Subvention d’équipe : La biologie au service de la prévention du cancer
Document d'information
Les Instituts de recherche en santé du Canada et ses partenaires, l’Institut de recherche Terry Fox, la Société canadienne du cancer, l’Agence de recherche et développement médical du Japon, la Société de recherche sur le cancer et BioCanRx, investissent de plus de 41 millions de dollars pour soutenir 19 équipes qui travailleront au cours des cinq prochaines années à l’élaboration et à la diffusion de nouvelles méthodes de prévention du cancer, de réduction des risques de cancer et de détection précoce de certains des cancers les plus fréquemment diagnostiqués au Canada et ailleurs dans le monde.
| Chercheuse principale ou chercheur principal | Aperçu des travaux de recherche | Financement |
|---|---|---|
| Sheela Abraham Université Queen’s Kingston (Ontario) |
Extracellular Vesicle-Derived Biomarkers for Early Leukaemia Detection and Monitoring Exercise-Based Risk Reduction | 1 988 650 $ |
| Mark Basik Hôpital général juif Montréal (Québec) |
Advancing Risk Stratification in Young Women at High Risk for Breast Cancer | 1 999 957 $ |
| Steven Chan Réseau universitaire de santé (Centre de cancérologie Princess-Margaret) Toronto (Ontario) |
GLP-1 Receptor Agonists as a Preventive Strategy for Clonal Hematopoiesis-Driven Hematologic Cancers | 1 999 999 $ |
| Maziar Divangahi Institut de recherche du Centre universitaire de santé McGill Montréal (Québec) |
Unlocking the Power of Trained Immunity in Cancer | 2 000 000 $ |
| Keith Fowke Université du Manitoba Winnipeg (Manitoba) |
Inflammation, Sex hormones, and Human Papilloma Virus (HPV) Expression: Assessing their Relationship in Menopausal Women and Evaluating Interventions to Prevent Cervical Cancer in Older Women | 2 000 000 $ |
| Vincent Fradet Université Laval Québec (Québec) |
Harnessing the gut microbiome-prostate cancer crosstalk to discover predictive biomarkers of risk and potential preventive strategies | 2 000 000 $ |
| Aaron Goodarzi Université de Calgary Calgary (Alberta) |
Radioactive Air Pollutant Induced Disease (RAPID) Prevention - Understanding and preventing health risks from particle radiation-emitting radioisotope inhalation, as modified by genetic ancestry and mixed exposure with combustion particulates. | 2 000 000 $ |
| Vikki Ho Centre hospitalier de l’Université de Montréal Montréal (Québec) |
Environmental eXposure Profiling for Signatures of Early ColoRectal Cancer (EXPOSE-CRC) | 2 000 000 $ |
| Rayjean Hung Institut de recherche Lunenfeld-Tanenbaum Toronto (Ontario) |
Prevention of Adiposity-related Cancers via Biology and Evidence Triangulation (PROBE) | 1 999 985 $ |
| David Huntsman BC Cancer Vancouver (Colombie-Britannique) |
Biologic basis of contraceptive choice associated ovarian cancer risk: from populations through cells to action | 2 000 000 $ |
| Alberto Martin Université de Toronto Toronto (Ontario) |
Therapeutic interventions to prevent colon cancer caused by pks+ E.coli | 2 000 000 $ |
| Christopher Maxwell Université de la Colombie-Britannique Vancouver (Colombie-Britannique) |
Targeting breast involution for the primary prevention of breast cancer among women who inherit a pathogenic variant in breast cancer 1 (BRCA1) | 1 996 790 $ |
| Luke McCaffrey Université McGill Montréal (Québec) |
Decoding Breast Cancer: How Intrinsic Factors and Distinct Tissue Microenvironments Collaboratively Drive Breast Cancer Initiation | 2 000 000 $ |
| Rachel Murphy BC Cancer Vancouver (Colombie-Britannique) |
Ultra-processed foods and cancer: advancing evidence on the biological mechanisms linking the gut microbiome, ultra-processed foods and colorectal cancer (UPFront) | 2 000 000 $ |
| Faiyaz Notta Réseau universitaire de santé (Centre de cancérologie Princess-Margaret) Toronto (Ontario) |
The ELDER Study: Timing cancer by tracking how tissue-specific aging shapes malignancy | 5 300 000 $ |
| Gina Ogilvie Université de la Colombie-Britannique Vancouver (Colombie-Britannique) |
Subsequent to LEEP Evaluation of Disease Recurrence – Systemic and Comprehensive Pan-optic Exploration (SLEEPER-SCOPE 360) – A Comprehensive Exploration of post-LEEP HPV Infection and Cervical Dysplasia Recurrence and its Associated Factors | 2 000 000 $ |
| Michael Pollak Hôpital général juif Montréal (Québec) |
Incretin-mimetic drugs for cancer prevention: Mechanisms and clinical potential | 1 975 000 $ |
| Isabella Tai BC Cancer Vancouver (Colombie-Britannique) |
Bridging gastric cancer biology to prevent progression of pre-cancerous gastric lesions | 2 000 000 $ |
| Gustavo Ybazeta Institut de recherches d’Horizon Santé‑Nord Sudbury (Ontario) |
CANCER-WISE: Cancer Associated Nucleic acids in Community Environments-Risk Detection through Wastewater-based Integrated Surveillance and Epidemiology | 2 000 000 $ |