Human emerging respiratory pathogens bulletin: Issue 42, June 2020
Organization: Public Health Agency of Canada
Date published: 2020-07-14
Monthly situational analysis of emerging respiratory diseases affecting humans (data to June 30, 2020)
In this bulletin
- COVID-2019 update
- Avian influenza updates
- Swine influenza updates
- Middle East respiratory syndrome coronavirus (MERS-CoV) update
|Novel influenzaTable 1 Footnote 1||Cumulative Case CountTable 1 Footnote 2||Deaths||Case Fatality Rate %Table 1 Footnote 3|
|MERS-CoVTable 1 Footnote 1||Cumulative Case CountTable 1 Footnote 2||Deaths||Case Fatality Rate %Table 1 Footnote 3|
|Global Case Count||2,552||871||34%|
On December 31, 2019, cases of a pneumonia of unknown etiology were reported in Wuhan, China, which have since been determined to be due to a novel coronavirus (COVID-2019). On January 30, 2020, the World Health Organization (WHO) declared the outbreak a Public Health Emergency of International Concern (PHEIC).As of June 30, 2020, 104,204 cases of COVID-2019 have been reported in Canada. The highest number of cases were reported from Ontario and Quebec (represent 87% of the national cases). The Public Health Agency of Canada is monitoring the situation closely.
Avian influenza updates
Avian influenza A(H7N9)No new H7N9 cases were reported to the WHO in June 2020. The last case was globally reported in April 2019. Two travel-related cases were reported in Canada in January 2015. A total of 1568 human cases of avian influenza A(H7N9), including at least 615 deaths, have been reported globally since 2013 (Figure 1).
Figure 1. Temporal distribution of human infection with avian influenza A(H7N9), globally, by month and year, January 1, 2013 to June 30, 2020 (n=1568).
Note: Graph was prepared by the Centre for Immunization and Respiratory Infectious Diseases (CIRID) using data from the latest WHO Monthly Influenza at the Human-Animal Interface Risk Assessment. This graph reflects data available through these risk assessments as of June 30, 2020.
Figure 1 - Text Equivalent
The temporal distribution of avian influenza A(H7N9), globally, January 1st, 2013 – June 30, 2020, has been displayed in Figure 1. The highest number of reports occurred in 2017, with a peak in January. Three cases were reported in 2018 and one case was reported in 2019.
Avian influenza A(H5N1)
No new H5N1 cases were reported to WHO in June 2020. The most recent case was reported in March 25, 2019 in Nepal. A total of 879 cases including 461 deaths have been reported globally since 1997. One fatal travel-related case of H5N1 was reported in Canada in January 2014.
Avian influenza A(H5N6)
No new cases of H5N6 were reported to the WHO in June 2020. The most recent case of H5N6 was reported in China in August 2019. There have been a total of 24 cases, including 7 deaths, reported globally since 2014, all in China.
Swine influenza updates
Swine origin influenza A(H1N2)v
On June 22, 2020, Brazil reported a human infection with A(H1N2)v. The case was a 22 year old female who worked in a slaughterhouse and developed influenza-like illness on April 13, 2020. She obtained medical care on April 16, at which point a respiratory specimen was collected for testing. Routine real-time RT-PCR identified the specimen as influenza A and on June 22, 2020, genetic sequencing results characterized the virus as A(H1N2)v. Prior to this case, Brazil had only reported one A(H1N2)v case in 2015, resulting in a total of two cases reported from Brazil thus far.
Swine origin influenza A(H1N1)v
A study published on June 29, 2020 identified a recently emerged genotype 4 Eurasian avian-like H1N1 (G4 EA H1N1) virus that has been predominant in swine populations since 2016 in at least 10 Chinese provinces. Swine workers have been found seropositive for the virus, indicating possible swine to human transmission. There have been two cases in humans, in 2016 and 2019, in a 46 year old and a 9 year old and there is no evidence of ongoing transmission from these cases.Another influenza A(H1N1) infection was detected in a 2 year old case from Hesse, Germany in June 2020. This case presented with influenza-like illness on June 9, 2020 after contact with pigs during a farm visit. Whole genome sequencing results identified the virus as a Eurasian avian-like swine A(H1N1) virus. This virus is similar to the 1C.2.2 clade viruses that circulate in swine in Europe and differs from the 1C.2.3 clade viruses that circulate in Chinese swine according to the previously referenced study. To date, reported H1N1v infections have been associated with mild illness.
Middle East respiratory syndrome coronavirus (MERS-CoV) update
In June 2020, no new cases of MERS-CoV were reported. A total of 2552 laboratory-confirmed cases of MERS-CoV, including 871 deaths, have been reported globally since 2012 by the WHO. No cases have been reported in Canada.
Figure 3. Spatial distribution of human cases of MERS-CoV reported in June 2020 (n=397).
Note: Graph was prepared by the Centre for Immunization and Respiratory Infectious Diseases (CIRID) using data from the WHO Disease Outbreak News and Saudi Arabia's Ministry of Health. This graph reflects data available as of June 30, 2020.
Figure 3 - Text Equivalent
The temporal distribution of MERS-CoV, globally, January 1st, 2018– June 30, 2020, has been displayed in Figure 3.
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