Guidance on regulating medical devices manufactured from or incorporating viable or non-viable animal tissue or their derivative(s): Appendix


Medical devices may:

The following table presents animal and human tissues and derivatives used in medical devices that are or have been licensed in Canada.

Species/tissue Bovine Equine Ovine HumanFootnote 1 Porcine Rooster Shark Shrimp Silk (worm) Fish
Amniotic membrane       yes            
Artery/vein yes                  
Blood and products (albumin, gelatin, collagen, rhAlbumin, thrombin) yes     yes yes          
Bone and products (collagen, gelatin, tallow) yes     yes yes          
Cartilage and chondroitin sulfate yes           yes      
Comb and products (gelatin, hyaluronic acid, sodium hyaluronate)           yes        
Demineralized bone   yes   yes            
Elastin (ligament) yes                  
Fibroblast and products (collagen, albumin) yes     yes yes          
Fat/tallow yes       yes          
Fish oil                   yes
Heart valve and products (collagen, gelatin) yes yes   yes yes          
Heparin (intestine- or mucosa-derived) yes       yes          
Hide or skin and products (collagen, gelatin, thrombin) yes yes   yes yes          
Hyaluronic acid                 yes  
Hydroxyapatite (bone-derived) yes                  
Intestine and products (collagen, heparin) yes   yes   yes          
Meat         yes          
Milk casein and gelatin yes       yes          
Mucosa and products (collagen, heparin, pepsin, sodium hyaluronate) yes   yes   yes          
Pericardium and collagen yes yes     yes          
Peritoneum and collagen         yes          
Pepsin (mucosa-derived)         yes          
Placenta collagen       yes            
Rh demineralized bone       yes            
Sclera collagen         yes          
Serosa and collagen yes                  
Serum and products (albumin, rhAlbumin) yes     yes yes          
Shell chitosan               yes    
Silk fibrin                 yes  
Tendon collagen and gelatin yes       yes          
Footnote 1

While some licensed medical devices include human tissues and/or derivatives, requirements for those tissues are outside of the scope of this guidance.

Return to footnote 1 referrer

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