Sulfurized isobutylene - information sheet
CAS Registry Number 68511-50-2
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- About this substance
- Human and ecological exposures
- Key health and ecological effects (hazard)
- Risk assessment outcomes
- Related information
- The Government of Canada conducted a science-based evaluation, called a screening assessment, to address the potential for harm to Canadians and to the environment from sulfurized isobutylene.
- Under the Canadian Environmental Protection Act, 1999 (CEPA 1999), the risk posed by a substance is determined by considering both its hazardous properties (its potential to cause adverse human health or ecological effects) and the amount of exposure there is to people and the environment. A substance may have hazardous properties; however, the risk to human health or to the environment may be low depending upon the level of exposure.
- The ecological hazard and exposure potential of this substance was classified using the Ecological Risk Classification of Organic Substances (ERC) Approach.
- As a result of the draft screening assessment, the Government is proposing that sulfurized isobutylene is not harmful to human health or the environment at levels of exposure considered in the assessment.
About this substance
- The screening assessment focuses on 1-propene, 2-methyl, sulfurized, also referred to as sulfurized isobutylene. It was assessed as part of the Chemicals Management Plan.
- Sulfurized isobutylene is a substance of Unknown or Variable Composition, Complex Reaction Products, or Biological Materials (UVCBs). It does not naturally occur in the environment. According to information gathered by the Government, this substance is mainly used in automotive lubricants and greases in Canada.
Human and ecological exposures
- Canadians may be exposed to sulfurized isobutylene from environmental sources, specifically, drinking water, and during the use of products available to consumers such as lubricants and greases.
- According to the information considered under the ERC Approach, sulfurized isobutylene was identified as having low ecological exposure potential.
Key health and ecological effects (hazard)
- To identify health effects information, international reports of data were considered. This included a review by the United States Environmental Protection Agency on alkyl sulfides.
- The critical effects identified for characterizing the risk to human health in the screening assessment were decreased bodyweight and blood system effects, following dermal exposure to sulfurized isobutylene.
- There were limited health effects data for this substance; therefore, a comparative approach, called read-across, using data available for similar substances was used to assess potential health effects. Developmental effects were identified as a critical effect following long-term oral exposure to sulfurized isobutylene.
- According to information considered under the ERC Approach, sulfurized isobutylene was identified as having a low ecological hazard potential.
Risk assessment outcomes
- Using a comparison of levels to which Canadians may be exposed to sulfurized isobutylene, and levels associated with critical effects, it was determined that the risk to human health is low.
- Based upon the outcome of ERC Approach, sulfurized isobutylene is considered unlikely to be causing ecological harm.
- The Government of Canada published the Draft Screening Assessment for Sulfurized Isobutylene on July 4, 2020. The public is invited to comment on the assessment during the 60-day public comment period ending on September 2, 2020.
Proposed screening assessment conclusions
- As a result of the draft screening assessment, the Government is proposing that sulfurized isobutylene is not harmful to human health at levels of exposure considered in the assessment, and is not entering the environment at levels that are harmful to the environment.
- Sulfurized isobutylene may be found in products available to consumers. Canadians should follow any safety warnings and directions related to the product, and dispose of products responsibly.
- The screening assessment for sulfurized isobutylene focused on potential risks of exposure to the general population of Canada, rather than occupational exposure. Hazards related to chemicals used in the workplace are defined within the Workplace Hazardous Materials Information System. For information concerning workplace health and safety and what steps to take in the workplace, Canadians should consult their employer and/or the Occupational Health and Safety Regulator in their jurisdiction.
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