Reading Room. For more information or if you have questions, please contact the PMRA's Pest Management Information Service.

Additional scientific information

No additional scientific data are being requested at this time.