ARCHIVED - Human Immunodeficiency Virus (HIV)

Nationally notifiable since 1995

1.0 National Notification

Only confirmed cases of disease should be notified.

2.0 Type of Surveillance

Routine case-by-case notification to the federal level

3.0 Case Classification

3.1 Confirmed case

Adults, Adolescents and Children ≥ 18 months:

• detection of HIV antibody with confirmation (e.g. EIA screening with confirmation by Western blot or other confirmatory test)
  OR
• detection of HIV nucleic acid (e.g. DNA PCR or plasma RNA)
  OR
• HIV p24 antigen with confirmation by neutralization assay
  OR
• isolation of HIV in culture

Children < 18 months (on two separate samples collected at different times):

• detection of HIV nucleic acid (e.g. DNA PCR or plasma RNA)
  OR
• HIV p24 antigen with confirmation by neutralization assay
  OR
• isolation of HIV in culture

4.0 Laboratory Comments

In children < 18 months of age born to HIV-positive women, nucleic acid testing should be done within two weeks after birth and, if negative, repeated at 1 to 2 months and at 3 to 4 months of age. Any positive results should be repeated with a second specimen for confirmation.

For children who are born to HIV-positive women and who have negative nucleic acid results, antibody testing should be done at 12 and 18 months of age to ensure that they have lost maternally derived antibodies. (This is not used to determine uninfected status but rather to eliminate the possibility of a positive antibody result being misinterpreted.) These children should continue to be monitored until they have a negative HIV antibody test.

5.0 Clinical Evidence

6.0 ICD Code(s)

6.1 ICD-10 Code(s)

B20-B24

6.2 ICD-9 Code(s)

042-044

7.0 Type of International Reporting

Informal sharing of data on a regular basis with the WHO, Pan American Health Organization and Joint United Nations Programme on HIV/AIDS

8.0 Comments

9.0 References

Case definitions for diseases under national surveillance. CCDR 2000;26(S3). Retrieved May 2008, from http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/00vol26/26s3/index.html

Date of Last Revision/Review:

May 2008