Participate in the risk assessment process for the EntoEngine fly
Current status: Open
From December 30, 2022 to January 28, 2023, the New Substances program is seeking scientific information and test data that could inform the risk assessment process for the EntoEngine fly as part of the Voluntary Public Engagement Initiative.
The New Substances program, jointly administered by Environment and Climate Change Canada and Health Canada, is currently evaluating the EntoEngine fly, notified by Future Fields on November 18, 2022.
This genetically modified Drosophila melanogaster, commonly referred to as the “fruit fly”, acts as a living insect bioreactor, capable of expressing recombinant proteins on demand. The line subject to this notification expresses a growth factor protein that is intended for use as a component of cell culture medium for research use.
The EntoEngine fly line has been genetically engineered to express a growth factor isolated from cows. Growth factors are the unique cell signaling molecules that play important roles in cell proliferation and development. The gene sequence poses no known risks to either humans or animals. Expression of the gene encoding the growth factor is under the control of a gene expression regulator isolated from yeast. A chromosome stabilizer increases the stability of the line.
Join in: How to participate
All interested parties are invited to share scientific information and test data related to potential risks to the environment or human health from the EntoEngine fly.
Send your comments to the address in the Contact us section below.
Submit your comments by email: firstname.lastname@example.org
Review our privacy statement for this consultation.
Who is the focus of this consultation
We would like to hear from:
- Indigenous peoples
- Provincial, territorial and local governments
- Industry stakeholders and association members
- Non-governmental organizations
- General public
Key questions for discussion
Canadians are invited to provide scientific information and test data that could inform the risk assessment process.
Substances Management Information Line
Science and Technology Branch
Environment and Climate Change Canada
Place Vincent Massey, 351 St. Joseph Blvd
Gatineau QC K1A 0H3
Telephone: 1-800-567-1999 (Toll Free in Canada) or 1-819-938-3232 (Outside of Canada)
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