Fourteen Terpene and Terpenoid Substances Group

These substances were identified for action under the Chemicals Management Plan (CMP). The assessment focuses on 14 substances, referred to collectively under the CMP as the Fourteen Terpene and Terpenoid Substances Group, which are a part of the larger Terpenes and Terpenoids Group.

• Summary of publications
• Timelines
• Background

Summary of publications

Substance group	Subgroup	CAS RN	Common name	DSL name	Draft assessment	Risk management scope	Proposed conclusion on section 64 criteria	Follow-up activities
Fourteen Terpene and Terpenoid Substances Group	Individual	8013-10-3Table 1 Footnote a	Cade oil	Oils, cade	HTML	HTML	Meets one or more of the criteria	Refer to the risk management scope
	Individual	8023-75-4Table 1 Footnote a	Jonquil oil	Oils, jonquil		HTML	Meets one or more of the criteria	Refer to the risk management scope
	Individual	70788-30-6	Norlimbanol	Cyclohexanepropanol, 2,2,6-trimethyl-α-propyl-		None	Does not meet	None planned at this time
	Individual	84961-67-1Table 1 Footnote a	Verbena officinalis extract	Verbena officinalis, ext.		HTML	Meets one or more of the criteria	Refer to the risk management scope
	Individual	90045-36-6Table 1 Footnote a	Ginkgo biloba extract	Ginkgo biloba, ext.		HTML	Meets one or more of the criteria	Refer to the risk management scope
	Individual	3738-00-9	Amberlyn	Naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-		None	Does not meet	None planned at this time
	Individual	8016-37-3Table 1 Footnote a	Myrrh oil	Oils, myrrh		HTML	Meets one or more of the criteria	Refer to the risk management scope
	Individual	164288-52-2Table 1 Footnote a	Cork tree extract	Cork tree, Phellodendron amurense, ext.		HTML	Meets one or more of the criteria	Refer to the risk management scope
	1	8022-56-8Table 1 Footnote a	Sage oil	Oils, sage		HTML	Meets one or more of the criteria	Refer to the risk management scope
	1	8008-93-3Table 1 Footnote a	Wormwood oil	Oils, wormwood		HTML	Meets one or more of the criteria	Refer to the risk management scope
	2	3407-42-9	Isobornyl cyclohexanol  (IBCH)	Cyclohexanol, 3-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)-		HTML	Meets one or more of the criteria	Refer to the risk management scope
	2	66068-84-6	Sandal cyclohexanol	Cyclohexanol, 4-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)-		HTML	Meets one or more of the criteria	Refer to the risk management scope
	2	68877-29-2	Bornyl cyclohexanol (BCH)	Cyclohexanol, (1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)-		HTML	Meets one or more of the criteria	Refer to the risk management scope
	2	70955-71-4Table 1 Footnote a	Sandela	Phenol, 2-methoxy-, reaction products with 2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane, hydrogenated		HTML	Meets one or more of the criteria	Refer to the risk management scope
Table 1 Footnote a This CAS RN is a UVCB (substance of unknown or variable composition, complex reaction products, or biological materials). Table 1 Return to footnote a referrer

Timelines

Date	Activity
January 2026	Anticipated publication of the final assessment and proposed risk management approach.
January 25, 2025	Publication and start of 60-day public comment period on the Draft Assessment for the Fourteen Terpene and Terpenoid Substances Group and the Risk Management Scope for Certain Substances in the Fourteen Terpene and Terpenoid Substances Group. The related notice was published in the Canada Gazette, Part I: Vol. 159, No. 4.

Background

The assessment focuses on 14 substances referred to as the Fourteen Terpene and Terpenoid Substances Group. The human health risk assessment addressed 6 of the 14 substances under 2 subgroups, due to similarities in chemical structure, properties, or toxicity, while the remaining 8 substances were addressed individually. The ecological risks of substances in this group were characterized using the Ecological Risk Classification of Organic Substances (ERC) Approach. These 14 substances are a part of a larger group of 76 substances referred to collectively under the CMP as the Terpenes and Terpenoids Group.

Three of these 76 substances were subsequently determined to be of low concern to both human health and the environment through other approaches. The conclusion for CAS RN 25428-43-7 is provided in the Final Screening Assessment for the Rapid Screening of Substances with Limited General Population Exposure. Conclusions for CAS RNs 29350-73-0 and 68916-97-2 are provided in the Final Screening Assessment of Substances Identified as Being of Low Concern using the Ecological Risk Classification of Organic Substances and the Threshold of Toxicological Concern (TTC)-based Approach for Certain Substances.

Fifteen of these 76 substances (CAS RNs 80-56-8, 1113-21-9, 8000-46-2, 8002-09-3, 8006-64-2, 8007-01-0, 8007-02-1, 8008-31-9, 8008-52-4, 8008-57-9, 8014-19-5, 8015-77-8, 8016-85-1, 8021-28-1 and 9005-90-7) were assessed as a part of the Acyclic, Monocyclic, and Bicyclic Monoterpenes Group.

Sixteen of these 76 substances (CAS RNs 495-62-5, 8001-61-4, 8007-0-7, 17627-44-0, 65113-99-7, 107898-54-4, 87-44-5, 88-84-6, 3691-12-1, 4630-07-3, 68917-29-3, 489-86-1, 639-99-6, 22451-73-6, 489-84-9 and 8006-87-9) were assessed as a part of the Monocyclic and Bicyclic Sesquiterpenes Group.

Twelve of these 76 substances (CAS RNs 8006-78-8, 8016-88-4, 8022-96-6, 8024-43-9, 8024-08-6, 80-54-6, 91-51-0, 37677-14-8, 52474-60-9, 52475-86-2, 65405-84-7 and 66327-54-6) were assessed as a part of the Phenylpropanoids and Aldehydes Group.

Fourteen of these 76 substances (CAS RNs 469-61-4, 470-40-6, 489-40-7, 514-51-2, 546-28-1, 8000-27-9, 68608-32-2, 68990-83-0, 59056-62-1, 471-53-4, 4572-09-2, 8031-03-6, 84082-54-2 and 90045-38-8) were assessed as a part of the Tricyclic Sesquiterpenes and Triterpenoids Group.

Two of these 76 substances (CAS RNs 117-98-6 and 68917-65-7) were originally included in the Tricyclic Sesquiterpenes and Triterpenoids Group but have been removed to be assessed in a separate assessment.