The risks posed by a substance are determined by both its hazardous properties (potential to cause adverse human health or ecological effects) and the amount or extent of exposure to people and the environment.
When needed, the Government implements risk management measures under CEPA 1999 and other federal acts to help prevent or reduce potential harm.
Sulfurized isobutylene is associated with health effects; however, at levels of exposure considered in the assessment, the Government concluded that it is not harmful to human health or to the environment.
The critical effects identified for characterizing the risk to human health in the screening assessment were decreased bodyweight and blood system effects, following dermal exposure to sulfurized isobutylene.
There were limited health effects data for this substance; therefore, a comparative approach, called read-across, using data available for similar substances was used to assess potential health effects. Developmental effects were identified as a critical effect following long-term oral exposure to sulfurized isobutylene.
According to information considered under the ERC Approach, sulfurized isobutylene was identified as having a low ecological hazard potential.
Consideration of vulnerable populations
There are groups of individuals within the Canadian population who, due to greater susceptibility or greater exposure, may be more likely to experience adverse health effects from exposure to substances.
Certain subpopulations are routinely considered throughout the screening assessment process, such as infants, children, and people of reproductive age. For instance, age-specific exposure estimates are routinely derived and developmental and reproductive toxicity studies are evaluated for potential health effects. These subpopulations were taken into account in the risk assessment outcomes of sulfurized isobutylene.
Risk assessment outcomes
Using a comparison of levels at which Canadians may be exposed to sulfurized isobutylene, and levels associated with critical effects, it was determined that the risk to human health is low.
Based upon the outcome of ERC Approach, sulfurized isobutylene is considered unlikely to be causing ecological harm.
Screening assessment conclusions
The Government concluded that sulfurized isobutylene is not harmful to human health at levels of exposure considered in the assessment, and is not entering the environment at levels that are harmful.
Sulfurized isobutylene may be found in products available to consumers. Canadians should follow any safety warnings and directions related to the product, and dispose of products responsibly.
Use the Substances Search tool to find substances that are referenced in certain legislative or regulatory instruments or on Government of Canada websites.