Canada’s roles and progress in poliovirus containment

On this page

• Global polio eradication campaign
• What we're doing
• National Authority for Containment of Poliovirus
• Poliovirus essential facilities
• Poliovirus potentially infectious materials and novel poliovirus strains
• Contact

Global polio eradication campaign

The Global Polio Eradication Initiative works towards eliminating polioviruses that remain in circulation in the population: wild poliovirus type 1 and vaccine-derived poliovirus.

As part of this initiative, World Health Organization (WHO) member states are preparing to contain all types of polioviruses only in certified safe and secure facilities. This will reduce the risk of laboratory containment breaches reintroducing polio to the population.

The Government of Canada has committed to this initiative under World Health Assembly resolution 71.16, and is working towards keeping Canadians healthy and safe through containing polioviruses.

Learn more about:

• The Global Polio Eradication Initiative
• World Health Assembly resolution 71.16 (PDF)
• Global Poliovirus Containment Action Plan 2022 to 2024 (PDF)

What we're doing

The Public Health Agency of Canada Centre for Biosecurity has established a National Authority for Containment of Poliovirus. It has significantly reduced the number of facilities storing polioviruses in Canada.

We've also successfully completed a national poliovirus inventory survey, and promoted destruction or transfer of all unnecessary poliovirus materials in Canada.

In support of laboratory audits under the WHO's Global Action Plan for poliovirus containment, Canada was:

• the first country to be awarded an Interim Certificate of Containment for a Poliovirus Essential Facility
• among the first member states in the world to have approved qualified auditors for inspecting poliovirus essential facilities

The strict audit process ensures Canadian facilities certified to work with polioviruses do so in a safe and secure manner. These measures are in-place to protect the general Canadian public, and support the global polio eradication campaign.

Canada's legislative authority under the Human Pathogens and Toxins Act requires any facility working with poliovirus to:

• have a Risk Group 3 (RG3) licence
• meet the Canadian Biosafety Standard requirements for Containment Level 3

Canadian facilities must:

• attest to whether they possess poliovirus during the licence application process
• receive approval from the Centre for Biosecurity to perform controlled activities with polioviruses

Learn more about:

• Guidance for the response and management of a poliovirus event or outbreak in Canada
• Human Pathogens and Toxins Act
• WHO Global Action Plan for Poliovirus Containment, 4^th edition (PDF)

National Authority for Containment of Poliovirus

The National Authority for the Containment of Poliovirus's responsibilities under the WHO's Global Action Plan include:

• determining the critical national functions that justify keeping poliovirus in facilities
• designating the facilities serving these critical functions that involve the handling and storage of needed poliovirus materials
• confirming that applications for containment certification meet requirements under Canadian legislation and the Global Action Plan
• verifying that established mechanisms, including regular inspection and audit programmes, align with the WHO's containment certification scheme.
• reviewing and processing applications for containment certification, so that designated facilities serving critical functions enter the containment certification process.

In addition, they:

• coordinate training for auditors and poliovirus essential facilities
• submit an annual report to the WHO on poliovirus containment progress
• coordinate with Canadian stakeholders on poliovirus containment and perform outreach

Poliovirus essential facilities

Facilities that handle and store eradicated types of poliovirus will require certification as a poliovirus essential facility. This type of facility maintains the ability to work with and store infectious and potentially infectious poliovirus materials. They serve critical national and international functions, including:

• diagnostics
• vaccine testing
• vaccine production
• public health and virologic research

Poliovirus essential facilities must be certified to meet global containment requirements through the WHO's comprehensive Containment Certification Scheme. Qualified auditors from the Centre for Biosecurity inspect these facilities to ensure they meet stringent requirements for:

• biosafety
• biosecurity
• engineering
• health programs
• emergency preparedness
• laboratory equipment and maintenance

Poliovirus potentially infectious materials and novel poliovirus strains

Facilities that handle or store poliovirus potentially infectious material or novel poliovirus strains must inform the Centre for Biosecurity.

Potentially infectious materials include any:

• respiratory samples
• human faecal samples
• concentrated sewage samples that were:
  • collected when:
    • poliovirus was in circulation or
    • oral poliovirus vaccine was in use
  • stored in conditions that support poliovirus survival

Learn more about:

• Biosafety and Biosecurity for Pathogens and Toxins Newsletter:
  • Poliovirus potentially hazardous material
  • New tool to identify poliovirus potentially infectious material samples
• How facilities can determine whether they possess potentially infectious materials (PDF)
• Polio (poliomyelitis): Wastewater surveillance

Contact

National Authority for the Containment of Polioviruses

Email: polio@phac-aspc.gc.ca

Centre for Biosecurity

Email: biosafety.biosecurite@phac-aspc.gc.ca