Oxirane, (butoxymethyl)-(n-butyl glycidyl ether) (n-BGE)

CAS Registry Number 2426-08-6

What is it

Oxirane, (butoxymethyl), also known as n-butyl glycidyl ether or n-BGE, is an industrial chemical.

n-BGE is used as a diluent for epoxy resins, as a chemical used in the manufacture of other chemicals and as a stabilizer of chlorinated solvents.
In Canada, it is mainly used in epoxy resin formulations which have applications in coatings, adhesives, binders, sealants, fillers and resins.
n-BGE is not manufactured in Canada, but is imported into Canada.

Prior to the assessment, n-BGE was identified as a potential concern for human health based on its classification by international organizations as a substance which may cause cancer and genetic damage in laboratory animals, and based on a moderate potential for exposure to the general population of Canada.

Exposure to the general population of Canada to n-BGE is expected to be low and to occur predominantly via inhalation of contaminated air.

The Government of Canada has conducted a science-based evaluation of n-BGE, called a screening assessment.
The Government of Canada has concluded that n-BGE may be harmful to human health.
The Government of Canada has also concluded that n-BGE is not entering the environment in a quantity or under conditions that constitute a danger to the environment.
Screening assessments address potential for harm to the general population.

Exposure to the general population of Canada is currently considered to be low and the Government of Canada is taking action so that exposure remains low.
The Government of Canada will investigate the utility of implementing a future use notification tool. This would require that any proposed new manufacture, import or use of this substance be subject to further assessment before considering whether to allow such activities.
The proposed risk management approach document was published on March 6, 2010. The publication of the proposed risk management approach document was followed by a 60-day comment period, ending May 5, 2010.
Information on the risk management actions for n-BGE is available.

The health risks associated with a chemical depend on the hazard (its potential to cause health effects) and the dose (the amount of chemical to which you are exposed).
Although exposure to n-BGE among the general population is low, as a general precaution, Canadians are reminded when using any product, to carefully follow any safety warnings and directions.
Canadians who handle n-BGE in the workplace should consult with their occupational health and safety representative about safe handling practices, applicable laws and requirements under the Workplace Hazardous Materials Information System.