Ethanol, 2-[(2-aminoethyl)amino]- (AEEA)

Ethanol, 2-[(2-aminoethyl)amino]-

CAS Registry Number 111-41-1

What is it?

  • Ethanol, 2-[(2-aminoethyl)amino]-, also known as AEEA, is an industrial chemical. It does not occur naturally in the environment.

How is it used?

  • AEEA is used mainly as a compound from which other compounds are made (chemical intermediate), but can also be used as a curing agent for epoxy resins; in commercial building materials; as a component of adhesives and sealants used in asphalt paving or patching; as a component in super glues and corrosion inhibitors; and as a lubricant additive.
  • AEEA can be used in the manufacture of surfactants with wide-ranging applications such as lubricating fluids, industrial detergents and fabric softeners.
  • AEEA is used in the manufacture of food packaging materials with no direct contact with food.
  • AEEA is also used as an additive for cooling systems.
  • Based on the most recent data, AEEA is imported both as a pure substance and as a component of finished products. It is not manufactured in Canada.

Why did the Government of Canada assess it?

  • AEEA was identified as a potential concern to human health based on international classification as a substance causing reproductive and developmental effects in animal studies.
  • AEEA is one of six substances in the Internationally Classified Substance Grouping, which were identified as priorities for assessment as they either met the categorization criteria of the Domestic Substances List and/or were associated with human health concerns.
  • The internationally classified substances are being considered as part of the Substance Groupings Initiative for screening assessments of their potential risks to the environment and to human health.

How are Canadians exposed to it?

  • Although the substance is used in a number of manufacturing processes, the potential for exposure of the Canadian population to AEEA from environmental media is expected to be minimal.
  • Also, Canadians are not expected to be exposed to AEEA through food consumption or the use of products available to consumers.

How is it released into the environment?

  • AEEA may be released to the environment during industrial, consumer and/or commercial uses of the pure substance or in products containing the substance.
  • The main source of release of AEEA is expected to occur from industrial uses of the pure substance when used to make other substances. 

What are the results of the assessment?

  • The Government of Canada has conducted a science-based evaluation of AEEA, called a screening assessment.
  • Screening assessments address the potential for harm to the general population of Canada and the environment.
  • Results of the final screening assessment indicate that AEEA is not expected to accumulate in organisms or remain in the environment for a long time.
  • Furthermore, the quantity of AEEA that may be released to the environment is below the level expected to cause harm to organisms.
  • The Government of Canada has therefore concluded that AEEA is not entering the environment at levels that constitute a danger to the environment.
  • The Government of Canada has also concluded that AEEA is not harmful to human health at current levels of exposure.
  • Hazards related to chemicals used in the workplace should be classified accordingly under the Workplace Hazardous Materials Information System (WHMIS).

What is the Government of Canada doing?

  • The Government of Canada published the Final Screening Assessment on AEEA on May 28, 2016.
  • There may be a concern if exposure of the general population to AEEA were to increase through, for example, an increased presence in products available to consumers. Options for monitoring changes in uses of AEEA have been considered and application of the Significant New Activity (SNAc) provisions of the Canadian Environmental Protection Act, 1999 is proposed.
  • SNAc provisions require that any proposed new manufacture, use or import of the substance be subject to further assessment to determine if the new activity requires further risk management consideration.

What can Canadians do?

  • The health risks associated with a chemical depend on the hazard (its potential to cause health effects) and the dose (the amount of chemical to which you are exposed). AEEA is not presently a concern for human health or the environment at current levels of exposure.
  • Canadians who may be exposed to AEEA in the workplace should consult with their employer and occupational health and safety representative about safe handling practices, applicable laws and requirements under the Workplace Hazardous Materials Information System (WHMIS).
  • As a general precaution, Canadians are reminded when using any product to carefully follow any safety warnings and directions, and to dispose of the products appropriately.
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