Page 9: Human Antimicrobial Use Report – 2014 - Appendix C – Additional hospital purchasing data

Appendix C – Additional hospital purchasing data

Table C.1: Raw kilograms of active ingredient purchased by hospitals 2004-2014
Antimicrobial	Rank	DIRI	2004	2005	2006	2007	2008	2009	2010	2011	2012	2013	2014
Table c.1 - Footnote * Ranked from greatest to least mass of active ingredient purchased in 2014. Return to first Table c.1 - Footnote * referrer Antimicrobials were removed from this table if they represented <0.5% of mass of active ingredient purchased in 2014. These are: amikacin, bacitracin, cefaclor, cefadroxil, cefepime, cefixime, cefotaxime, cefotetan, cefprozil, ceftazidime, ceftizoxime, ceftobiprole, chloramphenicol, clarithromycin, colistin, daptomycin, demeclocycline, doxycycline, ertapenem, erythromycin, doripenem, fosfomycin, fusidic acid, gatifloxacin, gemifloxacin, gentamicin, imipenem, imipenem and cilastatin, lincomycin, linezolid, methenamine hippurate, methenamine mandelate, metronidazole, minocycline, nalidixic acid, netilmicin, nitrofurantoin, norfloxacin, ofloxacin, penicillin v, piperacillin, pivampicillin, polymyxin b, quinupristin/dalfopristin, spiramycin, streptomycin, sulfadiazine and trimethoprim, sulfonamides, combinations with other antibacterials (excl. trimethoprim), telithromycin, tetracycline, ticarcillin and enzyme inhibitor, tigecycline, tobramycin, and trimethoprim.
Amoxicillin	8	-	1066	1174	1013	971	973	1045	1100	1160	1197	1263	1296
Amoxicillin and enzyme inhibitor	10	-	459	550	629	489	507	587	591	723	820	831	1066
Ampicillin	11	-	1318	2051	2211	1358	1118	1056	989	983	953	948	911
Azithromycin	14	-	213	227	193	239	261	296	325	385	460	489	455
Cefazolin	3	-	4128	4152	3896	4429	4570	4865	4590	4576	4687	3917	3405
Cefoxitin	2	-	12594	10113	9757	9705	8561	10350	7870	7797	6258	4614	5331
Ceftriaxone	4	-	723	789	844	999	1216	1500	1528	1907	2111	2406	2503
Cefuroxime	17	-	617	555	386	347	299	297	360	378	337	230	246
Cephalexin	9	-	1239	1362	1664	1095	1084	1097	1004	1102	1160	1213	1178
Ciprofloxacin	5	-	1703	1539	1632	1644	1637	1617	1434	1453	1507	1711	1541
Clindamycin	12	-	516	548	866	919	908	920	857	882	868	1414	858
Cloxacillin	7	-	1455	1413	1336	1312	1257	1397	1243	1329	1329	1292	1337
Levofloxacin	16	-	409	365	316	313	318	349	303	337	320	307	286
Meropenem	13	^{Table c.1 - Footnote *}	261	227	356	400	458	548	539	558	546	591	589
Moxifloxacin	18	^{Table c.1 - Footnote *}	175	261	352	374	375	378	331	330	307	258	239
Penicillin G	19	-	110	109	100	108	98	102	320	375	379	204	231
Piperacillin and enzyme inhibitor	1	^{Table c.1 - Footnote *}	3043	4047	4637	5742	6325	8862	9234	11653	12304	12696	13234
Sulfamethoxazole and trimethoprim	6	-	1627	1670	1720	1602	1559	1612	1496	1526	1522	1509	1421
Vancomycin	15	-	265	289	210	190	203	251	382	462	471	346	353

Table C.2: Dollars spent (000's) on antimicrobials purchased by hospitals 2004-2014
Antimicrobial	Rank	DIRI	2004	2005	2006	2007	2008	2009	2010	2011	2012	2013	2014
Table c.2 - Footnote * Ranked from greatest to least dollars spent in 2014. Return to first Table c.2 - Footnote * referrer Antimicrobials were removed from this table if they represented <0.5% of dollars spent in 2014. These are: amoxicillin, cefaclor, cefadroxil, cefepime, cefixime, cefotetan, cefoxitin, cefprozil, ceftizoxime, ceftobiprole, chloramphenicol, clarithromycin, demeclocycline, doripenem, doxycycline, fidaxomicin, fosfomycin, gatifloxacin, gemifloxacin, imipenem, lincomycin, methenamine hippurate, methenamine mandelate, metronidazole, minocycline, nalidixic acid, netilmicin, nitrofurantoin, norfloxacin, ofloxacin, fusidic acid, piperacillin, pivampicillin, polymyxin b, quinupristin/dalfopristin, spiramycin, streptomycin, sulfadiazine and trimethoprim, sulfonamides, combinations with other antibacterials (excl. trimethoprim), telithromycin, tetracycline, ticarcillin and enzyme inhibitor, trimethoprim.
Amikacin	26	^{Table c.2 - Footnote *}	113	403	562	519	513	652	585	487	775	696	703
Amoxicillin and enzyme inhibitor	28	-	616	646	662	527	533	645	644	650	628	586	641
Ampicillin	8	-	1060	1074	1079	1209	1019	1168	1248	1541	2963	4272	4127
Azithromycin	13	-	6301	6601	4703	4328	4552	5059	2593	2276	2372	2198	2167
Bacitracin	20	-	694	538	762	897	922	629	750	971	1003	936	988
Cefazolin	9	-	4979	5093	4703	5763	4982	5173	7188	6004	4551	3198	3984
Cefotaxime	24	-	4782	4947	5372	5241	3508	3381	1962	1739	1417	926	870
Ceftazidime	19	-	3123	2283	1466	1276	1226	1326	1229	1136	1320	1326	1068
Ceftriaxone	11	-	24246	26209	27410	19275	7661	5953	3125	3494	4926	3346	3548
Cefuroxime	27	-	1919	1793	1215	1104	868	888	1034	976	843	724	702
Cephalexin	30	-	480	518	632	459	460	447	449	519	598	596	555
Ciprofloxacin	15	-	26208	24960	26658	21200	8955	2973	2442	2103	1691	1972	1611
Clindamycin	7	-	1789	1799	3411	3684	3715	3859	3428	3543	4195	4058	4128
Cloxacillin	14	-	1325	1419	1530	1785	1785	2579	2549	2948	2465	1877	1992
Colistin	22	^{Table c.2 - Footnote *}	533	452	648	695	705	544	821	810	822	1089	893
Daptomycin	4	^{Table c.2 - Footnote *}	-	-	-	-	67	856	1567	2759	4509	6813	8559
Ertapenem	3	^{Table c.2 - Footnote *}	429	1036	1723	2189	3254	4374	5165	7269	8427	9369	9826
Erythromycin	29	-	562	470	567	589	607	452	364	626	653	607	627
Gentamicin	21	^{Table c.2 - Footnote *}	566	926	2006	2846	2718	2751	2693	2491	2768	2963	969
Imipenem and cilastatin	18	^{Table c.2 - Footnote *}	-	-	-	-	-	-	5800	1941	2527	1522	1192
Levofloxacin	25	-	8389	5856	4306	4386	4757	5005	3831	4224	2383	879	738
Linezolid	5	^{Table c.2 - Footnote *}	2045	3294	3624	4536	5348	5993	5236	5562	6596	6184	5377
Meropenem	2	^{Table c.2 - Footnote *}	12450	10961	17172	19476	22319	26916	26500	27585	19256	13776	14236
Moxifloxacin	6	^{Table c.2 - Footnote *}	3610	6303	8746	9946	10496	9971	6939	6972	6458	5522	5064
Penicillin G	17	-	621	617	597	643	661	1521	773	950	1401	1338	1337
Piperacillin and enzyme inhibitor	1	^{Table c.2 - Footnote *}	14768	19247	22242	28029	23275	16722	14327	17511	17608	14906	15499
Sulfamethoxazole and trimethoprim	23	-	1032	1028	1095	1055	1088	1206	1048	1087	1304	1385	886
Tigecycline	16	^{Table c.2 - Footnote *}	-	-	-	384	970	1924	1921	1533	1542	1334	1373
Tobramycin	12	^{Table c.2 - Footnote *}	285	524	1675	1844	1847	1979	2002	1879	2046	1641	2619
Vancomycin	10	-	5629	5889	4653	5068	4276	5215	4445	4532	4254	3519	3747
TOTAL	-	-	148589	155238	166311	165937	138234	134562	119363	122013	117352	104241	104045

Table C.3: Dollars spent (000's) on antimicrobials purchased by hospitals in Canadian provinces, 2014
Antimicrobial	Rank	DIRI	BC	AB	SK	MB	ON	QC	NB	NS	PEI & NL
Table c.3 - Footnote * Ranked from greatest to least dollars spent in 2014. Return to first Table c.3 - Footnote * referrer Antimicrobials were removed from this table if they represented <0.5% of dollars spent in 2014. These are: amoxicillin, cefaclor, cefadroxil, cefepime, cefixime, cefotetan, cefprozil, ceftizoxime, ceftobiprole, chloramphenicol, clarithromycin, demeclocycline, doripenem, doxycycline, fidaxomicin, fosfomycin, fusidic acid, gatifloxacin, imipenem, lincomycin, methenamine hippurate, methenamine mandelate, metronidazole, minocycline, nalidixic acid, netilmicin, nitrofurantoin, norfloxacin, ofloxacin, penicillin v, gemifloxacin, pivampicillin, polymyxin b, quinupristin/dalfopristin, spiramycin, streptomycin, sulfadiazine and trimethoprim, sulfonamides, combinations with other antibacterials (excl. trimethoprim), telithromycin, tetracycline, ticarcillin and enzyme inhibitor, and trimethoprim.
Amikacin	26	^{Table c.3 - Footnote *}	139	61	9	16	324	125	5	12	12
Amoxicillin and enzyme inhibitor	28	-	88	77	18	57	135	217	16	14	19
Ampicillin	8	-	551	462	103	140	1668	926	95	109	74
Azithromycin	13	-	456	287	131	122	658	365	35	61	53
Bacitracin	20	-	117	152	51	16	460	109	19	28	37
Cefazolin	9	-	88	374	102	207	1661	982	267	153	149
Cefotaxime	24	-	138	106	88	22	150	270	24	41	31
Ceftazidime	19	-	20	36	7	25	247	483	157	64	29
Ceftriaxone	11	-	563	531	178	317	1292	376	67	96	128
Cefuroxime	27	-	78	52	15	25	121	288	61	42	20
Cephalexin	30	-	106	55	16	82	194	60	15	12	15
Ciprofloxacin	15	-	93	66	16	32	831	393	89	62	30
Clindamycin	7	-	643	564	195	297	1225	793	154	102	156
Cloxacillin	14	-	484	167	65	103	639	363	81	34	55
Colistin	22	^{Table c.3 - Footnote *}	100	39	9	9	474	190	6	31	35
Daptomycin	4	^{Table c.3 - Footnote *}	4214	937	168	185	1313	1332	82	150	179
Ertapenem	3	^{Table c.3 - Footnote *}	2839	1215	291	366	1489	3140	52	136	297
Erythromycin	29	-	118	65	36	33	130	167	17	27	33
Gentamicin	21	^{Table c.3 - Footnote *}	127	135	30	38	242	347	15	27	8
Imipenem and cilastatin	18	^{Table c.3 - Footnote *}	419	65	1	23	131	361	34	143	16
Levofloxacin	25	-	39	192	8	54	311	85	33	14	3
Linezolid	5	^{Table c.3 - Footnote *}	1220	920	161	276	1065	1547	62	45	79
Meropenem	2	^{Table c.3 - Footnote *}	1901	1139	450	497	4093	5571	158	170	257
Moxifloxacin	6	^{Table c.3 - Footnote *}	768	129	283	130	1693	1304	156	206	395
Penicillin G	17	-	248	130	20	6	372	499	34	18	11
Piperacillin and enzyme inhibitor	1	^{Table c.3 - Footnote *}	2264	1426	547	519	4526	5241	404	350	222
Sulfamethoxazole and trimethoprim	23	-	131	94	32	60	262	231	16	50	11
Tigecycline	16	^{Table c.3 - Footnote *}	152	157	89	10	268	648	18	21	12
Tobramycin	12	^{Table c.3 - Footnote *}	135	122	48	105	1200	839	36	75	59
Vancomycin	10	-	414	168	1	68	160	2503	104	327	3
TOTAL	-	-	19246	10366	3305	4092	28219	31041	2427	2820	2528

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Date modified:: 2015-11-17