Information on the use of certain ingredients in foods including supplemented foods

While L-carnitine is naturally present in a variety of foods consumed as part of the diet, and acetyl-L-carnitine is synthesized in the body, neither have a history of use as ingredients added to foods.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on acetyl-L-carnitine/L-carnitine".

While alpha-lipoic acid is synthesized in the body, and it occurs naturally in foods, levels are relatively low and there is no history of use as an ingredient added to foods.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on alpha-lipoic acid".

More information is required for Health Canada to make a determination on whether a specific coffee fruit extract has a history of use as a food ingredient.

Coffee fruit extract did not undergo evaluation for use as a supplemental ingredient. A pre-market submission can be made for consideration as a supplemental ingredient.

This ingredient has a history of use in foods when prepared and used in a manner consistent with that of a flavouring. However, Health Canada has not determined a maximum level for its safe use as a food ingredient.

This ingredient did not undergo evaluation for use as a supplemental ingredient. A pre-market submission can be made for its consideration as a supplemental ingredient.

This ingredient has a history of use in foods when prepared and used in a manner consistent with that of a flavouring. However, Health Canada has not determined a maximum level for its use as a food ingredient, outside of its use as a supplemental ingredient with corresponding conditions of use.

A Notice of Proposal was published in August 2022 for use of "Grape seed extract (oligomeric proanthocyanidins)" as a supplemental ingredient in supplemented foods under the conditions of use set out in the listing.

More information is required for Health Canada to make a determination on whether a specific extract has a history of use as a food ingredient.

Green coffee bean extract did not undergo evaluation for use as a supplemental ingredient. A pre-market submission can be made for its consideration as a supplemental ingredient.

Camellia sinensis, when prepared and used in a manner consistent with that of a flavouring, has a history of use in foods. One cup of green tea may provide approximately 100 mg of epigallocatechin gallate (EGCG) and 200 mg of total catechins (primary constituents of green tea extract). However, Health Canada has not determined a maximum level for its safe use as a food ingredient, outside of its use as a supplemental ingredient with corresponding conditions of use.

A Notice of Modification was published in January 2024 for use of "Green tea extract (EGCG/catechins)" as a supplemental ingredient in supplemented foods under the conditions of use set out in the listing.^{Footnote 4}

More information is required for Health Canada to make a determination on whether a specific extract has a history of use as a food ingredient.

Guarana seed extract did not undergo evaluation for use as a supplemental ingredient. A pre-market submission can be made for its consideration as a supplemental ingredient.

While 5-HTP is synthesized in the body, its natural occurrence in foods is limited and there is no history of use as an ingredient added to foods.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on 5-hydroxytryptophan".

Maca root powder has a history of use as food; however, its extracts cannot be considered equivalent.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on maca root extract".

Whole or minimally processed mangosteen fruit has a history of use as food; however, its rind extracts cannot be considered equivalent.

This ingredient did not undergo evaluation for use as a supplemental ingredient. A pre-market submission can be made for consideration as a supplemental ingredient.

This ingredient has a history of use in foods when prepared and used in a manner consistent with that of a flavouring, at levels not exceeding 8 mg per day of ginsenosides. However, Health Canada has not determined a maximum level for its safe use as a food ingredient. A product providing more than 8 mg per day of ginsenosides may result in a potentially therapeutic level.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on panax ginseng root extract".

Extracts of aerial parts of passionflower (Passiflora incarnata), when prepared and used in a manner consistent with that of a flavouring, have a history of use in foods. However, Health Canada has not determined a maximum level for its safe use as a food ingredient.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on passionflower extract".

While phosphatidylserine is a naturally occurring phospholipid that is part of the diet, significant compositional variations exist based on its source and there is no history of use as an ingredient added to foods.

A Notice of Modification was published in April 2024 for use of "Phosphatidylserine (soy)" as a supplemental ingredient in supplemented foods under the conditions of use set out in the listing.

Pomegranate fruit arils (seeds) and pomegranate juice have a history of use as foods; however, its rind extracts cannot be considered equivalent.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on pomegranate rind extract".

While quercetin is naturally present in a variety of foods that are consumed as part of the diet, it does not have a history of use as an ingredient added to foods.

This ingredient did not undergo evaluation for use as a supplemental ingredient. A pre-market submission can be made for consideration as a supplemental ingredient.

Resveratrol has a history of use as a food ingredient at an intake of less than or equal to 4 mg per day. However, Health Canada has not determined a maximum level for its safe use as a food ingredient.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on resveratrol".

Whole or minimally processed schisandra chinensis berries have a history of use as a flavouring in foods. The extract also has a history of use as a food ingredient at levels not exceeding 200 mg per day of the equivalent crude quantity of dried berry. However, Health Canada has not determined a maximum level for its safe use as a food ingredient. Use of the extract that results in an intake of greater than 1200 mg per day of the equivalent crude quantity of dried berry may result in a potentially therapeutic level.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on schisandra chinensis fruit extract".

While siberian ginseng was previously listed as a flavour by the Council of Europe, it was removed from the flavour listing because it was determined to be added for therapeutic purposes only.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on Siberian ginseng root and/or root extract".

L-theanine has a history of use in foods when used at a level not exceeding 23 mg per day. However, Health Canada has not determined a maximum level for its safe use as a food ingredient. A product providing more than 200 mg per day of L-theanine may result in a potentially therapeutic level.

Data required for further consideration as a supplemental ingredient, as described in the "Information on the use of L-theanine".

Theobromine occurs naturally in some foods, and has a history of use in foods when prepared and used in a manner consistent with that of a flavouring. However, Health Canada has not determined a maximum level for its safe use as a food ingredient.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on theobromine".

Valerian root extract has a history of use in foods when prepared and used in a manner consistent with that of a flavouring. However, Health Canada has not determined a maximum level for its safe use as a food ingredient.

Data required for further consideration as a supplemental ingredient, as described in the "Decision on valerian root extract".

More information is required for Health Canada to make a determination on whether a specific extract has a history of use as a food ingredient.

An ingredient that has been purified or enriched in a manner that increases its caffeine content compared to the natural ingredient is considered to be "caffeine" as a supplemental ingredient.

More information is required for Health Canada to make a determination on whether a specific extract has a history of use as a food ingredient.

This ingredient did not undergo evaluation for use as a supplemental ingredient. A pre-market submission can be made for consideration as a supplemental ingredient.

As an ingredient identified for further assessment as set out in Health Canada's Category Specific Guidance for Temporary Marketing Authorization: Supplemented Food, white willow bark extract is currently under evaluation for use a supplemental ingredient. The assessment will consider data available from publicly available information. Results of the assessment will be communicated, when available.

More information is required for Health Canada to make a determination on whether a specific extract has a history of use as a food ingredient.

This ingredient did not undergo evaluation for use as a supplemental ingredient. A pre-market submission can be made for its consideration as a supplemental ingredient.