National Advisory Committee on Immunization (NACI): Methods and process

Canadian Immunization Guide

The National Advisory Committee on Immunization (NACI) provides the Public Health Agency of Canada (PHAC) with ongoing and timely medical, scientific, and public health advice relating to immunization.

In addition to burden of disease and vaccine characteristics, as of 2019, PHAC has expanded the mandate of NACI to include the consideration of programmatic factors in developing evidence-based recommendations to facilitate timely decision-making for publicly funded vaccine programs at provincial and territorial levels.

The additional factors to be considered by NACI include: economics, ethics, equity, feasibility, and acceptability. Not all NACI Statements will require in-depth analyses of all programmatic factors.

PHAC acknowledges that the advice and recommendations set out in Advisory Committee Statements are based upon the best current available scientific knowledge at the time of publication. People administering vaccines should also be aware of the contents of the relevant product monographs, which can be found on Health Canada's Drug Product Database. NACI recommendations for use and other information set out within the Statements may differ from that set out in the product monographs of the Canadian manufacturers of the vaccines. NACI members and liaison members conduct themselves within the context of PHAC's Policy on Conflict of Interest, including yearly declaration of potential conflict of interest.

National Advisory Committee on Immunization methods and processes

• Interpretation Guide – Health Economics, 1^st edition (2024)
• Guidelines for the economic evaluation of vaccination programs in Canada, 1^st edition (2023)
• Process for incorporating economic evidence into federal vaccine recommendations (2022)
• Navigating inequities: A roadmap out of the pandemic (2021)
• A framework for the systematic consideration of ethics, equity, feasibility, and acceptability in vaccine program recommendations (2020)
• Immunization guidance products: Different levels of detail for different uses (2016)
• Canada's National Advisory Committee on Immunization (NACI): Evidence-based decision-making on vaccines and immunization (2010)
• Evidence-based recommendations for immunization – Methods of the National Advisory Committee on Immunization (2009)

History of the National Advisory Committee on Immunization

• Canada's National Advisory Committee on Immunization: Celebrating 50 years (2015)
• The National Advisory Committee on Immunization (NACI): A celebration of fifty years of service (2014)