Notice of Modification to the List of permitted supplemental ingredients to enable the use of L-alpha-glycerylphosphorylcholine in supplemented foods
Reference Number: NOM/ADM SI-006
September 20, 2023
Health Canada's Food Directorate completed a safety assessment of L-alpha-glycerylphosphorylcholine (also called alpha GPC or choline alfoscerate) for use in supplemented foods.
Health Canada published a Notice of proposal to enable the use of L-alpha-glycerylphosphorylcholine as a supplemental ingredient in foods (NOP/ADP SI-006) on April 17, 2023. The proposal was open to the public for comment for 75 days. A summary of the comments that were provided during this period with any applicable responses is available in the information document referenced below.
The results of this safety assessment support the safety of L-alpha-glycerylphosphorylcholine as a source of supplemental choline for use in supplemented foods. Consequently, Health Canada has enabled the use of L-alpha-glycerylphosphorylcholine described in the information document below by modifying the List of permitted supplemental ingredients, effective September 20, 2023.
Health Canada's Food Directorate is committed to reviewing new scientific information regarding the safety of any permitted ingredient, including L-alpha-glycerylphosphorylcholine. Anyone wishing to submit an inquiry or new scientific information on the use of this ingredient may do so in writing, by regular mail or electronically. If you wish to contact the Food Directorate electronically, please use the words "Alpha GPC (NOM SI-006)" in the subject line of your e-mail.
Bureau of Nutritional Sciences, Food Directorate
251 Sir Frederick Banting Driveway
Tunney's Pasture, A.L.: 2203E
Ottawa, Ontario K1A 0K9
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