5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride (Clomipramine Hydrochloride)

CAS Registry Number 17321-77-6

What is it?

• 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride, also known as clomipramine hydrochloride, is a pharmaceutical product.

How is it used?

• Clomipramine hydrochloride can be used as an antidepressant or a painkiller. It may also be used as a medication for animals.
• Based on the most recent data available, clomipramine hydrochloride is not manufactured in Canada but is imported into Canada. It is not naturally produced in the environment.

Why did the Government of Canada assess it?

• Clomipramine hydrochloride was identified as a potential concern to the environment based on available information regarding possible persistence, accumulation in organisms and potential to cause harm to organisms.

How is it released into the environment?

• Clomipramine hydrochloride may be released to the environment during commercial handling.
• Most clomipramine hydrochloride is chemically transformed during use by consumers, and only a small proportion may be released to sewers and soil.

What is the Government of Canada doing?

• The Government of Canada has conducted a science-based evaluation of clomipramine hydrochloride called a screening assessment.
• The Government of Canada has concluded that clomipramine hydrochloride is not entering the environment in a quantity or under conditions that constitute a danger to the environment.
• Pharmaceutical uses of clomipramine hydrochloride are regulated by the Government of Canada.
• The final screening assessment was published on August 1, 2009.