Participate in the risk assessment process for the EntoEngine fly

From: Environment and Climate Change Canada

Current status: Open

From December 30, 2022 to January 28, 2023, the New Substances program is seeking scientific information and test data that could inform the risk assessment process for the EntoEngine fly as part of the Voluntary Public Engagement Initiative.

Background

The New Substances program, jointly administered by Environment and Climate Change Canada and Health Canada, is currently evaluating the EntoEngine fly, notified by Future Fields on November 18, 2022.

This genetically modified Drosophila melanogaster, commonly referred to as the “fruit fly”, acts as a living insect bioreactor, capable of expressing recombinant proteins on demand. The line subject to this notification expresses a growth factor protein that is intended for use as a component of cell culture medium for research use.

The EntoEngine fly line has been genetically engineered to express a growth factor isolated from cows. Growth factors are the unique cell signaling molecules that play important roles in cell proliferation and development. The gene sequence poses no known risks to either humans or animals. Expression of the gene encoding the growth factor is under the control of a gene expression regulator isolated from yeast. A chromosome stabilizer increases the stability of the line.

Join in: How to participate

All interested parties are invited to share scientific information and test data related to potential risks to the environment or human health from the EntoEngine fly.

By mail

Send your comments to the address in the Contact us section below.

By email

Submit your comments by email: substances@ec.gc.ca

Review our privacy statement for this consultation.

Who is the focus of this consultation

We would like to hear from:

Key questions for discussion

Canadians are invited to provide scientific information and test data that could inform the risk assessment process.

Related information

Contact us

By mail

Substances Management Information Line

Science and Technology Branch
Environment and Climate Change Canada
Place Vincent Massey, 351 St. Joseph Blvd
Gatineau QC K1A 0H3

Telephone: 1-800-567-1999 (Toll Free in Canada) or 1-819-938-3232 (Outside of Canada)

By email

E-mail:  substances@ec.gc.ca

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