Drug and Health Product Submissions Under Review (SUR): New drug submissions under review

This list is current as of: 2025-11-30.

An Excel version of the updated SUR List is available from the Overview page.

Submissions currently under review: New drug submissions
Medicinal Ingredient(s) Therapeutic Area Year, Month Submission was Accepted into Review Company Name (available for submissions accepted into review on or after October 1, 2018) Submission 'Class' (if applicable) (available for submissions accepted into review on or after October 1, 2018)

(18F)PSMA-1007

Diagnostic radiopharmaceuticals

2025-09

Centre for Probe Development and Commercialization

New active substance

Being reviewed under the Submissions Relying on Third-Party Data Guidance

Afamelanotide

Emollients and protectives

2024-12

Clinuvel, Inc.

New active substance

Aflibercept

Ophthalmologicals

2025-07

JAMP Pharma Corporation

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Aprocitentan

Antihypertensives

2025-01

Idorsia Pharmaceuticals Ltd

New active substance

Aripiprazole

Psycholeptics

2024-09

Odan Laboratories Ltd

Being reviewed under the Submissions Relying on Third-Party Data Guidance

Atrasentan hydrochloride

Agents acting on the renin-angiotensin system

2025-07

Novartis Pharmaceuticals Canada Inc

New active substance

Avacincaptad pegol

Ophthalmologicals

2025-02

Astellas Pharma Canada Inc

New active substance

Part of 'aligned review' with a health technology assessment organization

Avibactam sodium, ceftazidime

Antibacterials for systemic use

2025-08

Sterimax Inc

New active substance

Being reviewed under the Priority Review Policy

Being reviewed under the Submissions Relying on Third-Party Data Guidance

Axatilimab

Immunosuppressants

2025-01

Incyte Corporation

New active substance

Bempedoic acid, ezetimibe

Lipid modifying agents

2025-01

HLS Therapeutics Inc

Not applicable

Betamethasone dipropionate, calcipotriol monohydrate

Antipsoriatics

2025-07

Glenmark Pharmaceuticals Canada Inc.

Not applicable

Benzoyl peroxide, tretinoin

Anti-acne preparations

2025-02

Searchlight Pharma Inc

Not applicable

Bevacizumab

Antineoplastic agents

2025-06

Curateq Biologics Private Limited

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Bimatoprost

Ophthalmologicals

2025-10

Laboratoires Thea

Not applicable

Camizestrant

Endocrine therapy

2025-10

AstraZeneca Canada Inc

New active substance

Part of 'aligned review' with a health technology assessment organization

Carbidopa, levodopa

Anti-parkinson drugs

2025-07

Knight Therapeutics Inc.

Not applicable

Ceftaroline fosamil

Antibacterials for systemic use

2025-07

Sterimax Inc.

New active substance

Being reviewed under the Submissions Relying on Third-Party Data Guidance

Chikungunya virus virus-like particle (CHIKV VLP)

Vaccines

2025-07

Bavarian Nordic AS

New active substance

Chloroprocaine hydrochloride

Ophthalmologicals

2025-02

Apotex Inc

Part of 'aligned review' with a health technology assessment organization

Cilastatin sodium, imipenem, relebactam

Antibacterials for systemic use

2025-05

Merck Canada Inc

New active substance

Being reviewed under the Priority Review Policy

Citalopram hydrobromide

Psychoanaleptics

2025-08

Mint Pharmaceuticals Inc

Not applicable

Clesrovimab

Immune sera and immunoglobulins

2025-04

Merck Canada Inc

New active substance

Clobetasol propionate

Ophthalmologicals

2025-03

Apotex Inc

Part of 'aligned review' with a health technology assessment organization

Cyclosporine

Ophthalmologicals

2025-01

Apotex Inc

Not applicable

Cysteamine hydrochloride

Ophthalmologicals

2024-05

Leadiant Biosciences, Inc.

Part of 'aligned review' with a health technology assessment organization

Denosumab

Drugs for treatment of bone diseases

2024-05

Samsung Bioepis Co., Ltd

Biosimilar

Denosumab

Drugs for treatment of bone diseases

2024-05

Samsung Bioepis Co., Ltd

Biosimilar

Denosumab

Drugs for treatment of bone diseases

2024-07

Mantra Pharma Inc.

Biosimilar

Denosumab

Drugs for treatment of bone diseases

2024-09

Shanghai Henlius Biotech, Inc.

Biosimilar

Denosumab

Drugs for treatment of bone diseases

2024-09

Shanghai Henlius Biotech, Inc.

Biosimilar

Denosumab

Drugs for treatment of bone diseases

2024-10

Biosimilar Collaborations Ireland Limited

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Denosumab

Drugs for treatment of bone diseases

2024-10

Biosimilar Collaborations Ireland Limited

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Denosumab

Drugs for treatment of bone diseases

2024-11

Apotex Inc

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Denosumab

Drugs for treatment of bone diseases

2024-11

Apotex Inc

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Denosumab

Drugs for treatment of bone diseases

2025-06

Fresenius Kabi Canada Ltd

Biosimilar

Denosumab

Drugs for treatment of bone diseases

2025-06

Fresenius Kabi Canada Ltd

Biosimilar

Denosumab

Drugs for treatment of bone diseases

2025-09

JAMP Pharma Corporation

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Denosumab

Drugs for treatment of bone diseases

2025-09

JAMP Pharma Corporation

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Depemokimab

Drugs for obstructive airway diseases

2025-04

GlaxoSmithKline Inc

New active substance

Part of 'aligned review' with a health technology assessment organization

Donanemab

Psychoanaleptics

2024-02

Eli Lilly Canada Inc

New active substance

Part of 'aligned review' with a health technology assessment organization

Doravirine, islatravir

Antivirals for systemic use

2025-08

Merck Canada Inc

New active substance

Eculizumab

Immunosuppressants

2022-07

Amgen Canada Inc

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Eculizumab

Immunosuppressants

2023-05

Amgen Canada Inc

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Eculizumab

Immunosuppressants

2023-07

Samsung Bioepis Co., Ltd

Biosimilar

Epinephrine

Drugs for obstructive airway diseases

2025-02

ARS Pharmaceuticals Operations, Inc.

Part of 'aligned review' with a health technology assessment organization

Escitalopram oxalate

Psychoanaleptics

2025-09

Orimed Pharma Inc

Not applicable

Fenfluramine hydrochloride

Antiepileptics

2025-11

UCB Canada Inc

Part of 'aligned review' with a health technology assessment organization

Gabapentin

Analgesics

2025-11

Rubicon Research Canada Limited

Not applicable

Gadopiclenol

Contrast media

2025-04

Bracco Imaging Canada

New active substance

Gadoquatrane

Contrast media

2025-09

Bayer Inc

New active substance

Gepirone hydrochloride

Psychoanaleptics

2025-08

Xediton Pharmaceuticals Inc

New active substance

Glucagon

Pancreatic hormones

2024-11

Lupin Pharma Canada Limited

Not applicable

Golimumab

Immunosuppressants

2025-06

JAMP Pharma Corporation

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Imlunestrant tosylate

Antineoplastic agents

2025-02

Eli Lilly Canada Inc

New active substance

Part of an 'aligned review' with a health technology assessment organization

Latanoprost

Ophthalmologicals

2025-01

Orimed Pharma Inc

Not applicable

Latanoprost, timolol maleate

Ophthalmologicals

2025-01

Orimed Pharma Inc

Not applicable

Lenacapavir sodium

Antivirals for systemic use

2025-06

Gilead Sciences Canada Inc

Part of an 'aligned review' with a health technology assessment organization

Leniolisib

Immunostimulants

2023-10

Pharming Technologies BV

New active substance

Being reviewed under the Priority Review Policy

Part of 'aligned review' with a health technology assessment organization

Leuprolide mesylate

Endocrine therapy

2025-06

Accord Healthcare Inc

Part of an 'aligned review' with a health technology assessment organization

Levothyroxine sodium

Thyroid therapy

2025-07

Biosyent Pharma Inc

Being reviewed under the Submissions Relying on Third-Party Data Guidance

Linerixibat

Bile and liver therapy

2025-08

GlaxoSmithKline Inc

New active substance

Metformin hydrochloride

Drugs used in diabetes

2025-05

Pharmaris Canada Inc

Not applicable

Metformin hydrochloride

Drugs used in diabetes

2025-11

Orimed Pharma Inc

Not applicable

Methohexital sodium

Anesthetics

2024-09

Sterimax Inc

Being reviewed under the Submissions Relying on Third-Party Data Guidance

Mosunetuzumab

Antineoplastic agents

2025-06

Hoffmann-La Roche Limited

New active substance

Being reviewed under the Notice of Compliance with Conditions Guidance

Part of 'aligned review' with a health technology assessment organization

Mosunetuzumab

Antineoplastic agents

2025-08

Hoffmann-La Roche Limited

Being reviewed under the Notice of Compliance with Conditions Guidance

Nadofaragene firadenovec

Antineoplastic agents

2025-04

Ferring Inc

New active substance

Part of 'aligned review' with a health technology assessment organization

Nemolizumab

Other dermatological preparations

2024-06

Galderma Canada Inc.

New active substance

Part of 'aligned review' with a health technology assessment organization

Nipocalimab

Immunosuppressants

2025-01

Janssen inc

New active substance

Octreotide hydrochloride

Pituitary and hypothalamic hormones and analogues

2025-11

Camurus AB

Not applicable

Olezarsen sodium

Lipid modifying agents

2025-06

Theratechnologies Inc

New active substance

Being reviewed under the Priority Review Policy

Part of 'aligned review' with a health technology assessment organization

Palopegteriparatide

Calcium homeostasis

2025-03

Pendopharm Division of Pharmascience Inc

New active substance

Part of 'aligned review' with a health technology assessment organization

Pegfilgrastim

Immunostimulants

2025-03

Curateq Biologics Private Limited

Biosimilar

Pegunigalsidase alfa

Other alimentary tract and metabolism products

2024-11

Chiesi Farmaceutici S.P.A.

New active substance

Pegzilarginase

Other alimentary tract and metabolism products

2025-10

Immedica Pharma AB

New active substance

Being reviewed under the Priority Review Policy

Part of 'aligned review' with a health technology assessment organization

Pertuzumab

Antineoplastic agents

2025-05

Shanghai Henlius Biotech, Inc.

Biosimilar

Plozasiran

Lipid modifying agents

2025-07

Arrowhead Pharmaceuticals, Inc.

New active substance

Being reviewed under the Priority Review Policy

Pregabalin

Analgesics

2025-01

Orimed Pharma Inc

Being reviewed under the Submissions Relying on Third-Party Data Guidance

Part of 'aligned review' with a health technology assessment organization

Ranibizumab

Ophthalmologicals

2025-08

Apotex Inc

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Remibrutinib

Immunosuppressants

2025-09

Novartis Pharmaceuticals Canada Inc

New active substance

Part of 'aligned review' with a health technology assessment organization

Rifapentine

Antimycobacterials

2025-03

Macleods Pharmaceuticals Limited

New active substance

Part of 'aligned review' with a health technology assessment organization

Rituximab

Antineoplastic agents

2024-02

Dr. Reddy's Laboratories SA

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Ropeginterferon alfa-2b

Immunostimulants

2025-09

Forus Therapeutics Inc

New active substance

Sevabertinib

Antineoplastic agents

2025-05

Bayer Inc

New active substance

Being reviewed under the Notice of Compliance with Conditions Guidance

Part of 'aligned review' with a health technology assessment organization

Sotagliflozin

Drugs used in diabetes

2025-10

BGP Pharma ULC

New active substance

Part of 'aligned review' with a health technology assessment organization

Testosterone undecanoate

Sex hormones and modulators of the genital system

2025-01

Tolmar International Ltd.

Not applicable

Testosterone undecanoate

Sex hormones and modulators of the genital system

2025-09

Verity Pharmaceuticals Inc

Not applicable

Tislelizumab

Antineoplastic agents

2025-02

BeOne Medicines I GmbH

New active substance

Part of 'aligned review' with a health technology assessment organization

Tislelizumab

Antineoplastic agents

2025-06

Beigene Switzerland GmbH

Not applicable

Tolebrutinib

Immunosuppressants

2025-08

Sanofi-Aventis Canada Inc

New active substance

Tovorafenib

Antineoplastic agents

2025-10

Ipsen Biopharmaceuticals Canada Inc

New active substance

Being reviewed under the Notice of Compliance with Conditions Guidance

Part of 'aligned review' with a health technology assessment organization

Trastuzumab

Antineoplastic agents

2017-11

Not available

Not available

Trastuzumab

Antineoplastic agents

2017-11

Not available

Not available

Trastuzumab

Antineoplastic agents

2018-02

Not available

Not available

Trastuzumab

Antineoplastic agents

2025-09

Curateq Biologics Private Limited

Biosimilar

Part of 'aligned review' with a health technology assessment organization

TrenibotulinumtoxinE

Muscle relaxants

2025-09

Abbvie Corporation

New active substance

Ustekinumab

Immunosuppressants

2024-05

Accord Healthcare Inc

Biosimilar

Part of 'aligned review' with a health technology assessment organization

Varenicline

Ophthalmologicals

2025-11

BGP Pharma ULC

Not applicable

Viloxazine hydrochloride

Psychoanaleptics

2024-12

Knight Therapeutics Inc.

New active substance

Vosoritide

Drugs for treatment of bone diseases

2025-02

Biomarin International Limited

New active substance

Zanidatamab

Antineoplastic agents

2025-04

Jazz Pharmaceuticals Ireland Limited

New active substance

Being reviewed under the Notice of Compliance with Conditions Guidance

Zuranolone

Psychoanaleptics

2024-12

Biogen Canada Inc

New active substance

Page details

2025-12-23