Under CEPA 1999, the risk posed by a substance is determined by considering both its hazardous properties (its potential to cause adverse human health or ecological effects) and the amount of exposure there is to people and the environment.
As a result of the draft screening assessment, the Government is proposing that the 4 substances in the Protein Derivatives and Yeast Extract Group are not harmful to human health or to the environment at levels of exposure considered in the assessment.
About these substances
The screening assessment summarized here focuses on 4 substances: yeast extract, protein hydrolyzates, collagen hydrolyzates, and isostearoyl hydrolyzed collagen (which is also referred to as "protein hydrolyzates, leather, reaction products with isostearoyl chloride''). They were assessed under the Chemicals Management Plan (CMP).
All 4 substances are derived from naturally occurring materials.
According to information gathered by the Government, substances in this Group may be used in Canada in building or construction materials, in food, for nutritional purposes in products such as protein supplements and infant formula, and in a number of products available to consumers, including natural health products and cosmetics. In addition, yeast extract and collagen hydrolyzates are formulants in pest control products.
Human and ecological exposures
Canadians may be exposed to these substances from food and from products available to consumers, including cosmetics.
According to the information considered under the ERC Approach, the 4 substances were identified as having low ecological exposure potential.
Key health and ecological effects (hazard)
The 4 substances in the Protein Derivatives and Yeast Extract Group were considered to be of low hazard potential for the human health assessment.
According to information considered under the ERC Approach, yeast extract, protein hydrolyzates, and collagen hydrolyzates were identified as having a low ecological hazard potential. Isostearoyl hydrolyzed collagen was identified as having a high ecological hazard potential based on its high level of ecotoxicity and bioaccumulation potential.
Risk assessment outcomes
On the basis of the information presented in the draft screening assessment, the risk to human health from substances in the Protein Derivatives and Yeast Extract Group is considered to be low.
Based upon the outcome of the ERC Approach, these 4 substances are considered unlikely to be causing ecological harm.
The Government is proposing that yeast extract, protein hydrolyzates, collagen hydrolyzates, and isostearoyl hydrolyzed collagen are not harmful to human health, and that these 4 substances are not entering the environment at levels that are harmful.